FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890926929> ?p ?o ?g. }

• W2890926929 endingPage "232" @default.
• W2890926929 startingPage "225" @default.
• W2890926929 abstract "Neuronal Lamin regulates motor circuit integrity and controls motor function and lifespan – Neuronal aging involves a progressive decline in cognitive abilities and loss of motor function. Mutations in human Lamin genes (LMNA, LMNB1, LMNB2) lead to a wide-range of diseases including muscular dystrophy, peripheral neuropathy and progeria. Here we investigate the role of neuronal Lamin in regulating age-related phenotypes. Neuronal targeting of Lamin led to shortened lifespan, progressive impairment of motor function and loss of dopaminergic (DA) neurons within the protocerebral anterior medial (PAM) cluster in the Drosophila melanogaster brain. Loss of neuronal Lamin caused an age-related decline in neural physiology, with slower neurotransmission and increased chance of motor circuit failure with age. Unexpectedly, Lamin-dependent decline in motor function was specific for the chemical synapses of the dorsal longitudinal muscle (DLM). Together (...)" @default.
• W2890926929 created "2018-09-27" @default.
• W2890926929 creator A5003486623 @default.
• W2890926929 creator A5007177310 @default.
• W2890926929 creator A5008566365 @default.
• W2890926929 creator A5021125407 @default.
• W2890926929 creator A5039567720 @default.
• W2890926929 creator A5048622739 @default.
• W2890926929 date "2018-09-10" @default.
• W2890926929 modified "2023-10-17" @default.
• W2890926929 title "Neuronal Lamin regulates motor circuit integrity and controls motor function and lifespan" @default.
• W2890926929 cites W1966282260 @default.
• W2890926929 cites W1976316003 @default.
• W2890926929 cites W1978257498 @default.
• W2890926929 cites W1998211637 @default.
• W2890926929 cites W2003592355 @default.
• W2890926929 cites W2005508231 @default.
• W2890926929 cites W2005833274 @default.
• W2890926929 cites W2008830477 @default.
• W2890926929 cites W2022954501 @default.
• W2890926929 cites W2030395075 @default.
• W2890926929 cites W2035989121 @default.
• W2890926929 cites W2051898968 @default.
• W2890926929 cites W2058666198 @default.
• W2890926929 cites W2065776621 @default.
• W2890926929 cites W2066501944 @default.
• W2890926929 cites W2070989134 @default.
• W2890926929 cites W2072810104 @default.
• W2890926929 cites W2074344918 @default.
• W2890926929 cites W2076445219 @default.
• W2890926929 cites W2082600456 @default.
• W2890926929 cites W2082815622 @default.
• W2890926929 cites W2114526838 @default.
• W2890926929 cites W2126525177 @default.
• W2890926929 cites W2134468905 @default.
• W2890926929 cites W2136406126 @default.
• W2890926929 cites W2136640493 @default.
• W2890926929 cites W2150972545 @default.
• W2890926929 cites W2157844171 @default.
• W2890926929 cites W2168743086 @default.
• W2890926929 cites W2203120038 @default.
• W2890926929 cites W2315940699 @default.
• W2890926929 cites W2418359239 @default.
• W2890926929 cites W2574518682 @default.
• W2890926929 cites W2592675809 @default.
• W2890926929 cites W4254063814 @default.
• W2890926929 doi "https://doi.org/10.15698/cst2018.09.152" @default.
• W2890926929 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6558924" @default.
• W2890926929 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31225490" @default.
• W2890926929 hasPublicationYear "2018" @default.
• W2890926929 type Work @default.
• W2890926929 sameAs 2890926929 @default.
• W2890926929 citedByCount "12" @default.
• W2890926929 countsByYear W28909269292019 @default.
• W2890926929 countsByYear W28909269292021 @default.
• W2890926929 countsByYear W28909269292022 @default.
• W2890926929 countsByYear W28909269292023 @default.
• W2890926929 crossrefType "journal-article" @default.
• W2890926929 hasAuthorship W2890926929A5003486623 @default.
• W2890926929 hasAuthorship W2890926929A5007177310 @default.
• W2890926929 hasAuthorship W2890926929A5008566365 @default.
• W2890926929 hasAuthorship W2890926929A5021125407 @default.
• W2890926929 hasAuthorship W2890926929A5039567720 @default.
• W2890926929 hasAuthorship W2890926929A5048622739 @default.
• W2890926929 hasBestOaLocation W28909269291 @default.
• W2890926929 hasConcept C104317684 @default.
• W2890926929 hasConcept C169760540 @default.
• W2890926929 hasConcept C179093185 @default.
• W2890926929 hasConcept C2776752467 @default.
• W2890926929 hasConcept C2778465436 @default.
• W2890926929 hasConcept C2780654407 @default.
• W2890926929 hasConcept C2780723820 @default.
• W2890926929 hasConcept C2780775167 @default.
• W2890926929 hasConcept C54355233 @default.
• W2890926929 hasConcept C86803240 @default.
• W2890926929 hasConceptScore W2890926929C104317684 @default.
• W2890926929 hasConceptScore W2890926929C169760540 @default.
• W2890926929 hasConceptScore W2890926929C179093185 @default.
• W2890926929 hasConceptScore W2890926929C2776752467 @default.
• W2890926929 hasConceptScore W2890926929C2778465436 @default.
• W2890926929 hasConceptScore W2890926929C2780654407 @default.
• W2890926929 hasConceptScore W2890926929C2780723820 @default.
• W2890926929 hasConceptScore W2890926929C2780775167 @default.
• W2890926929 hasConceptScore W2890926929C54355233 @default.
• W2890926929 hasConceptScore W2890926929C86803240 @default.
• W2890926929 hasIssue "9" @default.
• W2890926929 hasLocation W28909269291 @default.
• W2890926929 hasLocation W28909269292 @default.
• W2890926929 hasLocation W28909269293 @default.
• W2890926929 hasLocation W28909269294 @default.
• W2890926929 hasLocation W28909269295 @default.
• W2890926929 hasOpenAccess W2890926929 @default.
• W2890926929 hasPrimaryLocation W28909269291 @default.
• W2890926929 hasRelatedWork W1976506286 @default.
• W2890926929 hasRelatedWork W1979404244 @default.
• W2890926929 hasRelatedWork W2066816830 @default.
• W2890926929 hasRelatedWork W2088983871 @default.
• W2890926929 hasRelatedWork W2152880265 @default.

• next