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• W2890827307 endingPage "1172" @default.
• W2890827307 startingPage "1172" @default.
• W2890827307 abstract "Overweight and obesity have been associated with adverse health effects.To systematically review evidence on benefits and harms of behavioral and pharmacotherapy weight loss and weight loss maintenance interventions in adults to inform the US Preventive Services Task Force.MEDLINE, PubMed Publisher-Supplied Records, PsycINFO, and the Cochrane Central Register of Controlled Trials for studies published through June 6, 2017; ClinicalTrials.gov and the World Health Organization International Clinical Trials Registry Platform for ongoing trials through August 2017; and ongoing surveillance in targeted publications through March 23, 2018. Studies from previous reviews were reevaluated for inclusion.Randomized clinical trials (RCTs) focusing on weight loss or weight loss maintenance in adults.Data were abstracted by one reviewer and confirmed by another. Random-effects meta-analyses were conducted for weight loss outcomes in behavior-based interventions.Health outcomes, weight loss or weight loss maintenance, reduction in obesity-related conditions, and adverse events.A total of 122 RCTs (N = 62 533) and 2 observational studies (N = 209 993) were identified. Compared with controls, participants in behavior-based interventions had greater mean weight loss at 12 to 18 months (-2.39 kg [95% CI, -2.86 to -1.93]; 67 studies [n = 22065]) and less weight regain (-1.59 kg [95% CI, -2.38 to -0.79]; 8 studies [n = 1408]). Studies of medication-based weight loss and maintenance interventions also reported greater weight loss or less weight regain in intervention compared with placebo groups at 12 to 18 months (range, -0.6 to -5.8 kg; no meta-analysis). Participants with prediabetes in weight loss interventions had a lower risk of developing diabetes compared with controls (relative risk, 0.67 [95% CI, 0.51 to 0.89]). There was no evidence of other benefits, but most health outcomes such as mortality, cardiovascular disease, and cancer were infrequently reported. Small improvements in quality of life in some medication trials were noted but were of unclear clinical significance. There was no evidence of harm such as cardiovascular disease from behavior-based interventions; higher rates of adverse events were associated with higher dropout rates in medication groups than in placebo groups.Behavior-based weight loss interventions with or without weight loss medications were associated with more weight loss and a lower risk of developing diabetes than control conditions. Weight loss medications, but not behavior-based interventions, were associated with higher rates of harms. Long-term weight and health outcomes data, as well as data on important subgroups, were limited." @default.
• W2890827307 created "2018-09-27" @default.
• W2890827307 creator A5018860390 @default.
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• W2890827307 date "2018-09-18" @default.
• W2890827307 modified "2023-10-10" @default.
• W2890827307 title "Behavioral and Pharmacotherapy Weight Loss Interventions to Prevent Obesity-Related Morbidity and Mortality in Adults" @default.
• W2890827307 cites W1486736119 @default.
• W2890827307 cites W1513833217 @default.
• W2890827307 cites W1526958062 @default.
• W2890827307 cites W1537391465 @default.
• W2890827307 cites W1540336178 @default.
• W2890827307 cites W1542051532 @default.
• W2890827307 cites W1591686206 @default.
• W2890827307 cites W167057333 @default.
• W2890827307 cites W1808854999 @default.
• W2890827307 cites W1921124913 @default.
• W2890827307 cites W1936710697 @default.
• W2890827307 cites W1941934316 @default.
• W2890827307 cites W1956486731 @default.
• W2890827307 cites W1958859967 @default.
• W2890827307 cites W1959519160 @default.
• W2890827307 cites W1964227153 @default.
• W2890827307 cites W1964821956 @default.
• W2890827307 cites W1967237278 @default.
• W2890827307 cites W1970792997 @default.
• W2890827307 cites W1970837110 @default.
• W2890827307 cites W1974942855 @default.
• W2890827307 cites W1979269807 @default.
• W2890827307 cites W1980078112 @default.
• W2890827307 cites W1980416307 @default.
• W2890827307 cites W1980641839 @default.
• W2890827307 cites W1981309817 @default.
• W2890827307 cites W1982161695 @default.
• W2890827307 cites W1983876438 @default.
• W2890827307 cites W1987593352 @default.
• W2890827307 cites W1988280850 @default.
• W2890827307 cites W1993149483 @default.
• W2890827307 cites W1993214259 @default.
• W2890827307 cites W1994014704 @default.
• W2890827307 cites W1994320162 @default.
• W2890827307 cites W1996069915 @default.
• W2890827307 cites W1997115741 @default.
• W2890827307 cites W1997683054 @default.
• W2890827307 cites W1998164017 @default.
• W2890827307 cites W1998451170 @default.
• W2890827307 cites W2003400880 @default.
• W2890827307 cites W2006138699 @default.
• W2890827307 cites W2006568353 @default.
• W2890827307 cites W2008526478 @default.
• W2890827307 cites W2014411813 @default.
• W2890827307 cites W2014968248 @default.
• W2890827307 cites W2015625684 @default.
• W2890827307 cites W2015788437 @default.
• W2890827307 cites W2022832100 @default.
• W2890827307 cites W2022924693 @default.
• W2890827307 cites W2023787398 @default.
• W2890827307 cites W2025227115 @default.
• W2890827307 cites W2025291237 @default.
• W2890827307 cites W2025566560 @default.
• W2890827307 cites W2026216536 @default.
• W2890827307 cites W2027834798 @default.
• W2890827307 cites W2028913390 @default.
• W2890827307 cites W2029664864 @default.
• W2890827307 cites W2030141899 @default.
• W2890827307 cites W2030142553 @default.
• W2890827307 cites W2034036388 @default.
• W2890827307 cites W2037116247 @default.
• W2890827307 cites W2038623844 @default.
• W2890827307 cites W2040895889 @default.
• W2890827307 cites W2042036345 @default.
• W2890827307 cites W2044964910 @default.
• W2890827307 cites W2048879830 @default.
• W2890827307 cites W2049518146 @default.
• W2890827307 cites W2051150556 @default.
• W2890827307 cites W2051528871 @default.
• W2890827307 cites W2055427786 @default.
• W2890827307 cites W2057818811 @default.
• W2890827307 cites W2058436463 @default.
• W2890827307 cites W2062892362 @default.
• W2890827307 cites W2065022170 @default.
• W2890827307 cites W2065732781 @default.
• W2890827307 cites W2069454730 @default.
• W2890827307 cites W2069584230 @default.
• W2890827307 cites W2069680000 @default.
• W2890827307 cites W2070415982 @default.
• W2890827307 cites W2071411038 @default.
• W2890827307 cites W2074571888 @default.
• W2890827307 cites W2075956298 @default.
• W2890827307 cites W2080841410 @default.
• W2890827307 cites W2080953758 @default.
• W2890827307 cites W2081027346 @default.
• W2890827307 cites W2081289399 @default.
• W2890827307 cites W2084049865 @default.

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