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• W2890960891 abstract "The global signal of resting-state functional magnetic resonance imaging (fMRI) constitutes an intrinsic fluctuation and presents an opportunity to characterize and understand the activity of the whole brain. Recently, evidence that the global signal contains neurophysiologic information has been growing, but the global signal of electroencephalography (EEG) has never been determined.We developed a new method to obtain the EEG global signal. The EEG global signal was reconstructed by the reference electrode standardization technique and represented the outer cortical electrophysiological activity. To investigate its relationship with the global signal of resting-state fMRI, a simultaneous EEG-fMRI signal was recorded, and this was analyzed in 24 subjects.We found that the global signal of resting-state fMRI showed a positive correlation with power fluctuations of the EEG global signal in the γ band (30-45 Hz) and a negative correlation in the low-frequency band (4-20 Hz).Compared with the global signal of fMRI, the global signal of EEG provides more temporal information about outer cortical neural activity.These results provide new evidence for the electrophysiology information of the global signal of resting-state fMRI. More importantly, due to its high correlation with the fMRI global signal, the EEG global signal may serve as a new biomarker for neurological disorders." @default.
• W2890960891 created "2018-09-27" @default.
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• W2890960891 date "2019-01-01" @default.
• W2890960891 modified "2023-09-28" @default.
• W2890960891 title "Electrophysiological signatures of the resting-state fMRI global signal: A simultaneous EEG-fMRI study" @default.
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• W2890960891 doi "https://doi.org/10.1016/j.jneumeth.2018.09.017" @default.
• W2890960891 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30236777" @default.
• W2890960891 hasPublicationYear "2019" @default.
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