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- W2890742708 abstract "A complex histological, histochemical and electron microscopic study of the state of the microcirculatory bed of the pancreas and conjugate transformations in the parenchyma of the organ after modeling the metabolic syndrome using a diet high in fats and carbohydrates was carried out. Spasm of arterioles, the marginal state of leukocytes and the desquamation of endotheliocytes into the lumen of a vessel, the stasis of erythrocytes in capillaries were revealed. The endothelial cells of capillaries had signs of increased transport of substances through the vessel walls: pinocytosis, fenestration, loosening of basal membranes. It was observed that capillaries are filled with shaped blood elements, on the luminal surface of endotheliocytes nuclei are protruded and the cytoplasm outgrowth into the lumen of the vessel is formed. At the same time, glucose oxidation accelerated both in the Krebs cycle and along the glycolytic pathway in the endotheliocytes of the vessels of the microcirculatory bed, indicating that the energy was supplied to the cells at a higher level. Disturbances of microcirculation were accompanied by focal destructive and inflammatory changes in the parenchyma of the organ." @default.
- W2890742708 created "2018-09-27" @default.
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- W2890742708 date "2018-09-16" @default.
- W2890742708 modified "2023-10-05" @default.
- W2890742708 title "STRUCTURAL CHANGES IN THE MICROCIRCULATORY BED OF THE PANCREAS IN RATS WITH EXPERIMENTAL METABOLIC SYNDROME" @default.
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- W2890742708 doi "https://doi.org/10.29235/1814-6023-2018-15-3-347-353" @default.
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