FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890769616> ?p ?o ?g. }

• W2890769616 endingPage "39" @default.
• W2890769616 startingPage "33" @default.
• W2890769616 abstract "Background Endovascular aneurysm repair (EVAR) accounts for the majority of all abdominal aortic aneurysm (AAA) repairs in the United States. EVAR utilization in the aging population is increasing due to the minimally invasive nature of the procedure, the low associated perioperative morbidity, and early survival benefit over open repair. The objective of this study is to compare the outcomes of octogenarians after elective EVAR to their younger counterparts, a question that can be answered by a long-term, institutional data set. Methods This was a retrospective series of 255 patients, who underwent elective EVAR within our institution from 2008 to 2015. A comparative analysis of patients aged 80 years and older and less than 80 years was performed. Outcomes measured included perioperative death and myocardial infarction (MI), length of stay, and readmission within 30 days. Aneurysm reintervention, long-term surveillance imaging, and aneurysm-related deaths were also evaluated. In addition, subset analyses of octogenarians were compared for survival at 24 months. Results Overall, 255 patients were included in our analysis. Fifty-nine patients were octogenarians, and 196 patients were nonoctogenarians. The mean age difference between the two groups was significant (84.5 years [SD, ±3.44] vs. 69.6 years [SD, ±6.13] in the ≥80 and <80 groups, respectively; P < 0.0001). There was no significant difference in the mean aneurysm size (6.03 cm [SD, ±1.12] vs. 5.535 cm [SD, ±0.9]; P < 0.06) between the ≥80 and < 80 groups. Octogenarians had higher rates of perioperative MI (5% vs. 1%, P < 0.04), thirty-day mortality (7% vs. 0%, P < 0.003), a higher number of perioperative complications (0.64 incidence per patient [SD, ±1.11] vs. 0.31 [SD, ±0.69], P < 0.005), and a longer mean hospital stay (5.34 [SD, ±5.75] days vs. 3.16 [SD, ±3.23] days, P < 0.0003), and they were also less likely to be discharged home after surgery (75% vs. 91%, P < 0.002). In the evaluated long-term outcomes, the two groups were similar with regard to aneurysm reintervention (10% vs. 9%, P < 0.06) and the stability of aneurysm sac size on imaging at last follow-up (71% vs. 80%, P < 0.27). The overall aortic related cause of death was different between the groups (8% vs. 1%, P < 0.003); however, the long-term aortic related mortality was not different between the two groups (2% vs. 1%, P < 0.4). Finally, a subset analysis of the octogenarian group was performed comparing patients based on survival status at 24 months. Higher preoperative creatinine (1.73 mg/dL [SD, ±1.54] vs. 1.15 mg/dL [SD, ±0.46]) and lower preoperative hematocrit (33.9% [SD, ±3.43] vs. 37.2% [SD, ±4.9]) along with number of perioperative complications (1.2 incidence per patient [SD, ±1.74] vs. 0.45 [SD, ±0.73]) were associated with death at 24 months after the index operation. Conclusions Elective endovascular repair of AAA in octogenarians carries a higher risk of perioperative mortality but acceptable long-term outcomes. Appropriateness of elective EVAR in octogenarians should be answered based on this potential short-lived survival benefit, taking into account that advanced age should not be the sole basis of exclusion for otherwise suitable candidates for elective EVAR. Endovascular aneurysm repair (EVAR) accounts for the majority of all abdominal aortic aneurysm (AAA) repairs in the United States. EVAR utilization in the aging population is increasing due to the minimally invasive nature of the procedure, the low associated perioperative morbidity, and early survival benefit over open repair. The objective of this study is to compare the outcomes of octogenarians after elective EVAR to their younger counterparts, a question that can be answered by a long-term, institutional data set. This was a retrospective series of 255 patients, who underwent elective EVAR within our institution from 2008 to 2015. A comparative analysis of patients aged 80 years and older and less than 80 years was performed. Outcomes measured included perioperative death and myocardial infarction (MI), length of stay, and readmission within 30 days. Aneurysm reintervention, long-term surveillance imaging, and aneurysm-related deaths were also evaluated. In addition, subset analyses of octogenarians were compared for survival at 24 months. Overall, 255 patients were included in our analysis. Fifty-nine patients were octogenarians, and 196 patients were nonoctogenarians. The mean age difference between the two groups was significant (84.5 years [SD, ±3.44] vs. 69.6 years [SD, ±6.13] in the ≥80 and <80 groups, respectively; P < 0.0001). There was no significant difference in the mean aneurysm size (6.03 cm [SD, ±1.12] vs. 5.535 cm [SD, ±0.9]; P < 0.06) between the ≥80 and < 80 groups. Octogenarians had higher rates of perioperative MI (5% vs. 1%, P < 0.04), thirty-day mortality (7% vs. 0%, P < 0.003), a higher number of perioperative complications (0.64 incidence per patient [SD, ±1.11] vs. 0.31 [SD, ±0.69], P < 0.005), and a longer mean hospital stay (5.34 [SD, ±5.75] days vs. 3.16 [SD, ±3.23] days, P < 0.0003), and they were also less likely to be discharged home after surgery (75% vs. 91%, P < 0.002). In the evaluated long-term outcomes, the two groups were similar with regard to aneurysm reintervention (10% vs. 9%, P < 0.06) and the stability of aneurysm sac size on imaging at last follow-up (71% vs. 80%, P < 0.27). The overall aortic related cause of death was different between the groups (8% vs. 1%, P < 0.003); however, the long-term aortic related mortality was not different between the two groups (2% vs. 1%, P < 0.4). Finally, a subset analysis of the octogenarian group was performed comparing patients based on survival status at 24 months. Higher preoperative creatinine (1.73 mg/dL [SD, ±1.54] vs. 1.15 mg/dL [SD, ±0.46]) and lower preoperative hematocrit (33.9% [SD, ±3.43] vs. 37.2% [SD, ±4.9]) along with number of perioperative complications (1.2 incidence per patient [SD, ±1.74] vs. 0.45 [SD, ±0.73]) were associated with death at 24 months after the index operation. Elective endovascular repair of AAA in octogenarians carries a higher risk of perioperative mortality but acceptable long-term outcomes. Appropriateness of elective EVAR in octogenarians should be answered based on this potential short-lived survival benefit, taking into account that advanced age should not be the sole basis of exclusion for otherwise suitable candidates for elective EVAR." @default.
