FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890977428> ?p ?o ?g. }

• W2890977428 endingPage "2760" @default.
• W2890977428 startingPage "2760" @default.
• W2890977428 abstract "This study investigated the relationship between clinical severity and percentage of conjunctival antigen-presenting cells (APCs) in Sjögren’s syndrome (SS)-associated keratoconjunctivitis sicca (KCS). KCS clinical severity was based on symptom severity, tear volume, tear break-up time, and ocular surface dye staining. Conjunctival goblet cell density (GCD) was measured in periodic acid Schiff (PAS)-stained membranes. Conjunctival cells obtained by impression cytology were used for flow cytometry to measure percentages of CD45+HLA-DR+ APCs and mature CD11c+CD86+ dendritic cells (DCs). Compared to normal conjunctiva, the percentages of HLA-DR+ and CD11c+CD86+ cells were higher in the conjunctiva of the KCS group (p < 0.05). The percentage of CD45+HLA-DR+ cells positively correlated with clinical severity (r = 0.71, p < 0.05) and negatively correlated with GCD (r = −0.61, p < 0.05). Clinical severity also negatively correlated with GCD (r = −0.54, p < 0.05). These findings indicate that a higher percentage of APCs and mature DCs in the conjunctiva is associated with more severe KCS in SS. These APCs may contribute to the generation of the pathogenic Th1 cells that cause goblet cell loss in KCS." @default.
• W2890977428 created "2018-09-27" @default.
• W2890977428 creator A5024092541 @default.
• W2890977428 creator A5027119261 @default.
• W2890977428 creator A5037905663 @default.
• W2890977428 creator A5049004483 @default.
• W2890977428 creator A5067942686 @default.
• W2890977428 creator A5086607086 @default.
• W2890977428 date "2018-09-14" @default.
• W2890977428 modified "2023-10-14" @default.
• W2890977428 title "Severity of Sjögren’s Syndrome Keratoconjunctivitis Sicca Increases with Increased Percentage of Conjunctival Antigen-Presenting Cells" @default.
• W2890977428 cites W112689046 @default.
• W2890977428 cites W1552158380 @default.
• W2890977428 cites W159017383 @default.
• W2890977428 cites W1966322383 @default.
• W2890977428 cites W1967999929 @default.
• W2890977428 cites W1969801895 @default.
• W2890977428 cites W1978045632 @default.
• W2890977428 cites W2002180108 @default.
• W2890977428 cites W2005970215 @default.
• W2890977428 cites W2020078559 @default.
• W2890977428 cites W2037403388 @default.
• W2890977428 cites W2045561656 @default.
• W2890977428 cites W2049207532 @default.
• W2890977428 cites W2050571098 @default.
• W2890977428 cites W2052525810 @default.
• W2890977428 cites W2059577729 @default.
• W2890977428 cites W2074357311 @default.
• W2890977428 cites W2086358431 @default.
• W2890977428 cites W2092033904 @default.
• W2890977428 cites W2099574567 @default.
• W2890977428 cites W2121635719 @default.
• W2890977428 cites W2122121998 @default.
• W2890977428 cites W2126358511 @default.
• W2890977428 cites W2142263640 @default.
• W2890977428 cites W2169772679 @default.
• W2890977428 cites W2195529641 @default.
• W2890977428 cites W2338923707 @default.
• W2890977428 cites W2611039653 @default.
• W2890977428 cites W2735954633 @default.
• W2890977428 cites W2765242879 @default.
• W2890977428 cites W2787592352 @default.
• W2890977428 cites W2843305576 @default.
• W2890977428 doi "https://doi.org/10.3390/ijms19092760" @default.
• W2890977428 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6165102" @default.
• W2890977428 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30223431" @default.
• W2890977428 hasPublicationYear "2018" @default.
• W2890977428 type Work @default.
• W2890977428 sameAs 2890977428 @default.
• W2890977428 citedByCount "29" @default.
• W2890977428 countsByYear W28909774282019 @default.
• W2890977428 countsByYear W28909774282020 @default.
• W2890977428 countsByYear W28909774282021 @default.
• W2890977428 countsByYear W28909774282022 @default.
• W2890977428 countsByYear W28909774282023 @default.
• W2890977428 crossrefType "journal-article" @default.
• W2890977428 hasAuthorship W2890977428A5024092541 @default.
• W2890977428 hasAuthorship W2890977428A5027119261 @default.
• W2890977428 hasAuthorship W2890977428A5037905663 @default.
• W2890977428 hasAuthorship W2890977428A5049004483 @default.
• W2890977428 hasAuthorship W2890977428A5067942686 @default.
• W2890977428 hasAuthorship W2890977428A5086607086 @default.
• W2890977428 hasBestOaLocation W28909774281 @default.
• W2890977428 hasConcept C104317684 @default.
• W2890977428 hasConcept C118487528 @default.
• W2890977428 hasConcept C127716648 @default.
• W2890977428 hasConcept C142724271 @default.
• W2890977428 hasConcept C147483822 @default.
• W2890977428 hasConcept C16005928 @default.
• W2890977428 hasConcept C203014093 @default.
• W2890977428 hasConcept C2775941134 @default.
• W2890977428 hasConcept C2775984611 @default.
• W2890977428 hasConcept C2776090121 @default.
• W2890977428 hasConcept C2776469317 @default.
• W2890977428 hasConcept C2776882836 @default.
• W2890977428 hasConcept C2778064476 @default.
• W2890977428 hasConcept C2778170410 @default.
• W2890977428 hasConcept C2778918178 @default.
• W2890977428 hasConcept C2779919695 @default.
• W2890977428 hasConcept C2781101188 @default.
• W2890977428 hasConcept C529295009 @default.
• W2890977428 hasConcept C553184892 @default.
• W2890977428 hasConcept C55493867 @default.
• W2890977428 hasConcept C71924100 @default.
• W2890977428 hasConcept C86803240 @default.
• W2890977428 hasConcept C8891405 @default.
• W2890977428 hasConceptScore W2890977428C104317684 @default.
• W2890977428 hasConceptScore W2890977428C118487528 @default.
• W2890977428 hasConceptScore W2890977428C127716648 @default.
• W2890977428 hasConceptScore W2890977428C142724271 @default.
• W2890977428 hasConceptScore W2890977428C147483822 @default.
• W2890977428 hasConceptScore W2890977428C16005928 @default.
• W2890977428 hasConceptScore W2890977428C203014093 @default.
• W2890977428 hasConceptScore W2890977428C2775941134 @default.
• W2890977428 hasConceptScore W2890977428C2775984611 @default.
• W2890977428 hasConceptScore W2890977428C2776090121 @default.
• W2890977428 hasConceptScore W2890977428C2776469317 @default.
• W2890977428 hasConceptScore W2890977428C2776882836 @default.

• next