FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890790670> ?p ?o ?g. }

• W2890790670 endingPage "150" @default.
• W2890790670 startingPage "131" @default.
• W2890790670 abstract "The cardiac extracellular matrix (cECM) is comprised of proteins and polysaccharides secreted by cardiac cell types, which provide structural and biochemical support to cardiovascular tissue. The roles of cECM proteins and the associated family of cell surface receptor, integrins, have been explored in vivo via the generation of knockout experimental animal models. However, the complexity of tissues makes it difficult to isolate the effects of individual cECM proteins on a particular cell process or disease state. The desire to further dissect the role of cECM has led to the development of a variety of in vitro model systems, which are now being used not only for basic studies but also for testing drug efficacy and toxicity and for generating therapeutic scaffolds. These systems began with 2D coatings of cECM derived from tissue and have developed to include recombinant ECM proteins, ECM fragments, and ECM mimics. Most recently 3D model systems have emerged, made possible by several developing technologies including, and most notably, 3D bioprinting. This chapter will attempt to track the evolution of our understanding of the relationship between cECM and cell behavior from in vivo model to in vitro control systems. We end the chapter with a summary of how basic studies such as these have informed the use of cECM as a direct therapy." @default.
• W2890790670 created "2018-09-27" @default.
• W2890790670 creator A5005862051 @default.
• W2890790670 creator A5082090157 @default.
• W2890790670 date "2018-01-01" @default.
• W2890790670 modified "2023-09-25" @default.
• W2890790670 title "Cardiac Extracellular Matrix Modification as a Therapeutic Approach" @default.
• W2890790670 cites W1423628101 @default.
• W2890790670 cites W1521943995 @default.
• W2890790670 cites W1653019055 @default.
• W2890790670 cites W1818943734 @default.
• W2890790670 cites W1858195685 @default.
• W2890790670 cites W1966857509 @default.
• W2890790670 cites W1967807152 @default.
• W2890790670 cites W1969741234 @default.
• W2890790670 cites W1978918367 @default.
• W2890790670 cites W1990683187 @default.
• W2890790670 cites W1992604504 @default.
• W2890790670 cites W1992918189 @default.
• W2890790670 cites W1995572821 @default.
• W2890790670 cites W1996150537 @default.
• W2890790670 cites W2002178288 @default.
• W2890790670 cites W2003095278 @default.
• W2890790670 cites W2006508505 @default.
• W2890790670 cites W2007279845 @default.
• W2890790670 cites W2009290897 @default.
• W2890790670 cites W2009710644 @default.
• W2890790670 cites W2011907701 @default.
• W2890790670 cites W2017105523 @default.
• W2890790670 cites W2024236584 @default.
• W2890790670 cites W2027023682 @default.
• W2890790670 cites W2031203524 @default.
• W2890790670 cites W2031935322 @default.
• W2890790670 cites W2042706188 @default.
• W2890790670 cites W2046616627 @default.
• W2890790670 cites W2047524138 @default.
• W2890790670 cites W2050382572 @default.
• W2890790670 cites W2050852585 @default.
• W2890790670 cites W2052215721 @default.
• W2890790670 cites W2059989280 @default.
• W2890790670 cites W2066425292 @default.
• W2890790670 cites W2073016513 @default.
• W2890790670 cites W2075166318 @default.
• W2890790670 cites W2075285089 @default.
• W2890790670 cites W2075665113 @default.
• W2890790670 cites W2079738970 @default.
• W2890790670 cites W2079855910 @default.
• W2890790670 cites W2084533380 @default.
• W2890790670 cites W2090028890 @default.
• W2890790670 cites W2096252197 @default.
• W2890790670 cites W2098327618 @default.
• W2890790670 cites W2104121252 @default.
• W2890790670 cites W2118522871 @default.
• W2890790670 cites W2122439421 @default.
• W2890790670 cites W2125232792 @default.
• W2890790670 cites W2128754233 @default.
• W2890790670 cites W2131677262 @default.
• W2890790670 cites W2133683725 @default.
• W2890790670 cites W2134272331 @default.
• W2890790670 cites W2135241125 @default.
• W2890790670 cites W2143156113 @default.
• W2890790670 cites W2146883625 @default.
• W2890790670 cites W2152029916 @default.
• W2890790670 cites W2154840648 @default.
• W2890790670 cites W2158251337 @default.
• W2890790670 cites W2165162823 @default.
• W2890790670 cites W2165830630 @default.
• W2890790670 cites W2171925711 @default.
• W2890790670 cites W2188422153 @default.
• W2890790670 cites W2224089124 @default.
• W2890790670 cites W2252659026 @default.
• W2890790670 cites W2256191215 @default.
• W2890790670 cites W2276218663 @default.
• W2890790670 cites W2277025359 @default.
• W2890790670 cites W2294836384 @default.
• W2890790670 cites W2299693612 @default.
• W2890790670 cites W2324587488 @default.
• W2890790670 cites W2331507242 @default.
• W2890790670 cites W2346423678 @default.
• W2890790670 cites W2362125499 @default.
• W2890790670 cites W2404682075 @default.
• W2890790670 cites W2418955432 @default.
• W2890790670 cites W2475398943 @default.
• W2890790670 cites W2517113285 @default.
• W2890790670 cites W2546763758 @default.
• W2890790670 cites W2568319444 @default.
• W2890790670 cites W2573540928 @default.
• W2890790670 cites W2626725994 @default.
• W2890790670 cites W3190496831 @default.
• W2890790670 cites W403738358 @default.
• W2890790670 cites W48830290 @default.
• W2890790670 cites W76931516 @default.
• W2890790670 doi "https://doi.org/10.1007/978-3-319-97421-7_7" @default.
• W2890790670 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6584040" @default.
• W2890790670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30238369" @default.
• W2890790670 hasPublicationYear "2018" @default.
• W2890790670 type Work @default.
• W2890790670 sameAs 2890790670 @default.

• next