FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890774992> ?p ?o ?g. }

• W2890774992 endingPage "e201800086" @default.
• W2890774992 startingPage "e201800086" @default.
• W2890774992 abstract "Imaging of transcription by quantitative fluorescence-based techniques allows the examination of gene expression kinetics in single cells. Using a cell system for the in vivo visualization of mammalian mRNA transcriptional kinetics at single-gene resolution during the cell cycle, we previously demonstrated a reduction in transcription levels after replication. This phenomenon has been described as a homeostasis mechanism that buffers mRNA transcription levels with respect to the cell cycle stage and the number of transcribing alleles. Here, we examined how transcriptional buffering enforced during S phase affects two different promoters, the cytomegalovirus promoter versus the cyclin D1 promoter, that drive the same gene body. We found that global modulation of histone modifications could completely revert the transcription down-regulation imposed during replication. Furthermore, measuring these levels of transcriptional activity in fixed and living cells showed that the transcriptional potential of the genes was significantly higher than actual transcription levels, suggesting that promoters might normally be limited from reaching their full transcriptional potential." @default.
• W2890774992 created "2018-09-27" @default.
• W2890774992 creator A5002299903 @default.
• W2890774992 creator A5016816095 @default.
• W2890774992 creator A5037209358 @default.
• W2890774992 creator A5041684061 @default.
• W2890774992 creator A5063284395 @default.
• W2890774992 creator A5082934579 @default.
• W2890774992 creator A5091277711 @default.
• W2890774992 date "2018-09-19" @default.
• W2890774992 modified "2023-09-27" @default.
• W2890774992 title "S-phase transcriptional buffering quantified on two different promoters" @default.
• W2890774992 cites W1964076886 @default.
• W2890774992 cites W1992772703 @default.
• W2890774992 cites W2049222491 @default.
• W2890774992 cites W2049712743 @default.
• W2890774992 cites W2058414716 @default.
• W2890774992 cites W2069280583 @default.
• W2890774992 cites W2075865654 @default.
• W2890774992 cites W2078127732 @default.
• W2890774992 cites W2085020901 @default.
• W2890774992 cites W2100794056 @default.
• W2890774992 cites W2103354991 @default.
• W2890774992 cites W2108080167 @default.
• W2890774992 cites W2112238103 @default.
• W2890774992 cites W2127540003 @default.
• W2890774992 cites W2129218346 @default.
• W2890774992 cites W2131162901 @default.
• W2890774992 cites W2134977493 @default.
• W2890774992 cites W2135830745 @default.
• W2890774992 cites W2154026141 @default.
• W2890774992 cites W2185063486 @default.
• W2890774992 cites W2289395881 @default.
• W2890774992 cites W2290825831 @default.
• W2890774992 cites W2414634739 @default.
• W2890774992 cites W2502722983 @default.
• W2890774992 cites W2553330024 @default.
• W2890774992 cites W2784311345 @default.
• W2890774992 doi "https://doi.org/10.26508/lsa.201800086" @default.
• W2890774992 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6238621" @default.
• W2890774992 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30456379" @default.
• W2890774992 hasPublicationYear "2018" @default.
• W2890774992 type Work @default.
• W2890774992 sameAs 2890774992 @default.
• W2890774992 citedByCount "4" @default.
• W2890774992 countsByYear W28907749922019 @default.
• W2890774992 countsByYear W28907749922021 @default.
• W2890774992 countsByYear W28907749922023 @default.
• W2890774992 crossrefType "journal-article" @default.
• W2890774992 hasAuthorship W2890774992A5002299903 @default.
• W2890774992 hasAuthorship W2890774992A5016816095 @default.
• W2890774992 hasAuthorship W2890774992A5037209358 @default.
• W2890774992 hasAuthorship W2890774992A5041684061 @default.
• W2890774992 hasAuthorship W2890774992A5063284395 @default.
• W2890774992 hasAuthorship W2890774992A5082934579 @default.
• W2890774992 hasAuthorship W2890774992A5091277711 @default.
• W2890774992 hasBestOaLocation W28907749921 @default.
• W2890774992 hasConcept C101762097 @default.
• W2890774992 hasConcept C104317684 @default.
• W2890774992 hasConcept C138885662 @default.
• W2890774992 hasConcept C150194340 @default.
• W2890774992 hasConcept C153911025 @default.
• W2890774992 hasConcept C165864922 @default.
• W2890774992 hasConcept C179926584 @default.
• W2890774992 hasConcept C27153228 @default.
• W2890774992 hasConcept C29537977 @default.
• W2890774992 hasConcept C41895202 @default.
• W2890774992 hasConcept C54355233 @default.
• W2890774992 hasConcept C64350747 @default.
• W2890774992 hasConcept C86803240 @default.
• W2890774992 hasConcept C95444343 @default.
• W2890774992 hasConceptScore W2890774992C101762097 @default.
• W2890774992 hasConceptScore W2890774992C104317684 @default.
• W2890774992 hasConceptScore W2890774992C138885662 @default.
• W2890774992 hasConceptScore W2890774992C150194340 @default.
• W2890774992 hasConceptScore W2890774992C153911025 @default.
• W2890774992 hasConceptScore W2890774992C165864922 @default.
• W2890774992 hasConceptScore W2890774992C179926584 @default.
• W2890774992 hasConceptScore W2890774992C27153228 @default.
• W2890774992 hasConceptScore W2890774992C29537977 @default.
• W2890774992 hasConceptScore W2890774992C41895202 @default.
• W2890774992 hasConceptScore W2890774992C54355233 @default.
• W2890774992 hasConceptScore W2890774992C64350747 @default.
• W2890774992 hasConceptScore W2890774992C86803240 @default.
• W2890774992 hasConceptScore W2890774992C95444343 @default.
• W2890774992 hasFunder F4320322252 @default.
• W2890774992 hasIssue "5" @default.
• W2890774992 hasLocation W28907749921 @default.
• W2890774992 hasLocation W28907749922 @default.
• W2890774992 hasLocation W28907749923 @default.
• W2890774992 hasLocation W28907749924 @default.
• W2890774992 hasOpenAccess W2890774992 @default.
• W2890774992 hasPrimaryLocation W28907749921 @default.
• W2890774992 hasRelatedWork W1870486696 @default.
• W2890774992 hasRelatedWork W1971456303 @default.
• W2890774992 hasRelatedWork W1971823017 @default.
• W2890774992 hasRelatedWork W2062378380 @default.
• W2890774992 hasRelatedWork W2172226517 @default.

• next