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- W2890932659 endingPage "188" @default.
- W2890932659 startingPage "166" @default.
- W2890932659 abstract "Breast implant-associated anaplastic large cell lymphoma is a newly recognized provisional entity in the 2017 revision of the World Health Organization Classification of Tumors of Hematopoietic and Lymphoid Tissues. It is an uncommon, slow growing T-cell lymphoma with morphology and immunophenotype similar to anaplastic lymphoma kinase-negative anaplastic large cell lymphoma. However, the presentation and treatment are unique. Breast implant-associated anaplastic large cell lymphoma often presents as a unilateral effusion confined to the capsule of a textured-surface breast implant, a median time of 9 years after the initial implants have been placed. Although it follows an indolent clinical course, breast implant-associated anaplastic large cell lymphoma has the potential to form a mass, to invade locally through the capsule into breast parenchyma or soft tissue and/or to spread to regional lymph nodes. In most cases, an explantation with a complete capsulectomy removing all disease, without chemotherapy is considered to be curative and confers an excellent event free and overall survival. Here we provide a comprehensive review of breast implant-associated anaplastic large cell lymphoma, including history, epidemiology, clinical features, imaging and pathology findings, pathologic handling, pathogenic mechanisms, model for progression, therapy and outcomes as well as an analysis of causality between breast implants and anaplastic large cell lymphoma." @default.
- W2890932659 created "2018-09-27" @default.
- W2890932659 creator A5000027373 @default.
- W2890932659 creator A5000980110 @default.
- W2890932659 creator A5035449851 @default.
- W2890932659 creator A5044226126 @default.
- W2890932659 creator A5046483439 @default.
- W2890932659 creator A5091887796 @default.
- W2890932659 date "2019-02-01" @default.
- W2890932659 modified "2023-10-16" @default.
- W2890932659 title "Breast implant-associated anaplastic large cell lymphoma: a review" @default.
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