• W2890769616 created "2018-09-27" @default.
• W2890769616 creator A5000655672 @default.
• W2890769616 creator A5013422671 @default.
• W2890769616 creator A5031410125 @default.
• W2890769616 creator A5047349393 @default.
• W2890769616 creator A5050754172 @default.
• W2890769616 creator A5082902839 @default.
• W2890769616 creator A5089196838 @default.
• W2890769616 creator A5090653681 @default.
• W2890769616 date "2019-01-01" @default.
• W2890769616 modified "2023-09-28" @default.
• W2890769616 title "Outcomes and Durability of Endovascular Aneurysm Repair in Octogenarians" @default.
• W2890769616 cites W1826558266 @default.
• W2890769616 cites W1986693759 @default.
• W2890769616 cites W1987182985 @default.
• W2890769616 cites W2010051381 @default.
• W2890769616 cites W2057697492 @default.
• W2890769616 cites W2132440079 @default.
• W2890769616 cites W2169814277 @default.
• W2890769616 cites W2460620964 @default.
• W2890769616 cites W2557617526 @default.
• W2890769616 cites W2714122290 @default.
• W2890769616 doi "https://doi.org/10.1016/j.avsg.2018.08.074" @default.
• W2890769616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30244017" @default.
• W2890769616 hasPublicationYear "2019" @default.
• W2890769616 type Work @default.
• W2890769616 sameAs 2890769616 @default.
• W2890769616 citedByCount "17" @default.
• W2890769616 countsByYear W28907696162019 @default.
• W2890769616 countsByYear W28907696162020 @default.
• W2890769616 countsByYear W28907696162021 @default.
• W2890769616 countsByYear W28907696162022 @default.
• W2890769616 countsByYear W28907696162023 @default.
• W2890769616 crossrefType "journal-article" @default.
• W2890769616 hasAuthorship W2890769616A5000655672 @default.
• W2890769616 hasAuthorship W2890769616A5013422671 @default.
• W2890769616 hasAuthorship W2890769616A5031410125 @default.
• W2890769616 hasAuthorship W2890769616A5047349393 @default.
• W2890769616 hasAuthorship W2890769616A5050754172 @default.
• W2890769616 hasAuthorship W2890769616A5082902839 @default.
• W2890769616 hasAuthorship W2890769616A5089196838 @default.
• W2890769616 hasAuthorship W2890769616A5090653681 @default.
• W2890769616 hasConcept C104304963 @default.
• W2890769616 hasConcept C126838900 @default.
• W2890769616 hasConcept C141071460 @default.
• W2890769616 hasConcept C2776098176 @default.
• W2890769616 hasConcept C2776543907 @default.
• W2890769616 hasConcept C2779993416 @default.
• W2890769616 hasConcept C2780120127 @default.
• W2890769616 hasConcept C41008148 @default.
• W2890769616 hasConcept C71924100 @default.
• W2890769616 hasConcept C77088390 @default.
• W2890769616 hasConceptScore W2890769616C104304963 @default.
• W2890769616 hasConceptScore W2890769616C126838900 @default.
• W2890769616 hasConceptScore W2890769616C141071460 @default.
• W2890769616 hasConceptScore W2890769616C2776098176 @default.
• W2890769616 hasConceptScore W2890769616C2776543907 @default.
• W2890769616 hasConceptScore W2890769616C2779993416 @default.
• W2890769616 hasConceptScore W2890769616C2780120127 @default.
• W2890769616 hasConceptScore W2890769616C41008148 @default.
• W2890769616 hasConceptScore W2890769616C71924100 @default.
• W2890769616 hasConceptScore W2890769616C77088390 @default.
• W2890769616 hasLocation W28907696161 @default.
• W2890769616 hasLocation W28907696162 @default.
• W2890769616 hasOpenAccess W2890769616 @default.
• W2890769616 hasPrimaryLocation W28907696161 @default.
• W2890769616 hasRelatedWork W2002398460 @default.
• W2890769616 hasRelatedWork W2003938723 @default.
• W2890769616 hasRelatedWork W2021250647 @default.
• W2890769616 hasRelatedWork W2047967234 @default.
• W2890769616 hasRelatedWork W2118496982 @default.
• W2890769616 hasRelatedWork W2139237756 @default.
• W2890769616 hasRelatedWork W2394922615 @default.
• W2890769616 hasRelatedWork W2439875401 @default.
• W2890769616 hasRelatedWork W4238867864 @default.
• W2890769616 hasRelatedWork W2525756941 @default.
• W2890769616 hasVolume "54" @default.
• W2890769616 isParatext "false" @default.
• W2890769616 isRetracted "false" @default.
• W2890769616 magId "2890769616" @default.
• W2890769616 workType "article" @default.