Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890847557> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2890847557 abstract "Background/Objective: The present article is between the fewest that describe the expression of desmosomal proteins in human tooth organ and to implicate desmosome and its components in tooth morphogenesis. Although present in all epithelia, desmosomes are particularly down regulated in undifferentiated, dedifferentiated and malignant cells. Methodology: In the present article, using immunohistochemical staining, we report the expression patterns of 6 desmosomal components; Desmoplakin, plakoglobin, desmoglein, plakophilin-1, plakophilin-2, and plakophilin-3. The dental, oral and ectodermal epithelia were investigated in 7 and 9 weeks' human embryos. Results: The expression of these components appeared to associate with cell differentiation, stage of development and epithelial type. The fundamental desmosomal proteins, desmoplakin, plakoglobin and desmoglein, produced almost identical profiles, suggesting that desmosomes are absent or under developed in negative and weak reacting areas respectively. Whilst the accessory component plakophilin-1 was always absent, plakophilin-2 and -3 were strongly labeled in the embryonic epidermis and moderately expressed in the oral epithelium. In the developing enamel organ, gradients of fundamental protein expressions were produced being strong towards the oral epithelium and weak/negative around the inner enamel epithelium. These gradients were also produced using antibodies to plakophilin-2 and -3 although the majority of enamel organ cells were unlabeled. Conclusion: Mirror image symmetry was foundwas found for the distribution patterns of these markers. Furthermore, the left-right asymmetry was found both for the maxillary and mandibular tooth germs, thus bringing further evidence implicating desmosome and its components in the mechanisms regulating tooth morphogenesis." @default.
- W2890847557 created "2018-09-27" @default.
- W2890847557 creator A5012524603 @default.
- W2890847557 date "2018-01-01" @default.
- W2890847557 modified "2023-09-26" @default.
- W2890847557 title "Expression of desmosomal proteins and their implications during enamel organ morphogenesis" @default.
- W2890847557 doi "https://doi.org/10.4103/ijds.ijds_121_17" @default.
- W2890847557 hasPublicationYear "2018" @default.
- W2890847557 type Work @default.
- W2890847557 sameAs 2890847557 @default.
- W2890847557 citedByCount "0" @default.
- W2890847557 crossrefType "journal-article" @default.
- W2890847557 hasAuthorship W2890847557A5012524603 @default.
- W2890847557 hasBestOaLocation W28908475571 @default.
- W2890847557 hasConcept C104317684 @default.
- W2890847557 hasConcept C104392178 @default.
- W2890847557 hasConcept C105702510 @default.
- W2890847557 hasConcept C137620995 @default.
- W2890847557 hasConcept C142724271 @default.
- W2890847557 hasConcept C1491633281 @default.
- W2890847557 hasConcept C149402561 @default.
- W2890847557 hasConcept C156887251 @default.
- W2890847557 hasConcept C159654299 @default.
- W2890847557 hasConcept C163764329 @default.
- W2890847557 hasConcept C176860957 @default.
- W2890847557 hasConcept C199343813 @default.
- W2890847557 hasConcept C203014093 @default.
- W2890847557 hasConcept C2777189754 @default.
- W2890847557 hasConcept C2778757060 @default.
- W2890847557 hasConcept C2910519024 @default.
- W2890847557 hasConcept C30145163 @default.
- W2890847557 hasConcept C40692019 @default.
- W2890847557 hasConcept C48220470 @default.
- W2890847557 hasConcept C529295009 @default.
- W2890847557 hasConcept C54355233 @default.
- W2890847557 hasConcept C62478195 @default.
- W2890847557 hasConcept C67326383 @default.
- W2890847557 hasConcept C71924100 @default.
- W2890847557 hasConcept C86803240 @default.
- W2890847557 hasConcept C95444343 @default.
- W2890847557 hasConceptScore W2890847557C104317684 @default.
- W2890847557 hasConceptScore W2890847557C104392178 @default.
- W2890847557 hasConceptScore W2890847557C105702510 @default.
- W2890847557 hasConceptScore W2890847557C137620995 @default.
- W2890847557 hasConceptScore W2890847557C142724271 @default.
- W2890847557 hasConceptScore W2890847557C1491633281 @default.
- W2890847557 hasConceptScore W2890847557C149402561 @default.
- W2890847557 hasConceptScore W2890847557C156887251 @default.
- W2890847557 hasConceptScore W2890847557C159654299 @default.
- W2890847557 hasConceptScore W2890847557C163764329 @default.
- W2890847557 hasConceptScore W2890847557C176860957 @default.
- W2890847557 hasConceptScore W2890847557C199343813 @default.
- W2890847557 hasConceptScore W2890847557C203014093 @default.
- W2890847557 hasConceptScore W2890847557C2777189754 @default.
- W2890847557 hasConceptScore W2890847557C2778757060 @default.
- W2890847557 hasConceptScore W2890847557C2910519024 @default.
- W2890847557 hasConceptScore W2890847557C30145163 @default.
- W2890847557 hasConceptScore W2890847557C40692019 @default.
- W2890847557 hasConceptScore W2890847557C48220470 @default.
- W2890847557 hasConceptScore W2890847557C529295009 @default.
- W2890847557 hasConceptScore W2890847557C54355233 @default.
- W2890847557 hasConceptScore W2890847557C62478195 @default.
- W2890847557 hasConceptScore W2890847557C67326383 @default.
- W2890847557 hasConceptScore W2890847557C71924100 @default.
- W2890847557 hasConceptScore W2890847557C86803240 @default.
- W2890847557 hasConceptScore W2890847557C95444343 @default.
- W2890847557 hasLocation W28908475571 @default.
- W2890847557 hasOpenAccess W2890847557 @default.
- W2890847557 hasPrimaryLocation W28908475571 @default.
- W2890847557 hasRelatedWork W1966530704 @default.
- W2890847557 hasRelatedWork W1967509370 @default.
- W2890847557 hasRelatedWork W1978049780 @default.
- W2890847557 hasRelatedWork W1978939359 @default.
- W2890847557 hasRelatedWork W2009144650 @default.
- W2890847557 hasRelatedWork W2028002024 @default.
- W2890847557 hasRelatedWork W2034322759 @default.
- W2890847557 hasRelatedWork W2035558702 @default.
- W2890847557 hasRelatedWork W2043437287 @default.
- W2890847557 hasRelatedWork W2077890930 @default.
- W2890847557 hasRelatedWork W2083960895 @default.
- W2890847557 hasRelatedWork W2092743129 @default.
- W2890847557 hasRelatedWork W2099969886 @default.
- W2890847557 hasRelatedWork W2166191977 @default.
- W2890847557 hasRelatedWork W2290339819 @default.
- W2890847557 hasRelatedWork W2400206936 @default.
- W2890847557 hasRelatedWork W2412130875 @default.
- W2890847557 hasRelatedWork W32947050 @default.
- W2890847557 hasRelatedWork W346154027 @default.
- W2890847557 hasRelatedWork W67265543 @default.
- W2890847557 isParatext "false" @default.
- W2890847557 isRetracted "false" @default.
- W2890847557 magId "2890847557" @default.
- W2890847557 workType "article" @default.