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- W2891135984 abstract "The ubiquity of horizontal gene transfer in the living world, especially among prokaryotes, raises interesting and important scientific questions regarding its effects on the human holobiont i.e., the human and its resident bacterial communities considered together as a unit of selection. Specifically, it would be interesting to determine how particular gene transfer events have influenced holobiont phenotypes in particular ecological niches and, conversely, how specific holobiont phenotypes have influenced gene transfer events. In this synthetic review, we list some notable and recent discoveries of horizontal gene transfer among the prokaryotic component of the human microbiota, and analyze their potential impact on the holobiont from an ecological-evolutionary viewpoint. Finally, the human-Helicobacter pylori association is presented as an illustration of these considerations, followed by a delineation of unresolved questions and avenues for future research." @default.
- W2891135984 created "2018-09-27" @default.
- W2891135984 creator A5021909871 @default.
- W2891135984 date "2018-09-17" @default.
- W2891135984 modified "2023-09-29" @default.
- W2891135984 title "Prokaryotic horizontal gene transfer within the human holobiont: ecological-evolutionary inferences, implications and possibilities" @default.
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