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- W2890835629 abstract "Background Perforation is the most common surgical complication in pediatric intestinal lymphoma. During operation, many surgical decisions are debatable. Aim To assess the outcome of surgical management of perforated pediatric intestinal lymphoma. Patients and methods This is a retrospective analysis of all pediatric patients (<18 years old) with intestinal lymphoma treated in our hospital between July 2007 and June 2017. Risk factors for perforation, type of management and outcome in cases of intestinal perforation were analyzed. Results The study included 240 patients with intestinal lymphoma. Perforation developed in 16 patients (6.7%) with a median age of 5.3 (range: 2.8–15.7) years. Most of the patients (92.5%) had Burkitt lymphoma. The ileum was the most common site of perforation (n = 10). Perforation occurred at presentation (n = 2), during induction (n = 10), during maintenance chemotherapy (n = 2), or at relapse (n = 2). Primary resection anastomosis was done in 12 patients. The resected specimen showed a viable tumor in ten patients. Wound infection (25%) and dehiscence (12.5%) were the most common postoperative complications. The 5-year overall and event-free survivals of patients with perforation were 78.6% and 71.4%, respectively, compared with 85.5% and 81.2% in non-perforated patients; the difference was not significant (p = 0.374 and p = 0.270, respectively). Conclusion Perforation is not an adverse prognostic factor for survival in pediatric intestinal lymphoma patients. Primary resection anastomosis seems to be a safe option if complete tumor resection is feasible." @default.
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- W2890835629 date "2019-02-01" @default.
- W2890835629 modified "2023-10-15" @default.
- W2890835629 title "Surgery in perforated pediatric intestinal lymphoma" @default.
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- W2890835629 doi "https://doi.org/10.1016/j.ejso.2018.08.022" @default.
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