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- W2890894233 abstract "To summarize the literature on the long-term impact of perioperative opioids in colorectal cancer.Combined results from two searching strategies in PubMed/MEDLINE (1950-2018), based on a PICO approach; P: Opioid influence on cancer-related long-term outcome in patient undergoing colorectal surgery; I: Opioid drugs administered in the perioperative period; C: Correlation between dose and/or type of opioid with long-term oncologic outcome; O: Disease-free survival and/or overall survival (OS).Thirteen articles fulfilled the predetermined inclusion criteria. Due to the heterogeneity of the different studies, a quantitative meta-analysis to sum the evidence was deemed unfeasible.Our review indicates that there is no conclusive evidence to avoid the use of opioids with the goal of reducing the risk of recurrence in colorectal cancer." @default.
- W2890894233 created "2018-09-27" @default.
- W2890894233 creator A5025645999 @default.
- W2890894233 creator A5040655193 @default.
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- W2890894233 date "2018-09-01" @default.
- W2890894233 modified "2023-10-13" @default.
- W2890894233 title "Perioperative opioids and colorectal cancer recurrence: a systematic review of the literature" @default.
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- W2890894233 doi "https://doi.org/10.2217/pmt-2018-0029" @default.
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