Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890911580> ?p ?o ?g. }
- W2890911580 abstract "Abstract Chemical signaling underlies both temporally phasic and extended activity in the brain. Phasic activity can be monitored by implanted sensors, but chronic recording of such chemical signals has been difficult because the capacity to measure them degrades over time. This degradation has been attributed to tissue damage progressively produced by the sensors and failure of the sensors themselves. We report methods that surmount these problems through the development of sensors having diameters as small as individual neuronal cell bodies (<10 µm). These micro-invasive probes (µIPs) markedly reduced expression of detectable markers of inflammation and tissue damage in a rodent test model. The chronically implanted µIPs provided stable operation in monitoring sub-second fluctuations in stimulation-evoked dopamine in anesthetized rats for over a year. These findings demonstrate that monitoring of chemical activity patterns in the brain over at least year-long periods, long a goal of both basic and clinical neuroscience, is achievable." @default.
- W2890911580 created "2018-09-27" @default.
- W2890911580 creator A5027381296 @default.
- W2890911580 creator A5035254479 @default.
- W2890911580 creator A5042597057 @default.
- W2890911580 creator A5061683153 @default.
- W2890911580 creator A5069814354 @default.
- W2890911580 creator A5076922348 @default.
- W2890911580 creator A5077671596 @default.
- W2890911580 creator A5081686751 @default.
- W2890911580 creator A5081776349 @default.
- W2890911580 creator A5088182347 @default.
- W2890911580 date "2018-09-12" @default.
- W2890911580 modified "2023-10-11" @default.
- W2890911580 title "Cellular-scale probes enable stable chronic subsecond monitoring of dopamine neurochemicals in a rodent model" @default.
- W2890911580 cites W1590155876 @default.
- W2890911580 cites W1806810949 @default.
- W2890911580 cites W1951642440 @default.
- W2890911580 cites W1974898145 @default.
- W2890911580 cites W1975525458 @default.
- W2890911580 cites W1975669290 @default.
- W2890911580 cites W1978902739 @default.
- W2890911580 cites W1980144398 @default.
- W2890911580 cites W1982976081 @default.
- W2890911580 cites W1985061395 @default.
- W2890911580 cites W1996542318 @default.
- W2890911580 cites W1999169980 @default.
- W2890911580 cites W2000934372 @default.
- W2890911580 cites W2001477745 @default.
- W2890911580 cites W2008537745 @default.
- W2890911580 cites W2009967907 @default.
- W2890911580 cites W2014971298 @default.
- W2890911580 cites W2028103147 @default.
- W2890911580 cites W2033922262 @default.
- W2890911580 cites W2045060416 @default.
- W2890911580 cites W2045747400 @default.
- W2890911580 cites W2049072600 @default.
- W2890911580 cites W2049459393 @default.
- W2890911580 cites W2055432244 @default.
- W2890911580 cites W2061680435 @default.
- W2890911580 cites W2067692467 @default.
- W2890911580 cites W2069978126 @default.
- W2890911580 cites W2071050716 @default.
- W2890911580 cites W2071748149 @default.
- W2890911580 cites W2079869150 @default.
- W2890911580 cites W2090157379 @default.
- W2890911580 cites W2091634484 @default.
- W2890911580 cites W2120340503 @default.
- W2890911580 cites W2132182674 @default.
- W2890911580 cites W2144976153 @default.
- W2890911580 cites W2147538742 @default.
- W2890911580 cites W2149589531 @default.
- W2890911580 cites W2340994737 @default.
- W2890911580 cites W2586628367 @default.
- W2890911580 cites W2588055353 @default.
- W2890911580 cites W2588766868 @default.
- W2890911580 cites W2612079677 @default.
- W2890911580 cites W2768248760 @default.
- W2890911580 doi "https://doi.org/10.1038/s42003-018-0147-y" @default.
- W2890911580 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6135761" @default.
- W2890911580 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30272020" @default.
- W2890911580 hasPublicationYear "2018" @default.
- W2890911580 type Work @default.
- W2890911580 sameAs 2890911580 @default.
- W2890911580 citedByCount "49" @default.
- W2890911580 countsByYear W28909115802019 @default.
- W2890911580 countsByYear W28909115802020 @default.
- W2890911580 countsByYear W28909115802021 @default.
- W2890911580 countsByYear W28909115802022 @default.
- W2890911580 countsByYear W28909115802023 @default.
- W2890911580 crossrefType "journal-article" @default.
- W2890911580 hasAuthorship W2890911580A5027381296 @default.
- W2890911580 hasAuthorship W2890911580A5035254479 @default.
- W2890911580 hasAuthorship W2890911580A5042597057 @default.
- W2890911580 hasAuthorship W2890911580A5061683153 @default.
- W2890911580 hasAuthorship W2890911580A5069814354 @default.
- W2890911580 hasAuthorship W2890911580A5076922348 @default.
- W2890911580 hasAuthorship W2890911580A5077671596 @default.
- W2890911580 hasAuthorship W2890911580A5081686751 @default.
- W2890911580 hasAuthorship W2890911580A5081776349 @default.
- W2890911580 hasAuthorship W2890911580A5088182347 @default.
- W2890911580 hasBestOaLocation W28909115801 @default.
- W2890911580 hasConcept C126322002 @default.
- W2890911580 hasConcept C136229726 @default.
- W2890911580 hasConcept C169760540 @default.
- W2890911580 hasConcept C185592680 @default.
- W2890911580 hasConcept C18903297 @default.
- W2890911580 hasConcept C24998067 @default.
- W2890911580 hasConcept C2776914184 @default.
- W2890911580 hasConcept C2778914748 @default.
- W2890911580 hasConcept C513476851 @default.
- W2890911580 hasConcept C71924100 @default.
- W2890911580 hasConcept C86803240 @default.
- W2890911580 hasConceptScore W2890911580C126322002 @default.
- W2890911580 hasConceptScore W2890911580C136229726 @default.
- W2890911580 hasConceptScore W2890911580C169760540 @default.
- W2890911580 hasConceptScore W2890911580C185592680 @default.
- W2890911580 hasConceptScore W2890911580C18903297 @default.
- W2890911580 hasConceptScore W2890911580C24998067 @default.
- W2890911580 hasConceptScore W2890911580C2776914184 @default.