Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890877748> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2890877748 endingPage "1516" @default.
- W2890877748 startingPage "1509" @default.
- W2890877748 abstract "Background Treatment targeted to achieve reduction in N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) improves outcomes in human congestive heart failure (CHF) patients. Hypothesis A pre‐specified therapeutic algorithm that increased diuretic or pimobendan usage will reduce plasma NT‐proBNP concentrations in dogs with CHF secondary to myxomatous mitral valve disease (MMVD). Animals Twenty‐six dogs with clinically stable CHF secondary to MMVD. Methods Prospective, controlled before‐and‐after study. Dogs were examined up to 3 times over 21 days. Treatment was prescribed based on NT‐proBNP as follows: <1500 pmol/L at baseline, no treatment adjustment at any point during the study (group 1); ≥1500 pmol/L and creatinine ≤3.0 mg/dL at baseline or SC visits, treatment escalated according to the algorithm (group 2); ≥1500 pmol/L at baseline, no treatment adjustment (group 3). Results N‐terminal pro‐B‐type natriuretic peptide decreased significantly in group 2 (mean change = −1736 pmol/L (95% CI, −804 to −2668), P < .001) but not in groups 1 or 3 (623 pmol/L [–631 to 1877 pmol/L], P = .14 and 685 pmol/L [–304 to 1068 pmol/L], P = .46, respectively). Serum BUN and creatinine did not change significantly between visit 0 and visit 2 in group 1 (median = 23 mg/dL [range 13‐32] versus 19 mg/dL [12‐38], P = .72 and 1.15 mg/dL [0.70‐1.40] versus 0.95 mg/dL [0.70‐1.10], P = .10, respectively) or group 2 (28 mg/dL [18‐87] versus 43.5 mg/dL [21‐160], P = .092 and 1.10 mg/dL [0.90‐2.50] versus 1.55 mg/dL [0.90‐3.30], P = .062, respectively). Conclusions and Clinical Importance Use of this treatment escalation algorithm allows effective targeting of treatment for CHF in dogs against an objective criterion." @default.
- W2890877748 created "2018-09-27" @default.
- W2890877748 creator A5048615394 @default.
- W2890877748 creator A5073582935 @default.
- W2890877748 creator A5076618455 @default.
- W2890877748 creator A5086323534 @default.
- W2890877748 date "2018-09-01" @default.
- W2890877748 modified "2023-10-01" @default.
- W2890877748 title "Effect of prespecified therapy escalation on plasma NT-proBNP concentrations in dogs with stable congestive heart failure due to myxomatous mitral valve disease" @default.
- W2890877748 cites W1986289069 @default.
- W2890877748 cites W2007276450 @default.
- W2890877748 cites W2017088015 @default.
- W2890877748 cites W2032025902 @default.
- W2890877748 cites W2048039545 @default.
- W2890877748 cites W2050473479 @default.
- W2890877748 cites W2057963038 @default.
- W2890877748 cites W2059255526 @default.
- W2890877748 cites W2065891545 @default.
- W2890877748 cites W2066228805 @default.
- W2890877748 cites W2091096727 @default.
- W2890877748 cites W2092508360 @default.
- W2890877748 cites W2117902834 @default.
- W2890877748 cites W2125184590 @default.
- W2890877748 cites W2132162955 @default.
- W2890877748 cites W2142768873 @default.
- W2890877748 cites W2171559864 @default.
- W2890877748 cites W2172005793 @default.
- W2890877748 cites W2207992373 @default.
- W2890877748 cites W22496758 @default.
- W2890877748 cites W2607896223 @default.
- W2890877748 cites W4254610672 @default.
- W2890877748 doi "https://doi.org/10.1111/jvim.15228" @default.
- W2890877748 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6189340" @default.
- W2890877748 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30216549" @default.
- W2890877748 hasPublicationYear "2018" @default.
- W2890877748 type Work @default.
- W2890877748 sameAs 2890877748 @default.
- W2890877748 citedByCount "7" @default.
- W2890877748 countsByYear W28908777482019 @default.
- W2890877748 countsByYear W28908777482020 @default.
- W2890877748 countsByYear W28908777482022 @default.
- W2890877748 countsByYear W28908777482023 @default.
- W2890877748 crossrefType "journal-article" @default.
- W2890877748 hasAuthorship W2890877748A5048615394 @default.
- W2890877748 hasAuthorship W2890877748A5073582935 @default.
- W2890877748 hasAuthorship W2890877748A5076618455 @default.
- W2890877748 hasAuthorship W2890877748A5086323534 @default.
- W2890877748 hasBestOaLocation W28908777481 @default.
- W2890877748 hasConcept C126322002 @default.
- W2890877748 hasConcept C126894567 @default.
- W2890877748 hasConcept C134018914 @default.
- W2890877748 hasConcept C164705383 @default.
- W2890877748 hasConcept C168563851 @default.
- W2890877748 hasConcept C188816634 @default.
- W2890877748 hasConcept C203092338 @default.
- W2890877748 hasConcept C2775915353 @default.
- W2890877748 hasConcept C2778198053 @default.
- W2890877748 hasConcept C2779918671 @default.
- W2890877748 hasConcept C2780074459 @default.
- W2890877748 hasConcept C2780306776 @default.
- W2890877748 hasConcept C71924100 @default.
- W2890877748 hasConceptScore W2890877748C126322002 @default.
- W2890877748 hasConceptScore W2890877748C126894567 @default.
- W2890877748 hasConceptScore W2890877748C134018914 @default.
- W2890877748 hasConceptScore W2890877748C164705383 @default.
- W2890877748 hasConceptScore W2890877748C168563851 @default.
- W2890877748 hasConceptScore W2890877748C188816634 @default.
- W2890877748 hasConceptScore W2890877748C203092338 @default.
- W2890877748 hasConceptScore W2890877748C2775915353 @default.
- W2890877748 hasConceptScore W2890877748C2778198053 @default.
- W2890877748 hasConceptScore W2890877748C2779918671 @default.
- W2890877748 hasConceptScore W2890877748C2780074459 @default.
- W2890877748 hasConceptScore W2890877748C2780306776 @default.
- W2890877748 hasConceptScore W2890877748C71924100 @default.
- W2890877748 hasIssue "5" @default.
- W2890877748 hasLocation W28908777481 @default.
- W2890877748 hasLocation W28908777482 @default.
- W2890877748 hasLocation W28908777483 @default.
- W2890877748 hasLocation W28908777484 @default.
- W2890877748 hasOpenAccess W2890877748 @default.
- W2890877748 hasPrimaryLocation W28908777481 @default.
- W2890877748 hasRelatedWork W2022141842 @default.
- W2890877748 hasRelatedWork W2043879443 @default.
- W2890877748 hasRelatedWork W2051712573 @default.
- W2890877748 hasRelatedWork W2071457715 @default.
- W2890877748 hasRelatedWork W2098870266 @default.
- W2890877748 hasRelatedWork W2106860651 @default.
- W2890877748 hasRelatedWork W2212154849 @default.
- W2890877748 hasRelatedWork W2328354663 @default.
- W2890877748 hasRelatedWork W2383671142 @default.
- W2890877748 hasRelatedWork W2385857813 @default.
- W2890877748 hasVolume "32" @default.
- W2890877748 isParatext "false" @default.
- W2890877748 isRetracted "false" @default.
- W2890877748 magId "2890877748" @default.
- W2890877748 workType "article" @default.