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- W2890825510 abstract "The goal of this study was to highlight the usefulness of fluorine-18-fluorodeoxyglucose-positron emission tomography/computed tomography (18-F-FDG PET/CT) in soft tissue sarcoma (STS) follow-up to distinguish fibrosis from residual/recurring viable tumours and to detect distant metastases. Twenty-three patients with confirmed STS underwent PET/CT scans. Bone and visceral sarcomas were excluded. Detailed case-based and statistical analyses were performed. Final diagnosis was confirmed by clinical or radiological examination and/or biopsy. The most common pathological diagnoses were synovial sarcomas (26.1%). PET/CT detected local disease recurrence in 8 cases. True positives for local disease were detected in 6 cases, and false negatives occurred in 2 cases (well-differentiated liposarcoma and low-grade synovial sarcoma). Distant disease was negative in 14/23 cases, and 2 cases were false negatives. Overall, PET/CT had 80% sensitivity, 87.5% specificity, 92.3% PPV, 70% NPV and 82.6% accuracy in STS treatment response follow-up. 18-F-FDG PET/CT is a useful imaging modality for STS follow-up and is effective in guiding biopsies. Locoregional and distant metastatic spread can be detected using PET/CT, with some limitations." @default.
- W2890825510 created "2018-09-27" @default.
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- W2890825510 date "2018-12-01" @default.
- W2890825510 modified "2023-09-27" @default.
- W2890825510 title "The usefulness of 18-F-FDG PET/CT for detection of adult soft tissue sarcomas local recurrence and distant metastases" @default.
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- W2890825510 doi "https://doi.org/10.1016/j.ejrnm.2018.05.014" @default.
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