Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890958102> ?p ?o ?g. }
- W2890958102 abstract "Focal adhesions (FAs) and adherens junctions (AJs), which serve as a mechanical interface of cell-matrix and cell-cell interactions, respectively, experience tensile force either originating from the deformation of the surrounding tissues or generated by the actomyosin machinery in the cell. These mechanical inputs cause enlargement of FAs and AJs, while the detailed mechanism for the force-dependent development of FAs and AJs remain unclear. Both FAs and AJs provide sites for tethering of actin filaments and actin polymerization. Here, we develop a cell-free system, in which actin filaments are tethered to glass surfaces, and show that application of tensile force to the tethered filaments in the cell extract induces accumulation of several FA and AJ proteins, associated with further accumulation of actin filaments via de novo actin polymerization. Decline in the tensile force results in a decrease in the amount of the accumulated proteins. These results suggest that the tensile force acting on the tethered actin filaments plays a crucial role in the accumulation of FA and AJ proteins." @default.
- W2890958102 created "2018-09-27" @default.
- W2890958102 creator A5050648960 @default.
- W2890958102 creator A5054722414 @default.
- W2890958102 creator A5064068441 @default.
- W2890958102 creator A5089520394 @default.
- W2890958102 date "2018-09-11" @default.
- W2890958102 modified "2023-09-23" @default.
- W2890958102 title "Tensile Loads on Tethered Actin Filaments Induce Accumulation of Cell Adhesion-Associated Proteins in Vitro" @default.
- W2890958102 cites W137372458 @default.
- W2890958102 cites W1590619267 @default.
- W2890958102 cites W1840209374 @default.
- W2890958102 cites W1970970501 @default.
- W2890958102 cites W1982957540 @default.
- W2890958102 cites W1983987567 @default.
- W2890958102 cites W1984653721 @default.
- W2890958102 cites W1988194926 @default.
- W2890958102 cites W1989061606 @default.
- W2890958102 cites W1992499848 @default.
- W2890958102 cites W1994843364 @default.
- W2890958102 cites W2002577396 @default.
- W2890958102 cites W2004208717 @default.
- W2890958102 cites W2006338705 @default.
- W2890958102 cites W2006568580 @default.
- W2890958102 cites W2007554905 @default.
- W2890958102 cites W2011645599 @default.
- W2890958102 cites W2022806583 @default.
- W2890958102 cites W2025071422 @default.
- W2890958102 cites W2038976026 @default.
- W2890958102 cites W2044939023 @default.
- W2890958102 cites W2055601386 @default.
- W2890958102 cites W2056229955 @default.
- W2890958102 cites W2062904571 @default.
- W2890958102 cites W2068092779 @default.
- W2890958102 cites W2073177357 @default.
- W2890958102 cites W2074213768 @default.
- W2890958102 cites W2081438791 @default.
- W2890958102 cites W2086603807 @default.
- W2890958102 cites W2091119718 @default.
- W2890958102 cites W2098159442 @default.
- W2890958102 cites W2107129976 @default.
- W2890958102 cites W2108162507 @default.
- W2890958102 cites W2111683138 @default.
- W2890958102 cites W2114469101 @default.
- W2890958102 cites W2116527577 @default.
- W2890958102 cites W2119222110 @default.
- W2890958102 cites W2119632652 @default.
- W2890958102 cites W2122247339 @default.
- W2890958102 cites W2125644189 @default.
- W2890958102 cites W2127789189 @default.
- W2890958102 cites W2128797396 @default.
- W2890958102 cites W2132375258 @default.
- W2890958102 cites W2138168533 @default.
- W2890958102 cites W2139731224 @default.
- W2890958102 cites W2141075109 @default.
- W2890958102 cites W2146544270 @default.
- W2890958102 cites W2147857868 @default.
- W2890958102 cites W2149873896 @default.
- W2890958102 cites W2150214660 @default.
- W2890958102 cites W2153626442 @default.
- W2890958102 cites W2160352413 @default.
- W2890958102 cites W2166529760 @default.
- W2890958102 cites W2168012657 @default.
- W2890958102 cites W2172039086 @default.
- W2890958102 cites W2443492442 @default.
- W2890958102 cites W2563098669 @default.
- W2890958102 cites W2606654239 @default.
- W2890958102 cites W2731121207 @default.
- W2890958102 cites W2169296807 @default.
- W2890958102 doi "https://doi.org/10.1021/acs.langmuir.8b02076" @default.
- W2890958102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30204447" @default.
- W2890958102 hasPublicationYear "2018" @default.
- W2890958102 type Work @default.
- W2890958102 sameAs 2890958102 @default.
- W2890958102 citedByCount "2" @default.
- W2890958102 countsByYear W28909581022019 @default.
- W2890958102 countsByYear W28909581022021 @default.
- W2890958102 crossrefType "journal-article" @default.
- W2890958102 hasAuthorship W2890958102A5050648960 @default.
- W2890958102 hasAuthorship W2890958102A5054722414 @default.
- W2890958102 hasAuthorship W2890958102A5064068441 @default.
- W2890958102 hasAuthorship W2890958102A5089520394 @default.
- W2890958102 hasConcept C112950240 @default.
- W2890958102 hasConcept C12554922 @default.
- W2890958102 hasConcept C125705527 @default.
- W2890958102 hasConcept C14228908 @default.
- W2890958102 hasConcept C142669718 @default.
- W2890958102 hasConcept C1491633281 @default.
- W2890958102 hasConcept C149402561 @default.
- W2890958102 hasConcept C151166631 @default.
- W2890958102 hasConcept C159985019 @default.
- W2890958102 hasConcept C178790620 @default.
- W2890958102 hasConcept C185592680 @default.
- W2890958102 hasConcept C189040839 @default.
- W2890958102 hasConcept C189165786 @default.
- W2890958102 hasConcept C192562407 @default.
- W2890958102 hasConcept C201508349 @default.
- W2890958102 hasConcept C2993400109 @default.
- W2890958102 hasConcept C3620293 @default.
- W2890958102 hasConcept C55493867 @default.