Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890966814> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W2890966814 abstract "In 4% of cases, venous thromboembolism (VTE) involves organ‑related venous territories such as splanchnic, renal, gonadal, and cerebral venous segments, and is often called venous thromboembolism of atypical location (VTE‑AL). Recommendations regarding the method, intensity, and duration of anticoagulant therapy for VTE‑AL are not well established. Direct oral anticoagulants (DOACs) have been a promising alternative to vitamin K antagonists in the treatment of acute VTE. However, all major clinical trials on DOACs excluded patients with VTE‑AL. Therefore, data on the use of DOACs in patients with VTE‑AL are still limited to case reports and small clinical series, with a relative predominance of publications on splanchnic vein thrombosis including mesenteric, splenic, portal, and hepatic vein thrombosis. The only randomized clinical trial comparing a clinical outcome of patients with acute portal vein thrombosis randomized to either rivaroxaban or warfarin treatment yielded significantly impaired results due to the use of an atypical rivaroxaban dose. A prospective registration of clinical outcome for DOACs used in patients with VTE‑AL, in those with VTE of typical location, and in those with VTE‑AL treated with enoxaparin showed similar VTE recurrence and major bleeding rates in all 3 groups. High cancer prevalence, typical for VTE‑AL, significantly impacted survival as well as VTE recurrence rates and major bleeding outcomes in this study. In general, although still limited, the results for DOAC use in VTE‑AL are encouraging and we do not hesitate to use DOACs, particularly rivaroxaban or apixaban, in selected patients with VTE‑AL." @default.
- W2890966814 created "2018-09-27" @default.
- W2890966814 creator A5001973235 @default.
- W2890966814 creator A5017032740 @default.
- W2890966814 creator A5022532011 @default.
- W2890966814 creator A5050586204 @default.
- W2890966814 creator A5060027910 @default.
- W2890966814 date "2018-09-20" @default.
- W2890966814 modified "2023-10-18" @default.
- W2890966814 title "Thrombosis of atypical location: how to treat patients in the era of direct oral anticoagulants?" @default.
- W2890966814 doi "https://doi.org/10.20452/pamw.4333" @default.
- W2890966814 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30233080" @default.
- W2890966814 hasPublicationYear "2018" @default.
- W2890966814 type Work @default.
- W2890966814 sameAs 2890966814 @default.
- W2890966814 citedByCount "1" @default.
- W2890966814 countsByYear W28909668142020 @default.
- W2890966814 crossrefType "journal-article" @default.
- W2890966814 hasAuthorship W2890966814A5001973235 @default.
- W2890966814 hasAuthorship W2890966814A5017032740 @default.
- W2890966814 hasAuthorship W2890966814A5022532011 @default.
- W2890966814 hasAuthorship W2890966814A5050586204 @default.
- W2890966814 hasAuthorship W2890966814A5060027910 @default.
- W2890966814 hasBestOaLocation W28909668141 @default.
- W2890966814 hasConcept C126322002 @default.
- W2890966814 hasConcept C141071460 @default.
- W2890966814 hasConcept C168563851 @default.
- W2890966814 hasConcept C2776301958 @default.
- W2890966814 hasConcept C2778205648 @default.
- W2890966814 hasConcept C2778661090 @default.
- W2890966814 hasConcept C2779161974 @default.
- W2890966814 hasConcept C2780011451 @default.
- W2890966814 hasConcept C2780638905 @default.
- W2890966814 hasConcept C2780868729 @default.
- W2890966814 hasConcept C71924100 @default.
- W2890966814 hasConceptScore W2890966814C126322002 @default.
- W2890966814 hasConceptScore W2890966814C141071460 @default.
- W2890966814 hasConceptScore W2890966814C168563851 @default.
- W2890966814 hasConceptScore W2890966814C2776301958 @default.
- W2890966814 hasConceptScore W2890966814C2778205648 @default.
- W2890966814 hasConceptScore W2890966814C2778661090 @default.
- W2890966814 hasConceptScore W2890966814C2779161974 @default.
- W2890966814 hasConceptScore W2890966814C2780011451 @default.
- W2890966814 hasConceptScore W2890966814C2780638905 @default.
- W2890966814 hasConceptScore W2890966814C2780868729 @default.
- W2890966814 hasConceptScore W2890966814C71924100 @default.
- W2890966814 hasLocation W28909668141 @default.
- W2890966814 hasLocation W28909668142 @default.
- W2890966814 hasOpenAccess W2890966814 @default.
- W2890966814 hasPrimaryLocation W28909668141 @default.
- W2890966814 hasRelatedWork W1980555552 @default.
- W2890966814 hasRelatedWork W2181601210 @default.
- W2890966814 hasRelatedWork W2522940703 @default.
- W2890966814 hasRelatedWork W2576538605 @default.
- W2890966814 hasRelatedWork W2741829680 @default.
- W2890966814 hasRelatedWork W2895090492 @default.
- W2890966814 hasRelatedWork W2908436399 @default.
- W2890966814 hasRelatedWork W3032158384 @default.
- W2890966814 hasRelatedWork W3202697683 @default.
- W2890966814 hasRelatedWork W18947196 @default.
- W2890966814 isParatext "false" @default.
- W2890966814 isRetracted "false" @default.
- W2890966814 magId "2890966814" @default.
- W2890966814 workType "article" @default.