FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890967653> ?p ?o ?g. }

• W2890967653 endingPage "13364" @default.
• W2890967653 startingPage "13356" @default.
• W2890967653 abstract "Metallic plasmonic nanoparticles have been intensively exploited as theranostic nanoprobes for plasmonic photothermal therapy (PPT) and surface-enhanced Raman spectroscopy (SERS) applications. But the underlying molecular mechanisms associated with PPT-induced apoptosis between cancerous and normal cells have remained largely unknown or disputed. In this study, we designed an organelle-targeting theranostic plasmonic SERS nanoprobe (CDs-Ag/Au NS) composed of porous Ag/Au nanoshell (p-Ag/Au NSs) and carbon dots (CDs) for nucleus and mitochondria targeted PPT of cells. The differences in molecular stress response in the PPT-induced hyperthermia cell death between cancerous HeLa and normal L929 and H8 cells have been revealed by site-specific single-cell SERS detection. The contents of tryptophan (Trp), phenylalanine (Phe), and tyrosine (Tyr) in HeLa cells were found more evidently increased than L929 and H8 cells during the PPT-induced cell-death process. And from the mitochondria point of view, we found that the PPT-induced cell apoptosis for HeLa cells mainly stems from (or is regulated through) cellular thermal stress-responsive proteins, while for L929 and H8 cells it seems more related to DNA. Understanding molecular stress response difference of the PPT-induced cell apoptosis between cancerous and normal cells is helpful for diagnosis and treatment of cancer, and the method will open an avenue for single-cell studies." @default.
• W2890967653 created "2018-09-27" @default.
• W2890967653 creator A5014507212 @default.
• W2890967653 creator A5036477294 @default.
• W2890967653 creator A5051638447 @default.
• W2890967653 creator A5061492245 @default.
• W2890967653 creator A5077991750 @default.
• W2890967653 creator A5088230867 @default.
• W2890967653 creator A5091068751 @default.
• W2890967653 date "2018-09-20" @default.
• W2890967653 modified "2023-10-16" @default.
• W2890967653 title "Nucleus and Mitochondria Targeting Theranostic Plasmonic Surface-Enhanced Raman Spectroscopy Nanoprobes as a Means for Revealing Molecular Stress Response Differences in Hyperthermia Cell Death between Cancerous and Normal Cells" @default.
• W2890967653 cites W1499520031 @default.
• W2890967653 cites W1967552758 @default.
• W2890967653 cites W1973724012 @default.
• W2890967653 cites W1974872259 @default.
• W2890967653 cites W1975542665 @default.
• W2890967653 cites W1991326083 @default.
• W2890967653 cites W2005282401 @default.
• W2890967653 cites W2019704138 @default.
• W2890967653 cites W2024437068 @default.
• W2890967653 cites W2026377074 @default.
• W2890967653 cites W2031868133 @default.
• W2890967653 cites W2059118972 @default.
• W2890967653 cites W2073560519 @default.
• W2890967653 cites W2084444257 @default.
• W2890967653 cites W2101747542 @default.
• W2890967653 cites W2117560166 @default.
• W2890967653 cites W2129166766 @default.
• W2890967653 cites W2129402323 @default.
• W2890967653 cites W2144277227 @default.
• W2890967653 cites W2150142090 @default.
• W2890967653 cites W2161908857 @default.
• W2890967653 cites W2221608863 @default.
• W2890967653 cites W2227038956 @default.
• W2890967653 cites W2286416881 @default.
• W2890967653 cites W2312941501 @default.
• W2890967653 cites W2319084466 @default.
• W2890967653 cites W2319288524 @default.
• W2890967653 cites W2329451034 @default.
• W2890967653 cites W2475831462 @default.
• W2890967653 cites W2541962310 @default.
• W2890967653 cites W2547935001 @default.
• W2890967653 cites W2559787613 @default.
• W2890967653 cites W2611800801 @default.
• W2890967653 cites W2697114027 @default.
• W2890967653 cites W2728985030 @default.
• W2890967653 cites W2762246063 @default.
• W2890967653 cites W2801099111 @default.
• W2890967653 cites W2950530527 @default.
• W2890967653 cites W4236961487 @default.
• W2890967653 doi "https://doi.org/10.1021/acs.analchem.8b03034" @default.
• W2890967653 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30234969" @default.
• W2890967653 hasPublicationYear "2018" @default.
• W2890967653 type Work @default.
• W2890967653 sameAs 2890967653 @default.
• W2890967653 citedByCount "43" @default.
• W2890967653 countsByYear W28909676532019 @default.
• W2890967653 countsByYear W28909676532020 @default.
• W2890967653 countsByYear W28909676532021 @default.
• W2890967653 countsByYear W28909676532022 @default.
• W2890967653 countsByYear W28909676532023 @default.
• W2890967653 crossrefType "journal-article" @default.
• W2890967653 hasAuthorship W2890967653A5014507212 @default.
• W2890967653 hasAuthorship W2890967653A5036477294 @default.
• W2890967653 hasAuthorship W2890967653A5051638447 @default.
• W2890967653 hasAuthorship W2890967653A5061492245 @default.
• W2890967653 hasAuthorship W2890967653A5077991750 @default.
• W2890967653 hasAuthorship W2890967653A5088230867 @default.
• W2890967653 hasAuthorship W2890967653A5091068751 @default.
• W2890967653 hasConcept C121608353 @default.
• W2890967653 hasConcept C12554922 @default.
• W2890967653 hasConcept C1491633281 @default.
• W2890967653 hasConcept C155672457 @default.
• W2890967653 hasConcept C16387964 @default.
• W2890967653 hasConcept C168240541 @default.
• W2890967653 hasConcept C171250308 @default.
• W2890967653 hasConcept C182606246 @default.
• W2890967653 hasConcept C185592680 @default.
• W2890967653 hasConcept C190062978 @default.
• W2890967653 hasConcept C190283241 @default.
• W2890967653 hasConcept C192562407 @default.
• W2890967653 hasConcept C2777366897 @default.
• W2890967653 hasConcept C28859421 @default.
• W2890967653 hasConcept C31573885 @default.
• W2890967653 hasConcept C33197981 @default.
• W2890967653 hasConcept C54355233 @default.
• W2890967653 hasConcept C55493867 @default.
• W2890967653 hasConcept C86803240 @default.
• W2890967653 hasConcept C95444343 @default.
• W2890967653 hasConcept C96232424 @default.
• W2890967653 hasConceptScore W2890967653C121608353 @default.
• W2890967653 hasConceptScore W2890967653C12554922 @default.
• W2890967653 hasConceptScore W2890967653C1491633281 @default.
• W2890967653 hasConceptScore W2890967653C155672457 @default.
• W2890967653 hasConceptScore W2890967653C16387964 @default.
• W2890967653 hasConceptScore W2890967653C168240541 @default.
• W2890967653 hasConceptScore W2890967653C171250308 @default.

• next