FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890901068> ?p ?o ?g. }

• W2890901068 abstract "Abstract The phytohormone 7- iso -(+)-jasmonoyl- L -isoleucine (JA-Ile) mediates plant defense responses against herbivore and pathogen attack, and thus increases plant resistance against foreign invaders. However, JA-Ile also causes growth inhibition; and therefore JA-Ile is not a practical chemical regulator of plant defense responses. Here, we describe the rational design and synthesis of a small molecule agonist that can upregulate defense-related gene expression and promote pathogen resistance at concentrations that do not cause growth inhibition in Arabidopsis . By stabilizing interactions between COI1 and JAZ9 and JAZ10 but no other JAZ isoforms, the agonist leads to formation of JA-Ile co-receptors that selectively activate the JAZ9-EIN3/EIL1-ORA59 signaling pathway. The design of a JA-Ile agonist with high selectivity for specific protein subtypes may help promote the development of chemical regulators that do not cause a tradeoff between growth and defense." @default.
• W2890901068 created "2018-09-27" @default.
• W2890901068 creator A5008268308 @default.
• W2890901068 creator A5014694345 @default.
• W2890901068 creator A5017695005 @default.
• W2890901068 creator A5039019898 @default.
• W2890901068 creator A5040534546 @default.
• W2890901068 creator A5040781400 @default.
• W2890901068 creator A5067197714 @default.
• W2890901068 creator A5076974173 @default.
• W2890901068 creator A5077925546 @default.
• W2890901068 creator A5083204253 @default.
• W2890901068 creator A5086202322 @default.
• W2890901068 creator A5088237819 @default.
• W2890901068 date "2018-09-07" @default.
• W2890901068 modified "2023-10-17" @default.
• W2890901068 title "A rationally designed JAZ subtype-selective agonist of jasmonate perception" @default.
• W2890901068 cites W1930097109 @default.
• W2890901068 cites W1932590484 @default.
• W2890901068 cites W1964548187 @default.
• W2890901068 cites W1964741545 @default.
• W2890901068 cites W1964814071 @default.
• W2890901068 cites W1965917470 @default.
• W2890901068 cites W1971251199 @default.
• W2890901068 cites W1972444108 @default.
• W2890901068 cites W1975920666 @default.
• W2890901068 cites W1976499671 @default.
• W2890901068 cites W1977968790 @default.
• W2890901068 cites W1981546231 @default.
• W2890901068 cites W1985774720 @default.
• W2890901068 cites W1986662234 @default.
• W2890901068 cites W1991773625 @default.
• W2890901068 cites W1991794210 @default.
• W2890901068 cites W2003439504 @default.
• W2890901068 cites W2005906963 @default.
• W2890901068 cites W2011929061 @default.
• W2890901068 cites W2019318459 @default.
• W2890901068 cites W2023481684 @default.
• W2890901068 cites W2029058641 @default.
• W2890901068 cites W2032156607 @default.
• W2890901068 cites W2039256908 @default.
• W2890901068 cites W2042758661 @default.
• W2890901068 cites W2043676058 @default.
• W2890901068 cites W2043989922 @default.
• W2890901068 cites W2048291392 @default.
• W2890901068 cites W2050018481 @default.
• W2890901068 cites W2052498510 @default.
• W2890901068 cites W2061937485 @default.
• W2890901068 cites W2067174909 @default.
• W2890901068 cites W2069123478 @default.
• W2890901068 cites W2076913878 @default.
• W2890901068 cites W2080705428 @default.
• W2890901068 cites W2080805933 @default.
• W2890901068 cites W2081693079 @default.
• W2890901068 cites W2083159944 @default.
• W2890901068 cites W2084720613 @default.
• W2890901068 cites W2085512599 @default.
• W2890901068 cites W2086360829 @default.
• W2890901068 cites W2089105877 @default.
• W2890901068 cites W2092726795 @default.
• W2890901068 cites W2094477559 @default.
• W2890901068 cites W2096751405 @default.
• W2890901068 cites W2099616027 @default.
• W2890901068 cites W2099701147 @default.
• W2890901068 cites W2108418392 @default.
• W2890901068 cites W2108527506 @default.
• W2890901068 cites W2114425137 @default.
• W2890901068 cites W2114973337 @default.
• W2890901068 cites W2117234604 @default.
• W2890901068 cites W2123019342 @default.
• W2890901068 cites W2123995489 @default.
• W2890901068 cites W2139714472 @default.
• W2890901068 cites W2146151986 @default.
• W2890901068 cites W2146577134 @default.
• W2890901068 cites W2147993766 @default.
• W2890901068 cites W2149993527 @default.
• W2890901068 cites W2156475745 @default.
• W2890901068 cites W2157278055 @default.
• W2890901068 cites W2160164225 @default.
• W2890901068 cites W2161512142 @default.
• W2890901068 cites W2165924949 @default.
• W2890901068 cites W2171788269 @default.
• W2890901068 cites W2266923894 @default.
• W2890901068 cites W2278902825 @default.
• W2890901068 cites W2327762678 @default.
• W2890901068 cites W2408483783 @default.
• W2890901068 cites W2479389577 @default.
• W2890901068 cites W2508579932 @default.
• W2890901068 cites W2561467170 @default.
• W2890901068 cites W2569926645 @default.
• W2890901068 cites W2592806978 @default.
• W2890901068 cites W2655022311 @default.
• W2890901068 cites W2782456208 @default.
• W2890901068 doi "https://doi.org/10.1038/s41467-018-06135-y" @default.
• W2890901068 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6128907" @default.
• W2890901068 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30194307" @default.
• W2890901068 hasPublicationYear "2018" @default.
• W2890901068 type Work @default.
• W2890901068 sameAs 2890901068 @default.
• W2890901068 citedByCount "42" @default.

• next