Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890852480> ?p ?o ?g. }
- W2890852480 abstract "Familial Hypercholesterolemia (FH) is characterized by elevated cholesterol; this is based on biochemical, clinical, and genetic studies and FH disease, which was documented even with limited mutations. Earlier studies were associated with Apolipoprotein E (ApoE) in variable diseases. The current study aims to investigate the genetic association between FH disease and ApoE gene (rs429358 and rs7412) in the Saudi population. This study has been carried out as a case-control and is a hospital-based study in Saudi Arabia. Two hundred and four subjects were recruited as FH participants (n=104) and the others as controls (n=100). Common polymorphisms (rs429358 and rs7412) were selected from the ApoE gene and we then performed the genotyping as the TaqMan assay. Moreover, the ApoE risk allele E4 is significantly associated in FH cases and controls (OR-2.24 (95%CI: 1.06-4.70); p=0.02). Lipid profile parameters were significantly associated (p<0.05); however, a combination of ApoE alleles and lipid profiles could not find a correlation (p>0.05). The FH case-control study was associated with the E4 allele in the Saudi population. The risk of allele E4 which is a reliable marker for lipid profiles, but did not correlate with ApoE alleles." @default.
- W2890852480 created "2018-09-27" @default.
- W2890852480 creator A5010681002 @default.
- W2890852480 creator A5035660553 @default.
- W2890852480 creator A5056748152 @default.
- W2890852480 creator A5058319919 @default.
- W2890852480 creator A5062964123 @default.
- W2890852480 creator A5089162678 @default.
- W2890852480 date "2018-09-15" @default.
- W2890852480 modified "2023-10-15" @default.
- W2890852480 title "Role of Apolipoprotein E gene polymorphism in the risk of familial hypercholesterolemia: a case-control study" @default.
- W2890852480 cites W124853917 @default.
- W2890852480 cites W1425151805 @default.
- W2890852480 cites W1724544532 @default.
- W2890852480 cites W1815818861 @default.
- W2890852480 cites W1883718947 @default.
- W2890852480 cites W1928064044 @default.
- W2890852480 cites W1964352797 @default.
- W2890852480 cites W1964747908 @default.
- W2890852480 cites W1965301360 @default.
- W2890852480 cites W1972995116 @default.
- W2890852480 cites W1977511373 @default.
- W2890852480 cites W1979170611 @default.
- W2890852480 cites W1991306495 @default.
- W2890852480 cites W1993634977 @default.
- W2890852480 cites W2000379889 @default.
- W2890852480 cites W2005092604 @default.
- W2890852480 cites W2008962909 @default.
- W2890852480 cites W2009009921 @default.
- W2890852480 cites W2010083247 @default.
- W2890852480 cites W2011926011 @default.
- W2890852480 cites W2011987261 @default.
- W2890852480 cites W2021889162 @default.
- W2890852480 cites W2042103448 @default.
- W2890852480 cites W2049619885 @default.
- W2890852480 cites W2051882044 @default.
- W2890852480 cites W2057750496 @default.
- W2890852480 cites W2061028890 @default.
- W2890852480 cites W2066426139 @default.
- W2890852480 cites W2073308954 @default.
- W2890852480 cites W2074200940 @default.
- W2890852480 cites W2074627784 @default.
- W2890852480 cites W2075011933 @default.
- W2890852480 cites W2075467558 @default.
- W2890852480 cites W2087689337 @default.
- W2890852480 cites W2100352364 @default.
- W2890852480 cites W2103612899 @default.
- W2890852480 cites W2116451199 @default.
- W2890852480 cites W2118204583 @default.
- W2890852480 cites W2120043292 @default.
- W2890852480 cites W2126018548 @default.
- W2890852480 cites W2132981035 @default.
- W2890852480 cites W2135455133 @default.
- W2890852480 cites W2139565390 @default.
- W2890852480 cites W2140018799 @default.
- W2890852480 cites W2143895301 @default.
- W2890852480 cites W2145622300 @default.
- W2890852480 cites W2146922855 @default.
- W2890852480 cites W2167042818 @default.
- W2890852480 cites W2189189168 @default.
- W2890852480 cites W2194224017 @default.
- W2890852480 cites W2278072062 @default.
- W2890852480 cites W2280831439 @default.
- W2890852480 cites W2293730874 @default.
- W2890852480 cites W2322427743 @default.
- W2890852480 cites W2330131298 @default.
- W2890852480 cites W2336024501 @default.
- W2890852480 cites W2336425722 @default.
- W2890852480 cites W2336993245 @default.
- W2890852480 cites W2346299663 @default.
- W2890852480 cites W2408718933 @default.
- W2890852480 cites W2408861349 @default.
- W2890852480 cites W2423809522 @default.
- W2890852480 cites W2468739657 @default.
- W2890852480 cites W2478529323 @default.
- W2890852480 cites W2498995004 @default.
- W2890852480 cites W2506193900 @default.
- W2890852480 cites W2517352239 @default.
- W2890852480 cites W2523564199 @default.
- W2890852480 cites W253324400 @default.
- W2890852480 cites W2553648370 @default.
- W2890852480 cites W2608759280 @default.
- W2890852480 cites W2625750911 @default.
- W2890852480 cites W2730434210 @default.
- W2890852480 cites W2737597556 @default.
- W2890852480 cites W2801700336 @default.
- W2890852480 cites W365529033 @default.
- W2890852480 cites W48025246 @default.
- W2890852480 cites W2081763041 @default.
- W2890852480 cites W2101604925 @default.
- W2890852480 doi "https://doi.org/10.18388/abp.2017_2344" @default.
- W2890852480 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30235358" @default.
- W2890852480 hasPublicationYear "2018" @default.
- W2890852480 type Work @default.
- W2890852480 sameAs 2890852480 @default.
- W2890852480 citedByCount "5" @default.
- W2890852480 countsByYear W28908524802021 @default.
- W2890852480 countsByYear W28908524802022 @default.
- W2890852480 countsByYear W28908524802023 @default.
- W2890852480 crossrefType "journal-article" @default.