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- W2890854009 abstract "This two-year-old previously healthy girl presented with seizures and severe septic shock. She had fever, upper respiratory tract symptoms, and progressive alteration of mental status. Examination revealed a comatose, intubated child with generalized edema, abdominal distension, hepatosplenomegaly, and diffuse petechial rash. Her evaluation was significant for pancytopenia, coagulopathy, hypertriglyceridemia, and elevated ferritin. Cerebrospinal fluid contained 24 white blood cells with many immature mononuclear cells and high protein of 277 mg/dL. Her initial computed tomography scan was normal, but magnetic resonance imaging (MRI) showed large mass-like lesions in both frontal-parietal regions (Fig) with compression of the posterior horn of the left lateral ventricle. Bone marrow biopsy was consistent with a diagnosis of hemophagocytic lymphohistiocytosis (HLH). She survived the initial treatment phase with an improvement in her neurocognitive status and continued to receive a combined chemo-immunotherapy regimen." @default.
- W2890854009 created "2018-09-27" @default.
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- W2890854009 date "2018-12-01" @default.
- W2890854009 modified "2023-10-14" @default.
- W2890854009 title "Mass-Like Lesion on Brain Magnetic Resonance Imaging" @default.
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- W2890854009 doi "https://doi.org/10.1016/j.pediatrneurol.2018.09.003" @default.
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