Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890974080> ?p ?o ?g. }
- W2890974080 endingPage "196" @default.
- W2890974080 startingPage "182" @default.
- W2890974080 abstract "Background: Horizontal gene transfer of mobile genetic elements is an essential component of prokaryotic evolution. These insertion events in eukaryotes and particularly in the human genome have been investigated by various methodologies with varying results. Objective: In this paper, we implement a sequence composition approach to investigate insertions of genomic islands in the human genome. Methods: A modified version of a prokaryotic GI identifier, SeqWord Gene Island Sniffer v.2.0, was used to predict genomic islands in the hg38 version of the human genome. Results: Predicted genomic islands were enriched with long non-coding RNAs and also contributed to the acquisition and modification of proteins associated with the immune system and gonad development, albeit to a lesser extent. The estimated rate of acquisition of these genomic islands in vertebrate genomes was non-linear with regards to species divergence times with an acceleration at the time of vertebrate land invasion and during the transition of prosimians to monkeys soon after the Cretaceous-Paleogene extinction. Conclusion: The rapid acquisition of non-conserved long non-coding RNAs in the human genome and probably in vertebrata genomes was facilitated by horizontal gene transfer. All predicted human genomic islands and supporting information are freely accessible from http://hislands.bi.up.ac.za ." @default.
- W2890974080 created "2018-09-27" @default.
- W2890974080 creator A5007808396 @default.
- W2890974080 creator A5018683773 @default.
- W2890974080 creator A5075129627 @default.
- W2890974080 creator A5079610290 @default.
- W2890974080 date "2018-08-31" @default.
- W2890974080 modified "2023-10-17" @default.
- W2890974080 title "Long Non-coding RNAs in the Human Genome Acquired by Horizontal Gene Transfer" @default.
- W2890974080 cites W1964752634 @default.
- W2890974080 cites W1987592711 @default.
- W2890974080 cites W1998787456 @default.
- W2890974080 cites W2002773642 @default.
- W2890974080 cites W2004852601 @default.
- W2890974080 cites W2018267268 @default.
- W2890974080 cites W2029868997 @default.
- W2890974080 cites W2032183472 @default.
- W2890974080 cites W2034285706 @default.
- W2890974080 cites W2042606720 @default.
- W2890974080 cites W2047301149 @default.
- W2890974080 cites W2055043387 @default.
- W2890974080 cites W2068603584 @default.
- W2890974080 cites W2091161969 @default.
- W2890974080 cites W2096465161 @default.
- W2890974080 cites W2107678755 @default.
- W2890974080 cites W2108923274 @default.
- W2890974080 cites W2110859934 @default.
- W2890974080 cites W2111647009 @default.
- W2890974080 cites W2113824405 @default.
- W2890974080 cites W2116326559 @default.
- W2890974080 cites W2119440591 @default.
- W2890974080 cites W2121166240 @default.
- W2890974080 cites W2124788609 @default.
- W2890974080 cites W2127230663 @default.
- W2890974080 cites W2128664117 @default.
- W2890974080 cites W2129375421 @default.
- W2890974080 cites W2135090321 @default.
- W2890974080 cites W2136220556 @default.
- W2890974080 cites W2137678717 @default.
- W2890974080 cites W2151183612 @default.
- W2890974080 cites W2155781491 @default.
- W2890974080 cites W2158007484 @default.
- W2890974080 cites W2158847524 @default.
- W2890974080 cites W2160378127 @default.
- W2890974080 cites W2162640876 @default.
- W2890974080 cites W2165697084 @default.
- W2890974080 cites W2168909179 @default.
- W2890974080 cites W2197795100 @default.
- W2890974080 cites W2304080550 @default.
- W2890974080 cites W2326956261 @default.
- W2890974080 cites W2336330109 @default.
- W2890974080 cites W2464717012 @default.
- W2890974080 cites W2511664109 @default.
- W2890974080 cites W2559466477 @default.
- W2890974080 cites W2597983922 @default.
- W2890974080 cites W2604308930 @default.
- W2890974080 cites W2604530975 @default.
- W2890974080 cites W2612061632 @default.
- W2890974080 cites W2759159973 @default.
- W2890974080 cites W2802495987 @default.
- W2890974080 cites W4234797890 @default.
- W2890974080 cites W2566220750 @default.
- W2890974080 doi "https://doi.org/10.2174/1875036201811010182" @default.
- W2890974080 hasPublicationYear "2018" @default.
- W2890974080 type Work @default.
- W2890974080 sameAs 2890974080 @default.
- W2890974080 citedByCount "1" @default.
- W2890974080 countsByYear W28909740802022 @default.
- W2890974080 crossrefType "journal-article" @default.
- W2890974080 hasAuthorship W2890974080A5007808396 @default.
- W2890974080 hasAuthorship W2890974080A5018683773 @default.
- W2890974080 hasAuthorship W2890974080A5075129627 @default.
- W2890974080 hasAuthorship W2890974080A5079610290 @default.
- W2890974080 hasBestOaLocation W28909740801 @default.
- W2890974080 hasConcept C104317684 @default.
- W2890974080 hasConcept C132533263 @default.
- W2890974080 hasConcept C141231307 @default.
- W2890974080 hasConcept C174600577 @default.
- W2890974080 hasConcept C189206191 @default.
- W2890974080 hasConcept C197077220 @default.
- W2890974080 hasConcept C2778961482 @default.
- W2890974080 hasConcept C54355233 @default.
- W2890974080 hasConcept C70721500 @default.
- W2890974080 hasConcept C78458016 @default.
- W2890974080 hasConcept C86803240 @default.
- W2890974080 hasConcept C92938381 @default.
- W2890974080 hasConceptScore W2890974080C104317684 @default.
- W2890974080 hasConceptScore W2890974080C132533263 @default.
- W2890974080 hasConceptScore W2890974080C141231307 @default.
- W2890974080 hasConceptScore W2890974080C174600577 @default.
- W2890974080 hasConceptScore W2890974080C189206191 @default.
- W2890974080 hasConceptScore W2890974080C197077220 @default.
- W2890974080 hasConceptScore W2890974080C2778961482 @default.
- W2890974080 hasConceptScore W2890974080C54355233 @default.
- W2890974080 hasConceptScore W2890974080C70721500 @default.
- W2890974080 hasConceptScore W2890974080C78458016 @default.
- W2890974080 hasConceptScore W2890974080C86803240 @default.
- W2890974080 hasConceptScore W2890974080C92938381 @default.