FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890963856> ?p ?o ?g. }

• W2890963856 abstract "10572 Background: Pediatric brain tumor survivors (PBTS) often have neurodevelopmental late effects, including attention and concentration deficits, which may impact cognitive and academic functioning. Such symptoms are also seen in attention-deficit/hyperactivity disorder (ADHD), which affects ~5-8% of children and adolescents. This study examined the prevalence of ADHD diagnosis and ADHD medication use in PBTS and identified higher risk subsets of patients. Methods: A retrospective chart review was completed of PBTS (n = 106), diagnosed from 1999-2013, who were at least 2 years from the end of tumor-directed therapy (surgery, chemotherapy and/or radiation therapy) and without a multi-system genetic disorder or severe developmental delay prior to brain tumor diagnosis. Subjects were already screened for or enrolled in 3 other studies of PBTS late effects. Statistical analysis involved chi-squared analysis. Results: Among the 106 patients, 55.7% were male, with an average age at time of brain tumor diagnosis of 5.9 years (0-12.2 years). The most common tumor types were glioma (51.9% with 47.2% low grade, 4.7% high grade), medulloblastoma (13.2%) and ependymoma (11.3%), with 50% of tumors supratentorial, 46.2% infratentorial and 3.8% either extending or multifocal across the tentorium. Of the patients, 42.5% received radiation therapy, 38.7% chemotherapy and 86.8% surgery. Nineteen patients (17.9%) had ADHD diagnoses, and 20 (18.9%) had been on ADHD medications. Clinical factors associated with an ADHD diagnosis were supratentorial vs. infratentorial tumors (28.3% vs. 6.1%, p = 0.013), no radiation therapy vs. radiation therapy (27.9% vs. 4.4%, p = 0.002) and no chemotherapy vs. chemotherapy (24.6% vs. 7.3%, p = 0.024). ADHD diagnosis was not associated with age of brain tumor diagnosis or surgical treatment. Conclusions: Our study suggests that PBTS have over twice the ADHD prevalence as the general population, most notably in patients with supratentorial tumors or without a history of radiation therapy or chemotherapy. The results suggest that a closer look at this population is warranted and that select patients may benefit from behavioral or pharmacologic ADHD treatments to optimize functioning." @default.
• W2890963856 created "2018-09-27" @default.
• W2890963856 creator A5014041718 @default.
• W2890963856 creator A5022414283 @default.
• W2890963856 creator A5042268823 @default.
• W2890963856 creator A5043479386 @default.
• W2890963856 creator A5068616242 @default.
• W2890963856 creator A5071493886 @default.
• W2890963856 creator A5079323221 @default.
• W2890963856 date "2017-05-20" @default.
• W2890963856 modified "2023-09-22" @default.
• W2890963856 title "Prevalence of attention-deficit/hyperactivity disorder in pediatric brain tumor survivors." @default.
• W2890963856 doi "https://doi.org/10.1200/jco.2017.35.15_suppl.10572" @default.
• W2890963856 hasPublicationYear "2017" @default.
• W2890963856 type Work @default.
• W2890963856 sameAs 2890963856 @default.
• W2890963856 citedByCount "1" @default.
• W2890963856 countsByYear W28909638562021 @default.
• W2890963856 crossrefType "journal-article" @default.
• W2890963856 hasAuthorship W2890963856A5014041718 @default.
• W2890963856 hasAuthorship W2890963856A5022414283 @default.
• W2890963856 hasAuthorship W2890963856A5042268823 @default.
• W2890963856 hasAuthorship W2890963856A5043479386 @default.
• W2890963856 hasAuthorship W2890963856A5068616242 @default.
• W2890963856 hasAuthorship W2890963856A5071493886 @default.
• W2890963856 hasAuthorship W2890963856A5079323221 @default.
• W2890963856 hasConcept C118552586 @default.
• W2890963856 hasConcept C187212893 @default.
• W2890963856 hasConcept C2779130545 @default.
• W2890963856 hasConcept C2780783007 @default.
• W2890963856 hasConcept C71924100 @default.
• W2890963856 hasConceptScore W2890963856C118552586 @default.
• W2890963856 hasConceptScore W2890963856C187212893 @default.
• W2890963856 hasConceptScore W2890963856C2779130545 @default.
• W2890963856 hasConceptScore W2890963856C2780783007 @default.
• W2890963856 hasConceptScore W2890963856C71924100 @default.
• W2890963856 hasLocation W28909638561 @default.
• W2890963856 hasOpenAccess W2890963856 @default.
• W2890963856 hasPrimaryLocation W28909638561 @default.
• W2890963856 hasRelatedWork W1494738062 @default.
• W2890963856 hasRelatedWork W193972968 @default.
• W2890963856 hasRelatedWork W1984035518 @default.
• W2890963856 hasRelatedWork W1987656230 @default.
• W2890963856 hasRelatedWork W1992881167 @default.
• W2890963856 hasRelatedWork W2043872587 @default.
• W2890963856 hasRelatedWork W2089877025 @default.
• W2890963856 hasRelatedWork W2093795238 @default.
• W2890963856 hasRelatedWork W2110424029 @default.
• W2890963856 hasRelatedWork W2252380495 @default.
• W2890963856 hasRelatedWork W2267543788 @default.
• W2890963856 hasRelatedWork W2322245026 @default.
• W2890963856 hasRelatedWork W2468332286 @default.
• W2890963856 hasRelatedWork W2535103611 @default.
• W2890963856 hasRelatedWork W2535532769 @default.
• W2890963856 hasRelatedWork W2538387981 @default.
• W2890963856 hasRelatedWork W2750340973 @default.
• W2890963856 hasRelatedWork W3030678719 @default.
• W2890963856 hasRelatedWork W3118637899 @default.
• W2890963856 hasRelatedWork W3181996250 @default.
• W2890963856 isParatext "false" @default.
• W2890963856 isRetracted "false" @default.
• W2890963856 magId "2890963856" @default.
• W2890963856 workType "article" @default.