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• W2891009007 abstract "INTRODUCTION: Diabetic retinopathy (DR) is a microvascular complication ofboth type I and type II diabetes mellitus (DM) has become one of theleading causes of blindness world wide (Wilkinson 1988)1. It is apreventable blindness. DR is due to microangiopathy affecting the precapillary arterioles, capillaries and venules. Macular edema is an important and complex component of Nonproliferative diabetic retinopathy (NPDR) and Proliferative diabeticretinopathy (PDR) and is the major cause of impaired vision. This studyfocusses on the role of Fundus Fluorescein Angiography (FFA) andOptical Coherence Tomography (OCT) in diabetic macular edema andits management. AIM OF THE STUDY: To study the prevalence of diabetic maculopathy in relation to age, gender, duration of diabetes mellitus.To classify diabetic maculopathy using FFA & OCTTo treat diabetic maculopathy according to FFA & OCTclassification.To monitor the response to treatment with OCT.MATERIALS AND METHODS: This study was conducted in Regional Institute of Ophthalmology AndGovernment Ophthalmic Hospital, Egmore, Chennai from November 2009 toNovember 2011 for a period of 24 months.INCLUSION CRITERIA:All patients with clinically significant macular edema and withcentral subfield macular thickness more than 200 microns.EXCLUSION CRITERIA:i. History of severe systemic disease/steroidsii. Uncontrolled Diabetes mellitus/Hypertensioniii. Any condition affecting follow up.iv. History of associated glaucoma/ocular hypertensionv. History or evidence of ongoing uveitisvi. Advanced diabetic eye diseaseAll the patients were taken a brief history and subjected to detailed systemicand ophthalmic examination. Anterior segment examination with slit lampbiomicroscope and posterior segment examination using 90 D, binocular indirectophthalmoscope. Fundus photograph was also taken for documentation. Fundusfluorescein angiography, Optical coherence tomography were done for all patients.DISCUSSION:Diabetic macular edema is the major cause of visual morbidity in diabeticpatients. The laser treatment given by ETDRS remains the standard therapy ofDME. Focal and diffuse types of leaks diagnosed on FFA were treated with focaland grid laser. Cystoid type and recalcitrant type of macular edema not respondingto laser treatment were given injection IVTA.CONCLUSION: In our hospital 100 eyes of 50 patients were studied during NOVEMBER2009 to NOVEMBER 2011. The incidence of diabetic maculopathy is found to becommoner in the middle age group of 40-60 years the majority were males and theincidence of diabetic maculopathy increased with the increase in duration ofdiabetes.Among the FFA patterns focal leaks were commoner and in OCT spongyedema were the common types. Patients who had ischemic type of maculopathywere kept under observation and had the worst prognosis over time. The majority offocal leaks improved with focal laser, and diffuse leaks with grid laser. Andmajority of recalcitrant types of macular edema and cystoid type showedimprovement with IVTA injection. Patients with ischemic maculopathy in FFA andVMT & TPH in OCT had the worst visual prognosisThe overall improvement in visual acuity and the reduction in the macularthickness was detected and documented by OCT. FFA helped in detecting thespecific leakage patterns and to decide the type of laser treatment. OCT aids indetecting subtle macular edema that may be difficult to detect on slit lampbiomicroscopy and in documenting the treatment response. and monitoring theresponse to treatment more accurately and less invasively than FFA. OCT & FFAplay a major and complementary role in the diabetic maculopathy managementandfollow up." @default.
• W2891009007 created "2018-09-27" @default.
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• W2891009007 date "2012-04-01" @default.
• W2891009007 modified "2023-09-27" @default.
• W2891009007 title "Role of fundus fluorescein angiography and optical coherence tomography in diabetic maculopathy: A clinical study." @default.
• W2891009007 hasPublicationYear "2012" @default.
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