FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890777887> ?p ?o ?g. }

• W2890777887 endingPage "271" @default.
• W2890777887 startingPage "260" @default.
• W2890777887 abstract "To assess the role of aberrant miRNAs expressions in stage II CRC patients from Egypt. Tumor tissue samples were obtained from 124 CRC stage II patients compared to 100 healthy controls for assessing miRNAs expression using; 1) a cataloged 84-miRNAs PCR array panel, and 2) another five miRNAs (miR-21, miR-137, miR-145, miR-320 and miR-498) that have been reported in previous studies to have a role in CRC, by quantitative real time PCR (qPCR). The results were correlated to patients' characteristics, response to treatment and survival. There were 17 out of 84 miRNAs differentially expressed in the CRC patients. Twenty six miRNAs were significantly differentially expressed in the female CRC patients, while 16 miRNAs were significantly differentially expressed in the male CRC patients. Only, five miRNAs (miR-21, Let-7a-5p, miR-100-5p, miR-200c-3p and miR-23b-3p) were significantly common deregulated in CRC patients regardless gender. miR-21 was overexpressed in 48.4% of the patients and it was significantly downregulated in females and over expressed in males. In univariate analysis; performance status, over-expression of miR-21 and miR-498 and reduced miR-137, miR-145, and miR-320 associated significantly with reduced DFS and OS whereas in multivariate analysis; miR-498 and miR-320 were independent prognostic factors for DFS and miR-21 was independent prognostic factors for OS. miRNAs expression differs significantly between male and female stage II CRC patients, miR-21, Let-7a-5p, miR-100-5p, miR-200c-3p and miR-23b-3p could be used as common diagnostic biomarkers for CRC. On the other hand, a three miRNAs panel (miR-21, miR-498 and miR-320) can predict recurrence and survival in those patients." @default.
• W2890777887 created "2018-09-27" @default.
• W2890777887 creator A5011550415 @default.
• W2890777887 creator A5014058991 @default.
• W2890777887 creator A5016320447 @default.
• W2890777887 creator A5024357259 @default.
• W2890777887 creator A5033406657 @default.
• W2890777887 creator A5034000985 @default.
• W2890777887 creator A5040498831 @default.
• W2890777887 creator A5043852977 @default.
• W2890777887 creator A5047078549 @default.
• W2890777887 creator A5084237815 @default.
• W2890777887 date "2018-12-01" @default.
• W2890777887 modified "2023-10-10" @default.
• W2890777887 title "MiRNAs as molecular biomarkers in stage II egyptian colorectal cancer patients" @default.
• W2890777887 cites W1512280165 @default.
• W2890777887 cites W1942770734 @default.
• W2890777887 cites W1966801430 @default.
• W2890777887 cites W1968036181 @default.
• W2890777887 cites W1986222782 @default.
• W2890777887 cites W2009921262 @default.
• W2890777887 cites W2010449259 @default.
• W2890777887 cites W2015423537 @default.
• W2890777887 cites W2016024700 @default.
• W2890777887 cites W2019663969 @default.
• W2890777887 cites W2022013872 @default.
• W2890777887 cites W2035213975 @default.
• W2890777887 cites W2039606711 @default.
• W2890777887 cites W2047096041 @default.
• W2890777887 cites W2050079849 @default.
• W2890777887 cites W2055489631 @default.
• W2890777887 cites W2056185445 @default.
• W2890777887 cites W2062206928 @default.
• W2890777887 cites W2065302641 @default.
• W2890777887 cites W2074404635 @default.
• W2890777887 cites W2078948671 @default.
• W2890777887 cites W2113551318 @default.
• W2890777887 cites W2122014435 @default.
• W2890777887 cites W2135007926 @default.
• W2890777887 cites W2135810600 @default.
• W2890777887 cites W2165616810 @default.
• W2890777887 cites W2219573808 @default.
• W2890777887 cites W2339130670 @default.
• W2890777887 cites W2736447228 @default.
• W2890777887 cites W2743116197 @default.
• W2890777887 cites W2755159617 @default.
• W2890777887 cites W2768740980 @default.
• W2890777887 cites W2917837889 @default.
• W2890777887 cites W4379438136 @default.
• W2890777887 doi "https://doi.org/10.1016/j.yexmp.2018.09.002" @default.
• W2890777887 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30213464" @default.
• W2890777887 hasPublicationYear "2018" @default.
• W2890777887 type Work @default.
• W2890777887 sameAs 2890777887 @default.
• W2890777887 citedByCount "11" @default.
• W2890777887 countsByYear W28907778872020 @default.
• W2890777887 countsByYear W28907778872021 @default.
• W2890777887 countsByYear W28907778872022 @default.
• W2890777887 countsByYear W28907778872023 @default.
• W2890777887 crossrefType "journal-article" @default.
• W2890777887 hasAuthorship W2890777887A5011550415 @default.
• W2890777887 hasAuthorship W2890777887A5014058991 @default.
• W2890777887 hasAuthorship W2890777887A5016320447 @default.
• W2890777887 hasAuthorship W2890777887A5024357259 @default.
• W2890777887 hasAuthorship W2890777887A5033406657 @default.
• W2890777887 hasAuthorship W2890777887A5034000985 @default.
• W2890777887 hasAuthorship W2890777887A5040498831 @default.
• W2890777887 hasAuthorship W2890777887A5043852977 @default.
• W2890777887 hasAuthorship W2890777887A5047078549 @default.
• W2890777887 hasAuthorship W2890777887A5084237815 @default.
• W2890777887 hasConcept C104317684 @default.
• W2890777887 hasConcept C121608353 @default.
• W2890777887 hasConcept C126322002 @default.
• W2890777887 hasConcept C143998085 @default.
• W2890777887 hasConcept C144301174 @default.
• W2890777887 hasConcept C145059251 @default.
• W2890777887 hasConcept C146357865 @default.
• W2890777887 hasConcept C151730666 @default.
• W2890777887 hasConcept C38180746 @default.
• W2890777887 hasConcept C48023723 @default.
• W2890777887 hasConcept C502942594 @default.
• W2890777887 hasConcept C526805850 @default.
• W2890777887 hasConcept C54355233 @default.
• W2890777887 hasConcept C71924100 @default.
• W2890777887 hasConcept C86803240 @default.
• W2890777887 hasConceptScore W2890777887C104317684 @default.
• W2890777887 hasConceptScore W2890777887C121608353 @default.
• W2890777887 hasConceptScore W2890777887C126322002 @default.
• W2890777887 hasConceptScore W2890777887C143998085 @default.
• W2890777887 hasConceptScore W2890777887C144301174 @default.
• W2890777887 hasConceptScore W2890777887C145059251 @default.
• W2890777887 hasConceptScore W2890777887C146357865 @default.
• W2890777887 hasConceptScore W2890777887C151730666 @default.
• W2890777887 hasConceptScore W2890777887C38180746 @default.
• W2890777887 hasConceptScore W2890777887C48023723 @default.
• W2890777887 hasConceptScore W2890777887C502942594 @default.
• W2890777887 hasConceptScore W2890777887C526805850 @default.
• W2890777887 hasConceptScore W2890777887C54355233 @default.

• next