FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891032444> ?p ?o ?g. }

• W2891032444 abstract "Background Hidradenitis suppurativa (HS) is a chronic debilitating inflammatory skin disease. Although HS and axial spondyloarthritis (SpA) share common denominators in the pathogenesis and treatment, little is known about HS associated patient characteristics in axial SpA. Objectives To identify patient characteristics associated with HS in a large cohort of axial SpA patients. Methods In this cross-sectional study, a self-screening questionnaire based on validated diagnostic HS questions was sent to all axial SpA patients from the Groningen Leeuwarden Axial Spondyloarthritis (GLAS) cohort. Verification of HS diagnosis was done by reviewing medical records for dermatologists diagnosis of HS and by telephone using another validated diagnostic HS question. These HS questions showed previously high sensitivity and specificity (92%–97%1 and 97%2, resp.). Comparative analysis for axial SpA patients with versus without HS was performed. Multivariable logistic regression analysis of patient characteristics was performed to investigate independent predictors for HS in axial SpA. Results In total, 75.6% (449/592) questionnaires were eligible for analyses. Included patients had a mean age of 50±13 years, 63% were male, mean symptom duration was 23±13 years, and 78% were HLA-B27 positive. HS diagnosis could be confirmed in 41 of the 449 respondents, resulting in an estimated prevalence of 9.1%. Assuming that all non-responders never had HS, the minimal HS prevalence rate would be 6.9% (41/592). In comparison to patients without a positive history of HS, these patients were more frequently female (54% vs. 35%, p=0.02), showed higher axial SpA disease activity (mean BASDAI 4.5 vs. 3.6, p=0.01 and ASDASCRP2.6 vs. 2.2 p=0.003), and worse quality of life (QoL) (median ASQoL 9.0 vs. 4.0, p Conclusions In our cohort of axial SpA patients, HS is more prevalent than in the general population (6.9%–9.1% and ~1% resp.).3 HS is associated with high ASDAS, especially in female patients experiencing poor QoL. Additionally, heel enthesitis and dactylitis seems also to be more prevalent in axial SpA patients with HS. References [1] Esmann S, et al. Questionnaire-based diagnosis of hidradenitis suppurativa: Specificity, sensitivity and positive predictive value of specific diagnostic questions. Br J Dermatol2010;163:102–6. [2] Vinding GR, et al. The prevalence of inverse recurrent suppuration: A population-based study of possible hidradenitis suppurativa. Br J Dermatol2014;170:884–9. [3] Miller IM, et al. Prevalence, risk factors, and comorbidities of hidradenitis suppurativa. Dermatologic Clinics2016;34:7–16. Disclosure of Interest A. Rondags: None declared, S. Arends Grant/research support from: Pfizer, F. Wink Consultant for: Abbvie, B. Horvath Grant/research support from: Abbvie, Janssen-Cilag, Novartis, Consultant for: Abbvie, Janssen-Cilag, Novartis, A. Spoorenberg Grant/research support from: Pfizer, Abbvie, Consultant for: Pfizer, Abbvie, MSD, UCB, Novartis" @default.
• W2891032444 created "2018-09-27" @default.
• W2891032444 creator A5045187079 @default.
• W2891032444 creator A5046964429 @default.
• W2891032444 creator A5052378583 @default.
• W2891032444 creator A5052491189 @default.
• W2891032444 creator A5066306670 @default.
• W2891032444 date "2018-06-01" @default.
• W2891032444 modified "2023-10-14" @default.
• W2891032444 title "FRI0184 High prevalence of hidradenitis suppurativa, especially in female axial spondyloarthritis patients with high disease activity and poor quality of life" @default.
• W2891032444 doi "https://doi.org/10.1136/annrheumdis-2018-eular.6379" @default.
• W2891032444 hasPublicationYear "2018" @default.
• W2891032444 type Work @default.
• W2891032444 sameAs 2891032444 @default.
• W2891032444 citedByCount "0" @default.
• W2891032444 crossrefType "proceedings-article" @default.
• W2891032444 hasAuthorship W2891032444A5045187079 @default.
• W2891032444 hasAuthorship W2891032444A5046964429 @default.
• W2891032444 hasAuthorship W2891032444A5052378583 @default.
• W2891032444 hasAuthorship W2891032444A5052491189 @default.
• W2891032444 hasAuthorship W2891032444A5066306670 @default.
• W2891032444 hasBestOaLocation W28910324441 @default.
• W2891032444 hasConcept C126322002 @default.
• W2891032444 hasConcept C151956035 @default.
• W2891032444 hasConcept C159110408 @default.
• W2891032444 hasConcept C2776002364 @default.
• W2891032444 hasConcept C2776213234 @default.
• W2891032444 hasConcept C2778579456 @default.
• W2891032444 hasConcept C2779134260 @default.
• W2891032444 hasConcept C2779951463 @default.
• W2891032444 hasConcept C71924100 @default.
• W2891032444 hasConcept C72563966 @default.
• W2891032444 hasConceptScore W2891032444C126322002 @default.
• W2891032444 hasConceptScore W2891032444C151956035 @default.
• W2891032444 hasConceptScore W2891032444C159110408 @default.
• W2891032444 hasConceptScore W2891032444C2776002364 @default.
• W2891032444 hasConceptScore W2891032444C2776213234 @default.
• W2891032444 hasConceptScore W2891032444C2778579456 @default.
• W2891032444 hasConceptScore W2891032444C2779134260 @default.
• W2891032444 hasConceptScore W2891032444C2779951463 @default.
• W2891032444 hasConceptScore W2891032444C71924100 @default.
• W2891032444 hasConceptScore W2891032444C72563966 @default.
• W2891032444 hasLocation W28910324441 @default.
• W2891032444 hasOpenAccess W2891032444 @default.
• W2891032444 hasPrimaryLocation W28910324441 @default.
• W2891032444 hasRelatedWork W2327099594 @default.
• W2891032444 hasRelatedWork W2328672514 @default.
• W2891032444 hasRelatedWork W2410744257 @default.
• W2891032444 hasRelatedWork W2412587704 @default.
• W2891032444 hasRelatedWork W2551043399 @default.
• W2891032444 hasRelatedWork W2751174559 @default.
• W2891032444 hasRelatedWork W2755124528 @default.
• W2891032444 hasRelatedWork W2907879858 @default.
• W2891032444 hasRelatedWork W2909238419 @default.
• W2891032444 hasRelatedWork W2945673464 @default.
• W2891032444 hasRelatedWork W2951301189 @default.
• W2891032444 hasRelatedWork W2953191327 @default.
• W2891032444 hasRelatedWork W2994911454 @default.
• W2891032444 hasRelatedWork W3025919826 @default.
• W2891032444 hasRelatedWork W3035753961 @default.
• W2891032444 hasRelatedWork W3044947860 @default.
• W2891032444 hasRelatedWork W3046770132 @default.
• W2891032444 hasRelatedWork W3093421176 @default.
• W2891032444 hasRelatedWork W3094119298 @default.
• W2891032444 hasRelatedWork W3120359749 @default.
• W2891032444 isParatext "false" @default.
• W2891032444 isRetracted "false" @default.
• W2891032444 magId "2891032444" @default.
• W2891032444 workType "article" @default.