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- W2891073454 abstract "To determine the prevalence of carotid sinus hypersensitivity (CSH) and define heart rate (HR) and blood pressure (BP) responses to carotid sinus massage (CSM) in (a) an unselected community sample of older people and (b) a sub-sample with no prior history of syncope, dizziness or falls. One thousand subjects were randomly sampled from a general practice database of 1517 patients over 65 years and stratified for age and gender. Consenting participants underwent detailed clinical assessment prior to supine and upright carotid sinus massage CSM with continuous heart rate and phasic blood pressure monitoring. CSH was defined as asystole in excess of 3 seconds and / or a drop in SBP of greater than 50mmHg. 272 participants had CSM. CSH was present in 107 (39%); 27% had asystole >3 seconds during CSM; 16% had symptoms (including syncope) with CSH. Previous history of syncope falls or dizziness was not predictive of CSH. Age (OR 1.05 95%CI 1.00, 1.09) and male sex (OR 1.71; 95%CI 1.04, 2.82) were the only independent predictors of CSH. In a previously asymptomatic sub-sample of 80 participants, CSH was present in 28 (35%). The 95th percentile for response was 7.3 seconds' asystole and 77mmHg drop in systolic blood pressure (7.1 seconds and 74mmHg when supine; 5.6 seconds and 76mmHg when erect). CSH is common in older persons, even those with no prior history of syncope, dizziness, or falls. Derived normal thresholds for heart rate and blood pressure responses are larger than previously reported in symptomatic groups. When present, CSH cannot be assumed to be the attributable cause in those presenting with syncope and further work is required to determine the factors which transform CSH into a symptomatic state." @default.
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- W2891073454 date "2005-10-01" @default.
- W2891073454 modified "2023-09-26" @default.
- W2891073454 title "Carotid Sinus Hypersensitivity in the Community" @default.
- W2891073454 doi "https://doi.org/10.1016/j.eupc.2005.08.012" @default.
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