FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W289088742> ?p ?o ?g. }

• W289088742 abstract "The overall aim of this thesis was to explore the association between the components of the metabolic syndrome (MetS), including vitamin D, and lower urinary tract symptoms (LUTS). The focus was on the relationship between diseases of the prostate, mainly benign prostatic enlargement (BPE) and prostate cancer (PC). The study cohort consisted of 3,014 Swedish men aged 69-81 enrolled in the Swedish arm of the Osteoporotic Fractures in men (MrOs) study. The study participants were randomly selected using population registries and then contacted and asked to participate in the study. The selected men were asked to fill in questionnaires regarding a variety of items such as daily activities and physical exercise, eating-, drinkingand smoking habits, medication, past and present history of diseases, voiding habits, surgery and current treatment. They underwent investigations regarding bone mineral density, measurements of body composition such as height, weight, body mass index, body fat mass and lean mass and blood samples were obtained for analyses of a variety of variables. In a subgroup of this cohort (1,010 individuals) more extended analyses were performed. Furthermore, in a small cohort (184 individuals), the prostate gland volumes were measured through transrectal ultrasonography. Lower urinary tract symptoms were measured by the International Prostate Symptom Score and urinary incontinence (UI) was evaluated by a questionnaire. The cohort has been followed for more than 10 years. The MrOs register was coordinated with the Swedish Death Register, the Swedish Cancer Register, and the National Prostate Cancer Register. This investigation showed that LUTS and UI were neither associated with any major component of the MetS, nor associated with serum levels of vitamin D. However, serum levels of serotonin were negatively associated with LUTS and UI, while fasting glucose and adiponectin were positively associated with LUTS. Benign prostatic enlargement was associated with low levels of vitamin D, serum calcium, sex hormonebinding globulin and high-density lipoprotein cholesterol. Individuals with type 2 Diabetes mellitus (T2DM) had a decreased risk of being diagnosed with incident prostate cancer. Increased levels of vitamin D were associated with increased risk of being diagnosed with PC. Individuals with low serum c-reactive-protein levels and taller individuals had a higher risk of developing PC. Plasma levels of osteocalcin, a protein produced by osteoblasts, were lower in individuals with T2DM, and higher in individuals with incident PC. The overall conclusions in the present thesis were that vitamin D was negatively associated with BPE and positively associated with PC, however, not associated with LUTS. In addition, the end-point component of MetS, T2DM, was positively associated with BPE but inversely associated with incident PC, and finally, that osteocalcin was positively associated with incident PC." @default.
• W289088742 created "2016-06-24" @default.
• W289088742 creator A5016219725 @default.
• W289088742 date "2015-04-23" @default.
• W289088742 modified "2023-09-27" @default.
• W289088742 title "Prostate Diseases and the Metabolic Syndrome" @default.
• W289088742 cites W147193510 @default.
• W289088742 cites W1491869245 @default.
• W289088742 cites W1492633044 @default.
• W289088742 cites W1493223326 @default.
• W289088742 cites W1502255235 @default.
• W289088742 cites W1524711765 @default.
• W289088742 cites W1529465070 @default.
• W289088742 cites W1545794063 @default.
• W289088742 cites W1547745126 @default.
• W289088742 cites W1559814659 @default.
• W289088742 cites W1587875569 @default.
• W289088742 cites W1590778744 @default.
• W289088742 cites W1644798207 @default.
• W289088742 cites W1757761536 @default.
• W289088742 cites W1797123055 @default.
• W289088742 cites W1806674608 @default.
• W289088742 cites W1817709655 @default.
• W289088742 cites W1951041268 @default.
• W289088742 cites W1965068894 @default.
• W289088742 cites W1965149752 @default.
• W289088742 cites W1967026075 @default.
• W289088742 cites W1967242882 @default.
• W289088742 cites W1967638586 @default.
• W289088742 cites W1967743357 @default.
• W289088742 cites W1972110731 @default.
• W289088742 cites W1973777095 @default.
• W289088742 cites W1975135356 @default.
• W289088742 cites W1975509029 @default.
• W289088742 cites W1976713204 @default.
• W289088742 cites W1977007818 @default.
• W289088742 cites W1980740451 @default.
• W289088742 cites W1983555129 @default.
• W289088742 cites W1984764559 @default.
• W289088742 cites W1986527803 @default.
• W289088742 cites W1987264463 @default.
• W289088742 cites W1987967806 @default.
• W289088742 cites W1996787056 @default.
• W289088742 cites W1997056474 @default.
• W289088742 cites W1997978122 @default.
• W289088742 cites W1999365413 @default.
• W289088742 cites W2000737927 @default.
• W289088742 cites W2000792691 @default.
• W289088742 cites W2002930907 @default.
• W289088742 cites W2003410204 @default.
• W289088742 cites W2003473186 @default.
• W289088742 cites W2003828583 @default.
• W289088742 cites W2004483728 @default.
• W289088742 cites W2009101571 @default.
• W289088742 cites W2011336570 @default.
• W289088742 cites W2011350098 @default.
• W289088742 cites W2011725731 @default.
• W289088742 cites W2011962188 @default.
• W289088742 cites W2013339414 @default.
• W289088742 cites W2013748233 @default.
• W289088742 cites W2016392921 @default.
• W289088742 cites W2016568456 @default.
• W289088742 cites W2016582498 @default.
• W289088742 cites W2016791847 @default.
• W289088742 cites W2017596789 @default.
• W289088742 cites W2017785830 @default.
• W289088742 cites W2017975043 @default.
• W289088742 cites W2018875133 @default.
• W289088742 cites W2019258161 @default.
• W289088742 cites W2020811713 @default.
• W289088742 cites W2022505313 @default.
• W289088742 cites W2023018925 @default.
• W289088742 cites W2027467801 @default.
• W289088742 cites W2028240651 @default.
• W289088742 cites W2030405870 @default.
• W289088742 cites W2031981480 @default.
• W289088742 cites W2034512273 @default.
• W289088742 cites W2035387546 @default.
• W289088742 cites W2036577347 @default.
• W289088742 cites W2037106653 @default.
• W289088742 cites W2037997009 @default.
• W289088742 cites W2038365356 @default.
• W289088742 cites W2039234793 @default.
• W289088742 cites W2040837263 @default.
• W289088742 cites W2041080304 @default.
• W289088742 cites W2044185708 @default.
• W289088742 cites W2045504344 @default.
• W289088742 cites W2046711785 @default.
• W289088742 cites W2047030161 @default.
• W289088742 cites W2047413385 @default.
• W289088742 cites W2048763543 @default.
• W289088742 cites W2052103657 @default.
• W289088742 cites W2052268441 @default.
• W289088742 cites W2053073250 @default.
• W289088742 cites W2055374177 @default.
• W289088742 cites W2055446626 @default.
• W289088742 cites W2055648589 @default.
• W289088742 cites W2059840692 @default.
• W289088742 cites W2059851474 @default.
• W289088742 cites W2061579222 @default.

• next