FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891115480> ?p ?o ?g. }

• W2891115480 endingPage "22995" @default.
• W2891115480 startingPage "22985" @default.
• W2891115480 abstract "Supported lipid bilayers on solid surfaces have promising potential for diverse applications, such as separation processes, biosensors, drug delivery, and more. However, the self-assembly of supported lipid bilayers via vesicle fusion—the commonly used preparation method for these lipid bilayers—is not fully understood. It is often found that lipid bilayers are patchy or exhibit holes/defects, which may hinder their applicability. Moreover, it is not fully understood whether these holes are transient, kinetically trapped, or thermodynamically stable (long-lasting). Here, we derived equations to quantitatively describe the mechanism of vesicle fusion on atomically smooth hydrophilic surfaces. The derived equations determine whether defectless lipid bilayers are thermodynamically stable/favorable and qualitatively predict the self-assembly rate. It is shown that vesicle fusion is governed by van der Waals and double layer interactions, as well as undulation repulsion between the lipid bilayers and the solid surface. Utilizing various experimental techniques, we confirmed the equation predictions by studying the self-assembly of lipid bilayers on silicon wafers using lipid mixtures that exhibited different electric potentials. Furthermore, we found that cholesterol increases the lipid bilayer resistivity—a crucial parameter for several applications—and the rate of self-assembly, by decreasing both the dielectric constant of the lipid bilayer and the undulation repulsion between the lipid bilayers and the solid surface. The derived equations can be used as quantitative guidelines for designing supported lipid structures on the surface, such as a layer of intact lipid vesicles, patchy or defectless lipid bilayers." @default.
• W2891115480 created "2018-09-27" @default.
• W2891115480 creator A5046843114 @default.
• W2891115480 creator A5052161040 @default.
• W2891115480 creator A5062875445 @default.
• W2891115480 creator A5067995255 @default.
• W2891115480 creator A5061409679 @default.
• W2891115480 date "2018-09-17" @default.
• W2891115480 modified "2023-10-03" @default.
• W2891115480 title "Quantitative Description of the Vesicle Fusion Mechanism on Solid Surfaces and the Role of Cholesterol" @default.
• W2891115480 cites W1827188254 @default.
• W2891115480 cites W1973258944 @default.
• W2891115480 cites W1980366490 @default.
• W2891115480 cites W1981008452 @default.
• W2891115480 cites W1981853493 @default.
• W2891115480 cites W2002606670 @default.
• W2891115480 cites W2010538630 @default.
• W2891115480 cites W2016473952 @default.
• W2891115480 cites W2017513009 @default.
• W2891115480 cites W2025108044 @default.
• W2891115480 cites W2043544498 @default.
• W2891115480 cites W2048191546 @default.
• W2891115480 cites W2052441727 @default.
• W2891115480 cites W2056403464 @default.
• W2891115480 cites W2059705643 @default.
• W2891115480 cites W2059918628 @default.
• W2891115480 cites W2061718144 @default.
• W2891115480 cites W2065790254 @default.
• W2891115480 cites W2067526822 @default.
• W2891115480 cites W2069832711 @default.
• W2891115480 cites W2070999775 @default.
• W2891115480 cites W2071475257 @default.
• W2891115480 cites W2076601910 @default.
• W2891115480 cites W2079250598 @default.
• W2891115480 cites W2087485733 @default.
• W2891115480 cites W2093203118 @default.
• W2891115480 cites W2097065797 @default.
• W2891115480 cites W2103161015 @default.
• W2891115480 cites W2104776612 @default.
• W2891115480 cites W2106372026 @default.
• W2891115480 cites W2113989429 @default.
• W2891115480 cites W2115040835 @default.
• W2891115480 cites W2122486657 @default.
• W2891115480 cites W2125313703 @default.
• W2891115480 cites W2131295615 @default.
• W2891115480 cites W2131621038 @default.
• W2891115480 cites W2150379629 @default.
• W2891115480 cites W2170236602 @default.
• W2891115480 cites W2273501397 @default.
• W2891115480 cites W2314193143 @default.
• W2891115480 cites W2315617191 @default.
• W2891115480 cites W2319666796 @default.
• W2891115480 cites W2321293589 @default.
• W2891115480 cites W2335672459 @default.
• W2891115480 cites W2403761724 @default.
• W2891115480 cites W2504853149 @default.
• W2891115480 cites W2508863355 @default.
• W2891115480 cites W2547299595 @default.
• W2891115480 cites W2744820673 @default.
• W2891115480 cites W2749245867 @default.
• W2891115480 cites W2759153910 @default.
• W2891115480 cites W2768145561 @default.
• W2891115480 cites W2779784082 @default.
• W2891115480 doi "https://doi.org/10.1021/acs.jpcc.8b06566" @default.
• W2891115480 hasPublicationYear "2018" @default.
• W2891115480 type Work @default.
• W2891115480 sameAs 2891115480 @default.
• W2891115480 citedByCount "11" @default.
• W2891115480 countsByYear W28911154802019 @default.
• W2891115480 countsByYear W28911154802020 @default.
• W2891115480 countsByYear W28911154802021 @default.
• W2891115480 countsByYear W28911154802022 @default.
• W2891115480 countsByYear W28911154802023 @default.
• W2891115480 crossrefType "journal-article" @default.
• W2891115480 hasAuthorship W2891115480A5046843114 @default.
• W2891115480 hasAuthorship W2891115480A5052161040 @default.
• W2891115480 hasAuthorship W2891115480A5061409679 @default.
• W2891115480 hasAuthorship W2891115480A5062875445 @default.
• W2891115480 hasAuthorship W2891115480A5067995255 @default.
• W2891115480 hasConcept C103038307 @default.
• W2891115480 hasConcept C12554922 @default.
• W2891115480 hasConcept C130316041 @default.
• W2891115480 hasConcept C138885662 @default.
• W2891115480 hasConcept C148785051 @default.
• W2891115480 hasConcept C158525013 @default.
• W2891115480 hasConcept C159467904 @default.
• W2891115480 hasConcept C171250308 @default.
• W2891115480 hasConcept C185592680 @default.
• W2891115480 hasConcept C192157962 @default.
• W2891115480 hasConcept C192562407 @default.
• W2891115480 hasConcept C196330066 @default.
• W2891115480 hasConcept C39944091 @default.
• W2891115480 hasConcept C41625074 @default.
• W2891115480 hasConcept C41895202 @default.
• W2891115480 hasConcept C55493867 @default.
• W2891115480 hasConcept C76564549 @default.
• W2891115480 hasConcept C85145957 @default.
• W2891115480 hasConcept C86803240 @default.

• next