Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890857439> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2890857439 endingPage "1158" @default.
- W2890857439 startingPage "1149" @default.
- W2890857439 abstract "Primary hyperaldosteronism (PHA) is the most common form of secondary hypertension of hormonal origin. It affects about 10% of all hypertensive patients. It is connected with increased morbidity and mortality from cardiovascular diseases (CVD) compared to patients with essential hypertension of a similar age. Usually, it is an effect of bilateral adrenal hyperplasia (BAH) or aldosterone-producing adenoma (APA), more rare causes of PHA are: unilateral adrenal hyperplasia, aldosterone-producing adrenocortical carcinoma, ectopic aldosterone-producing tumors and familial hyperaldosteronism. Recent genetic studies have thrown a new light on the pathogenesis of PHA, classifying it as a channelopathy. Several mutations within the ion channels encoding genes have been identified. A possible link between primary hyperaldosteronism and polymorphism of aldosterone synthase gene and ion channel genes is still being investigated. In this manuscript, we focus on genetic aspects of primary hyperaldosteronism, and present an up-to-date compilation of available data with the widened pathogenetic approach." @default.
- W2890857439 created "2018-09-27" @default.
- W2890857439 creator A5002365088 @default.
- W2890857439 creator A5021426089 @default.
- W2890857439 creator A5033393628 @default.
- W2890857439 creator A5077686989 @default.
- W2890857439 creator A5091888669 @default.
- W2890857439 date "2018-08-31" @default.
- W2890857439 modified "2023-09-29" @default.
- W2890857439 title "Genetic aspects of primary hyperaldosteronism" @default.
- W2890857439 doi "https://doi.org/10.17219/acem/69390" @default.
- W2890857439 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29938936" @default.
- W2890857439 hasPublicationYear "2018" @default.
- W2890857439 type Work @default.
- W2890857439 sameAs 2890857439 @default.
- W2890857439 citedByCount "7" @default.
- W2890857439 countsByYear W28908574392019 @default.
- W2890857439 countsByYear W28908574392020 @default.
- W2890857439 countsByYear W28908574392021 @default.
- W2890857439 countsByYear W28908574392022 @default.
- W2890857439 countsByYear W28908574392023 @default.
- W2890857439 crossrefType "journal-article" @default.
- W2890857439 hasAuthorship W2890857439A5002365088 @default.
- W2890857439 hasAuthorship W2890857439A5021426089 @default.
- W2890857439 hasAuthorship W2890857439A5033393628 @default.
- W2890857439 hasAuthorship W2890857439A5077686989 @default.
- W2890857439 hasAuthorship W2890857439A5091888669 @default.
- W2890857439 hasBestOaLocation W28908574391 @default.
- W2890857439 hasConcept C126322002 @default.
- W2890857439 hasConcept C134018914 @default.
- W2890857439 hasConcept C198710026 @default.
- W2890857439 hasConcept C2776292634 @default.
- W2890857439 hasConcept C2777428134 @default.
- W2890857439 hasConcept C2777562237 @default.
- W2890857439 hasConcept C2777581072 @default.
- W2890857439 hasConcept C2778525890 @default.
- W2890857439 hasConcept C2780233176 @default.
- W2890857439 hasConcept C2780249997 @default.
- W2890857439 hasConcept C2781399356 @default.
- W2890857439 hasConcept C60644358 @default.
- W2890857439 hasConcept C71924100 @default.
- W2890857439 hasConcept C84393581 @default.
- W2890857439 hasConcept C86803240 @default.
- W2890857439 hasConceptScore W2890857439C126322002 @default.
- W2890857439 hasConceptScore W2890857439C134018914 @default.
- W2890857439 hasConceptScore W2890857439C198710026 @default.
- W2890857439 hasConceptScore W2890857439C2776292634 @default.
- W2890857439 hasConceptScore W2890857439C2777428134 @default.
- W2890857439 hasConceptScore W2890857439C2777562237 @default.
- W2890857439 hasConceptScore W2890857439C2777581072 @default.
- W2890857439 hasConceptScore W2890857439C2778525890 @default.
- W2890857439 hasConceptScore W2890857439C2780233176 @default.
- W2890857439 hasConceptScore W2890857439C2780249997 @default.
- W2890857439 hasConceptScore W2890857439C2781399356 @default.
- W2890857439 hasConceptScore W2890857439C60644358 @default.
- W2890857439 hasConceptScore W2890857439C71924100 @default.
- W2890857439 hasConceptScore W2890857439C84393581 @default.
- W2890857439 hasConceptScore W2890857439C86803240 @default.
- W2890857439 hasIssue "8" @default.
- W2890857439 hasLocation W28908574391 @default.
- W2890857439 hasLocation W28908574392 @default.
- W2890857439 hasOpenAccess W2890857439 @default.
- W2890857439 hasPrimaryLocation W28908574391 @default.
- W2890857439 hasRelatedWork W1145847995 @default.
- W2890857439 hasRelatedWork W1511086392 @default.
- W2890857439 hasRelatedWork W1969696852 @default.
- W2890857439 hasRelatedWork W2168778005 @default.
- W2890857439 hasRelatedWork W2430968061 @default.
- W2890857439 hasRelatedWork W2772975884 @default.
- W2890857439 hasRelatedWork W2890857439 @default.
- W2890857439 hasRelatedWork W3009578391 @default.
- W2890857439 hasRelatedWork W3135785444 @default.
- W2890857439 hasRelatedWork W4200174848 @default.
- W2890857439 hasVolume "27" @default.
- W2890857439 isParatext "false" @default.
- W2890857439 isRetracted "false" @default.
- W2890857439 magId "2890857439" @default.
- W2890857439 workType "article" @default.