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- W2890943307 abstract "BACKGROUND:Stroke caused by intracerebral haemorrhage (ICH) has high mortality rate. Among various risk factors for ICH, hypertension is the most important factor. Certain population studies have reported a paradox of inverse association between serum cholesterol and risk of ICH. This study is to look for correlation between lipid profile and ICH.AIMS AND OBJECTIVES:The study is designed to evaluate the serum lipid profile total cholesterol (TC), triglycerides (TGL), high density cholesterol (HDL-C), very low density cholesterol (VLDL-C) and low density cholesterol (LDL-C) in intracerebral haemorrhage patients and look for correlation.METHODOLOGY:50 patients with ICH admitted in Thanjavur Medical College Hospital, Thanjavur who fulfilled the inclusion and exclusion criteria were selected. It is a hospital based observational study. History, clinical examination and investigations (CT & MRI Brain and basic blood biochemistry with serum lipid profile) were collected and the data were analysed statistically.RESULTS:Majority of the ICH patients in our study were > 55 years and were males. Basal ganglia was the commonest site and hypertension was the important risk factor. The total serum cholesterol was < 200mg/dl in 72 % of our patients, with a mean of 168.09 ±43.74mg%. Serum triglyceride level was <150 mg/dl in 74%, with a mean of 124.12 ±50.76mg%. LDL-cholesterol was <130mg /dl in 68 % of patients, with mean of 108.26±43.31mg%. HDL-C was < 40 mg/dl in 76% of patients and VLDL-C was < 30mg/dl in 72% patients. The various lipid fractions observed were found to be low in majority of our ICH patients (p value < 0.05), suggesting a negative association between the two. The results obtained were comparable to other similar studies.CONCLUSION:Majority of intracerebral haemorrhage patients in our study had lower levels of total cholesterol, triglyceride, HDL-C, LDL-C and VLDL-C. Whether the inverse association between serum lipid levels and ICH is a true causal association or only by chance due to other common confounding factors needs to be evaluated with large scale studies." @default.
- W2890943307 created "2018-09-27" @default.
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- W2890943307 date "2015-04-01" @default.
- W2890943307 modified "2023-09-27" @default.
- W2890943307 title "Study of Lipid Profile in Intracerebral Haemorrhage" @default.
- W2890943307 hasPublicationYear "2015" @default.
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