FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890935742> ?p ?o ?g. }

• W2890935742 endingPage "581" @default.
• W2890935742 startingPage "571" @default.
• W2890935742 abstract "Purpose The purpose of this study was to report on a 10-year assessment after the application of recombinant human bone morphogenetic protein 7 (rhBMP-7) for the reconstruction of alveolar clefts. Patients and Methods This study was conducted as a prospective phase II clinical trial on 9 unilateral and 2 bilateral alveolar clefts that received rhBMP-7 (Osigraft; Stryker Biotech, UK). The mean age of the patients at surgery was 10.4 years. At 6 months postoperatively, occlusal radiographs were taken to evaluate bone formation at the cleft site. Patients were followed within the routine cleft care pathway for 10 years to monitor the impact of bone morphogenetic protein 7 on orthodontic treatments and maxillary growth. Radiographs were taken according to the standard cleft care protocol. Results The radiographic assessment of the unilateral cleft lip and palate cases suggested good bone formation with a Kindelan score of grade 1 or 2. The bilateral alveolar cleft cases had a score of grade 3 or 4, indicating failure or partial failure. The children with successful grafts underwent a routine orthodontic follow-up without incident. The maxillary growth appeared to be similar to that in cases grafted with autogenous bone. No long-term complications and no abnormal pattern of bone formation were detected. Conclusions The study provides unique evidence on the long-term safety of rhBMP-7 when applied at the area of skeletal immaturity for the reconstruction of alveolar clefts in children. The purpose of this study was to report on a 10-year assessment after the application of recombinant human bone morphogenetic protein 7 (rhBMP-7) for the reconstruction of alveolar clefts. This study was conducted as a prospective phase II clinical trial on 9 unilateral and 2 bilateral alveolar clefts that received rhBMP-7 (Osigraft; Stryker Biotech, UK). The mean age of the patients at surgery was 10.4 years. At 6 months postoperatively, occlusal radiographs were taken to evaluate bone formation at the cleft site. Patients were followed within the routine cleft care pathway for 10 years to monitor the impact of bone morphogenetic protein 7 on orthodontic treatments and maxillary growth. Radiographs were taken according to the standard cleft care protocol. The radiographic assessment of the unilateral cleft lip and palate cases suggested good bone formation with a Kindelan score of grade 1 or 2. The bilateral alveolar cleft cases had a score of grade 3 or 4, indicating failure or partial failure. The children with successful grafts underwent a routine orthodontic follow-up without incident. The maxillary growth appeared to be similar to that in cases grafted with autogenous bone. No long-term complications and no abnormal pattern of bone formation were detected. The study provides unique evidence on the long-term safety of rhBMP-7 when applied at the area of skeletal immaturity for the reconstruction of alveolar clefts in children." @default.
• W2890935742 created "2018-09-27" @default.
• W2890935742 creator A5024120490 @default.
• W2890935742 creator A5025522999 @default.
• W2890935742 date "2019-03-01" @default.
• W2890935742 modified "2023-09-25" @default.
• W2890935742 title "The Clinical Application of Recombinant Human Bone Morphogenetic Protein 7 for Reconstruction of Alveolar Cleft: 10 Years' Follow-Up" @default.
• W2890935742 cites W1535047284 @default.
• W2890935742 cites W1912814873 @default.
• W2890935742 cites W1965875788 @default.
• W2890935742 cites W1972539912 @default.
• W2890935742 cites W1975322656 @default.
• W2890935742 cites W1979942903 @default.
• W2890935742 cites W1996670793 @default.
• W2890935742 cites W2003454650 @default.
• W2890935742 cites W2011490281 @default.
• W2890935742 cites W2027116665 @default.
• W2890935742 cites W2028050465 @default.
• W2890935742 cites W2031954741 @default.
• W2890935742 cites W2036734184 @default.
• W2890935742 cites W2044977777 @default.
• W2890935742 cites W2064864666 @default.
• W2890935742 cites W2068174938 @default.
• W2890935742 cites W2072929879 @default.
• W2890935742 cites W2074645659 @default.
• W2890935742 cites W2088408891 @default.
• W2890935742 cites W2121685615 @default.
• W2890935742 cites W2139457077 @default.
• W2890935742 cites W2143793104 @default.
• W2890935742 cites W2145962233 @default.
• W2890935742 cites W2161004170 @default.
• W2890935742 cites W2178205997 @default.
• W2890935742 cites W2329311838 @default.
• W2890935742 cites W2555287445 @default.
• W2890935742 cites W2620931422 @default.
• W2890935742 cites W4255781844 @default.
• W2890935742 doi "https://doi.org/10.1016/j.joms.2018.08.031" @default.
• W2890935742 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30273547" @default.
• W2890935742 hasPublicationYear "2019" @default.
• W2890935742 type Work @default.
• W2890935742 sameAs 2890935742 @default.
• W2890935742 citedByCount "8" @default.
• W2890935742 countsByYear W28909357422019 @default.
• W2890935742 countsByYear W28909357422021 @default.
• W2890935742 countsByYear W28909357422022 @default.
• W2890935742 countsByYear W28909357422023 @default.
• W2890935742 crossrefType "journal-article" @default.
• W2890935742 hasAuthorship W2890935742A5024120490 @default.
• W2890935742 hasAuthorship W2890935742A5025522999 @default.
• W2890935742 hasBestOaLocation W28909357422 @default.
• W2890935742 hasConcept C104317684 @default.
• W2890935742 hasConcept C141071460 @default.
• W2890935742 hasConcept C151279780 @default.
• W2890935742 hasConcept C185592680 @default.
• W2890935742 hasConcept C199343813 @default.
• W2890935742 hasConcept C31507581 @default.
• W2890935742 hasConcept C36454342 @default.
• W2890935742 hasConcept C55493867 @default.
• W2890935742 hasConcept C71924100 @default.
• W2890935742 hasConceptScore W2890935742C104317684 @default.
• W2890935742 hasConceptScore W2890935742C141071460 @default.
• W2890935742 hasConceptScore W2890935742C151279780 @default.
• W2890935742 hasConceptScore W2890935742C185592680 @default.
• W2890935742 hasConceptScore W2890935742C199343813 @default.
• W2890935742 hasConceptScore W2890935742C31507581 @default.
• W2890935742 hasConceptScore W2890935742C36454342 @default.
• W2890935742 hasConceptScore W2890935742C55493867 @default.
• W2890935742 hasConceptScore W2890935742C71924100 @default.
• W2890935742 hasIssue "3" @default.
• W2890935742 hasLocation W28909357421 @default.
• W2890935742 hasLocation W28909357422 @default.
• W2890935742 hasLocation W28909357423 @default.
• W2890935742 hasOpenAccess W2890935742 @default.
• W2890935742 hasPrimaryLocation W28909357421 @default.
• W2890935742 hasRelatedWork W1578936140 @default.
• W2890935742 hasRelatedWork W2041688999 @default.
• W2890935742 hasRelatedWork W2095660657 @default.
• W2890935742 hasRelatedWork W2110911000 @default.
• W2890935742 hasRelatedWork W2153657212 @default.
• W2890935742 hasRelatedWork W2265509125 @default.
• W2890935742 hasRelatedWork W2406353353 @default.
• W2890935742 hasRelatedWork W2435963117 @default.
• W2890935742 hasRelatedWork W3077413350 @default.
• W2890935742 hasRelatedWork W4244562344 @default.
• W2890935742 hasVolume "77" @default.
• W2890935742 isParatext "false" @default.
• W2890935742 isRetracted "false" @default.
• W2890935742 magId "2890935742" @default.
• W2890935742 workType "article" @default.