Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891156714> ?p ?o ?g. }
- W2891156714 abstract "Spontaneous unexplained preterm labor with intact membrane (sPTL-IM) remains as an unresolved challenge in obstetrics due to the complex syndromes involved during preterm birth. Two dimensional-gel electrophoresis (2D-GE) coupled with matrix-assisted laser desorption/ionization-time of flight/time of flight (MALDI TOF/TOF) mass spectrometry has become an alternative in screening for potential novel protein-based biomarkers and revealing the pathophysiology of sPTL-IM. To achieve this objective, protein extracted from fetal and maternal sides of the placenta obtained from sPTL-IM (n = 5) and the respective control (n = 10) groups were separated and compared using 2D-gel electrophoresis. MALDI-TOF/TOF mass spectrometry was utilized to identify the differentially expressed proteins between both groups, and the molecular functions of these proteins were studied. A total of 12 proteins were significantly differentiated in sPTL-IM over the control. Differentially expressed proteins were identified to have involved in structural/cytoskeletal components, immune responses, fetal and placenta development, and anticoagulation cascade. More proteins were found to be differentially expressed in the fetal side compared to the maternal side of the placenta. This postulates that the influence of sPTL-IM from fetus is greater than that of the mother. Ultimately, these results might lead to further investigations in elucidating the potential of these proteins as biomarkers and/or drug targets." @default.
- W2891156714 created "2018-09-27" @default.
- W2891156714 creator A5002560374 @default.
- W2891156714 creator A5017786560 @default.
- W2891156714 creator A5023350544 @default.
- W2891156714 creator A5032664000 @default.
- W2891156714 creator A5049411163 @default.
- W2891156714 date "2018-09-12" @default.
- W2891156714 modified "2023-09-28" @default.
- W2891156714 title "Spontaneous Unexplained Preterm Labor with Intact Membrane: Finding Protein Biomarkers through Placenta Proteome" @default.
- W2891156714 cites W1527120121 @default.
- W2891156714 cites W1580347875 @default.
- W2891156714 cites W1585536154 @default.
- W2891156714 cites W1662116527 @default.
- W2891156714 cites W1932669647 @default.
- W2891156714 cites W1970172365 @default.
- W2891156714 cites W1977112132 @default.
- W2891156714 cites W1977499446 @default.
- W2891156714 cites W1980748145 @default.
- W2891156714 cites W1983932750 @default.
- W2891156714 cites W1984970610 @default.
- W2891156714 cites W1986484438 @default.
- W2891156714 cites W1990230104 @default.
- W2891156714 cites W1994423579 @default.
- W2891156714 cites W1995865956 @default.
- W2891156714 cites W1995936718 @default.
- W2891156714 cites W1998551731 @default.
- W2891156714 cites W1999431237 @default.
- W2891156714 cites W2003364585 @default.
- W2891156714 cites W2008029664 @default.
- W2891156714 cites W2014246135 @default.
- W2891156714 cites W2015982738 @default.
- W2891156714 cites W2016535638 @default.
- W2891156714 cites W2018701944 @default.
- W2891156714 cites W2023655975 @default.
- W2891156714 cites W2027457818 @default.
- W2891156714 cites W2044853699 @default.
- W2891156714 cites W2057626412 @default.
- W2891156714 cites W2063804160 @default.
- W2891156714 cites W2074825188 @default.
- W2891156714 cites W2076891726 @default.
- W2891156714 cites W2077666808 @default.
- W2891156714 cites W2080006852 @default.
- W2891156714 cites W2080078172 @default.
- W2891156714 cites W2090390052 @default.
- W2891156714 cites W2091356803 @default.
- W2891156714 cites W2099070400 @default.
- W2891156714 cites W2106104034 @default.
- W2891156714 cites W2107392145 @default.
- W2891156714 cites W2113049830 @default.
- W2891156714 cites W2116427249 @default.
- W2891156714 cites W2121105894 @default.
- W2891156714 cites W2126048177 @default.
- W2891156714 cites W2127204699 @default.
- W2891156714 cites W2137105211 @default.
- W2891156714 cites W2143512531 @default.
- W2891156714 cites W2150205603 @default.
- W2891156714 cites W2151868528 @default.
- W2891156714 cites W2151970077 @default.
- W2891156714 cites W2153888291 @default.
- W2891156714 cites W2155556701 @default.
- W2891156714 cites W2157520876 @default.
- W2891156714 cites W2157790448 @default.
- W2891156714 cites W2158705254 @default.
- W2891156714 cites W2256869154 @default.
- W2891156714 cites W2314651877 @default.
- W2891156714 cites W2381481213 @default.
- W2891156714 cites W2481152421 @default.
- W2891156714 cites W2561254174 @default.
- W2891156714 cites W2564918254 @default.
- W2891156714 cites W2611931704 @default.
- W2891156714 cites W4238146583 @default.
- W2891156714 doi "https://doi.org/10.5772/intechopen.74925" @default.
- W2891156714 hasPublicationYear "2018" @default.
- W2891156714 type Work @default.
- W2891156714 sameAs 2891156714 @default.
- W2891156714 citedByCount "0" @default.
- W2891156714 crossrefType "book-chapter" @default.
- W2891156714 hasAuthorship W2891156714A5002560374 @default.
- W2891156714 hasAuthorship W2891156714A5017786560 @default.
- W2891156714 hasAuthorship W2891156714A5023350544 @default.
- W2891156714 hasAuthorship W2891156714A5032664000 @default.
- W2891156714 hasAuthorship W2891156714A5049411163 @default.
- W2891156714 hasBestOaLocation W28911567141 @default.
- W2891156714 hasConcept C104317684 @default.
- W2891156714 hasConcept C104397665 @default.
- W2891156714 hasConcept C116084860 @default.
- W2891156714 hasConcept C16685009 @default.
- W2891156714 hasConcept C172680121 @default.
- W2891156714 hasConcept C2776953305 @default.
- W2891156714 hasConcept C2779234561 @default.
- W2891156714 hasConcept C2780899479 @default.
- W2891156714 hasConcept C46111723 @default.
- W2891156714 hasConcept C47793336 @default.
- W2891156714 hasConcept C54355233 @default.
- W2891156714 hasConcept C55493867 @default.
- W2891156714 hasConcept C60644358 @default.
- W2891156714 hasConcept C71924100 @default.
- W2891156714 hasConcept C86803240 @default.
- W2891156714 hasConceptScore W2891156714C104317684 @default.