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• W2891009673 abstract "Negative self-referential thinking is a common symptom of depression associated with poor treatment response. In late-life depression, white matter abnormalities may contribute to negative self-referential thoughts following antidepressant treatment. We investigated the association of fractional anisotropy (FA) in select regions of the negative valence system (NVS) with residual negative self-referential thoughts following treatment with escitalopram for late-life depression. The participants were older adults with major depression and psychiatrically normal controls. Depressed participants received 12 weeks of treatment with escitalopram. To assess self-referential thinking, participants completed a Trait Adjective Task at baseline and at week 12. Baseline MRI scans included a diffusion imaging sequence for FA analyses. Participants with late-life depression differed from controls on all performance measures of the Trait Adjective Task at baseline and at 12 weeks. Depressed participants endorsed fewer negative personality traits and more positive personality traits at week 12 compared to baseline. Lower FA in the dorsal anterior cingulate and in the uncinate fasciculus in depressed participants was correlated with residual negative self-referential thinking (e.g., more endorsed negative adjectives, fewer rejected negative adjectives) at treatment end. The sample size is modest so the findings are preliminary. FA analyses were restricted to predetermined regions. Negative self-referential thinking improved in depressed older adults following 12 weeks of treatment with escitalopram. Baseline FA in select white matter regions of the NVS was associated with residual negative self-referential thinking. These findings may help identify treatment targets for residual negative self-referential thoughts." @default.
• W2891009673 created "2018-09-27" @default.
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• W2891009673 date "2019-01-01" @default.
• W2891009673 modified "2023-10-16" @default.
• W2891009673 title "White matter abnormalities predict residual negative self-referential thinking following treatment of late-life depression with escitalopram: A preliminary study" @default.
• W2891009673 cites W1536749812 @default.
• W2891009673 cites W1691197472 @default.
• W2891009673 cites W1704143532 @default.
• W2891009673 cites W1781131011 @default.
• W2891009673 cites W1795704345 @default.
• W2891009673 cites W1847168837 @default.
• W2891009673 cites W1868943479 @default.
• W2891009673 cites W1897377682 @default.
• W2891009673 cites W1897726106 @default.
• W2891009673 cites W1919325159 @default.
• W2891009673 cites W1963981093 @default.
• W2891009673 cites W1972428369 @default.
• W2891009673 cites W1978138377 @default.
• W2891009673 cites W1984262091 @default.
• W2891009673 cites W1987473536 @default.
• W2891009673 cites W1989696781 @default.
• W2891009673 cites W1994947322 @default.
• W2891009673 cites W1998992809 @default.
• W2891009673 cites W2001367656 @default.
• W2891009673 cites W2004506384 @default.
• W2891009673 cites W2004874491 @default.
• W2891009673 cites W2008353669 @default.
• W2891009673 cites W2008854521 @default.
• W2891009673 cites W2009684277 @default.
• W2891009673 cites W2012691107 @default.
• W2891009673 cites W2014210717 @default.
• W2891009673 cites W2017407197 @default.
• W2891009673 cites W2029286913 @default.
• W2891009673 cites W2036916152 @default.
• W2891009673 cites W2043118561 @default.
• W2891009673 cites W2047152236 @default.
• W2891009673 cites W2048103941 @default.
• W2891009673 cites W2050618347 @default.
• W2891009673 cites W2053883339 @default.
• W2891009673 cites W2056999109 @default.
• W2891009673 cites W2058161128 @default.
• W2891009673 cites W2058494291 @default.
• W2891009673 cites W2059318772 @default.
• W2891009673 cites W2063001897 @default.
• W2891009673 cites W2069163567 @default.
• W2891009673 cites W2072372317 @default.
• W2891009673 cites W2072919309 @default.
• W2891009673 cites W2078576494 @default.
• W2891009673 cites W2083488908 @default.
• W2891009673 cites W2084335923 @default.
• W2891009673 cites W2085097233 @default.
• W2891009673 cites W2085606083 @default.
• W2891009673 cites W2092676606 @default.
• W2891009673 cites W2092968073 @default.
• W2891009673 cites W2107342601 @default.
• W2891009673 cites W2110040374 @default.
• W2891009673 cites W2113895905 @default.
• W2891009673 cites W2114613490 @default.
• W2891009673 cites W2123542025 @default.
• W2891009673 cites W2125823313 @default.
• W2891009673 cites W2129600186 @default.
• W2891009673 cites W2131216563 @default.
• W2891009673 cites W2131398580 @default.
• W2891009673 cites W2131823335 @default.
• W2891009673 cites W2134189152 @default.
• W2891009673 cites W2135176444 @default.
• W2891009673 cites W2136148200 @default.
• W2891009673 cites W2137640133 @default.
• W2891009673 cites W2143594657 @default.
• W2891009673 cites W2145332605 @default.
• W2891009673 cites W2148080316 @default.
• W2891009673 cites W2150667092 @default.
• W2891009673 cites W2151712416 @default.
• W2891009673 cites W2152160545 @default.
• W2891009673 cites W2152817345 @default.
• W2891009673 cites W2155225268 @default.
• W2891009673 cites W2156152318 @default.
• W2891009673 cites W2156182436 @default.
• W2891009673 cites W2157481067 @default.
• W2891009673 cites W2157607979 @default.
• W2891009673 cites W2158327608 @default.
• W2891009673 cites W2162541816 @default.
• W2891009673 cites W2163816230 @default.
• W2891009673 cites W2167311298 @default.
• W2891009673 cites W2277786033 @default.
• W2891009673 cites W2339493577 @default.
• W2891009673 cites W247871665 @default.

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