Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891195877> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2891195877 endingPage "128" @default.
- W2891195877 startingPage "128" @default.
- W2891195877 abstract "Abstract Background Definitive chemoradiotherapy (dCRT) is one of the treatment strategies for patients with locally advanced esophageal squamous cell carcinoma (LA-ESCC). In this report, we investigated the timing, pattern of recurrence, and prognosis in patients with LA-ESCC who achieved clinical complete response (cCR) following dCRT. Methods dCRT was performed for 71 patients with LA-ESCC from April 2006 and December 2017. We retrospectively examined the clinical records of 27 patients (38%) with ESCC who achieved cCR following dCRT assessed by the Response Evaluation Criteria in Solid Tumors (RECIST). These patients were classified into two groups: 19 patients (Group A) who did not recognize recurrence thereafter and 8 cases (Group B) who were confirmed to have recurred until Deccember 2017. Clinicopathological features and clinical course for two groups were examined. Results Clinical stages before treatment were cT1/2/3/4 = 7/3/6/3 cases, cN0/1/2/3 = 8/3/6/2, cM0/1 = 18/1 and cStage I/II/III/IV = 6/4/6/3 in Group A, and cT1/2/3/4 = 1/3/2/2, cN0/1/2/3 = 1/2/4/1, cM0/1 = 8/0, cStage I/II/III/IV = 1/0/5/2 in Group B, respectively. Patients in Group B had more advanced cases than Group A. In group A, 16 out of 19 patients (84%) are still alive without recurrence and 3 have died because of hypopharyngial cancer, lung cancer, and senility, respectively. Double cancers were confirmed in 12 patients (63%) including 6 head and neck cancers. In Group B, the recurrences were confirmed at 7–26 months (Median: 12.5M) from the diagnosis of cCR. Six out of 8 patients (6/8:75%) had the recurrence of mediastinal lymph nodes. In Group B, 6 out of 8 cases (75%) confirmed death, and the period from recurrence to death was 5–18 months (median: 9.5M). Conclusion After cCR was obtained by dCRT, recurrence was observed in 8/27 cases (29.6%) in about 13 months. In patients with recurrence, 75% of patients had mediastinal lymph node recurrence and had poor prognosis of about 10 months. Also in patients without recurrence, double cancers were observed in 12/19 cases, suggesting the importance of surveillance for the purpose of 2nd primary cancer screening. Disclosure All authors have declared no conflicts of interest." @default.
- W2891195877 created "2018-09-27" @default.
- W2891195877 creator A5006205544 @default.
- W2891195877 creator A5031920931 @default.
- W2891195877 creator A5033360182 @default.
- W2891195877 creator A5045062463 @default.
- W2891195877 creator A5045640674 @default.
- W2891195877 creator A5051765795 @default.
- W2891195877 creator A5057869081 @default.
- W2891195877 creator A5067567361 @default.
- W2891195877 creator A5076533221 @default.
- W2891195877 creator A5080639400 @default.
- W2891195877 creator A5084247658 @default.
- W2891195877 creator A5087015872 @default.
- W2891195877 date "2018-09-01" @default.
- W2891195877 modified "2023-09-25" @default.
- W2891195877 title "PS02.030: CLINICAL COURSE OF PATIENTS WITH COMPLETE RESPONSE BY CHEMORADIOTHERAPY FOR LOCALLY ADVANCED ESOPHAGIEAL CANCER" @default.
- W2891195877 doi "https://doi.org/10.1093/dote/doy089.ps02.030" @default.
- W2891195877 hasPublicationYear "2018" @default.
- W2891195877 type Work @default.
- W2891195877 sameAs 2891195877 @default.
- W2891195877 citedByCount "0" @default.
- W2891195877 crossrefType "journal-article" @default.
- W2891195877 hasAuthorship W2891195877A5006205544 @default.
- W2891195877 hasAuthorship W2891195877A5031920931 @default.
- W2891195877 hasAuthorship W2891195877A5033360182 @default.
- W2891195877 hasAuthorship W2891195877A5045062463 @default.
- W2891195877 hasAuthorship W2891195877A5045640674 @default.
- W2891195877 hasAuthorship W2891195877A5051765795 @default.
- W2891195877 hasAuthorship W2891195877A5057869081 @default.
- W2891195877 hasAuthorship W2891195877A5067567361 @default.
- W2891195877 hasAuthorship W2891195877A5076533221 @default.
- W2891195877 hasAuthorship W2891195877A5080639400 @default.
- W2891195877 hasAuthorship W2891195877A5084247658 @default.
- W2891195877 hasAuthorship W2891195877A5087015872 @default.
- W2891195877 hasConcept C121608353 @default.
- W2891195877 hasConcept C126322002 @default.
- W2891195877 hasConcept C143998085 @default.
- W2891195877 hasConcept C2776256026 @default.
- W2891195877 hasConcept C2776530083 @default.
- W2891195877 hasConcept C2776694085 @default.
- W2891195877 hasConcept C2778424827 @default.
- W2891195877 hasConcept C2779742542 @default.
- W2891195877 hasConcept C3019096185 @default.
- W2891195877 hasConcept C3019992690 @default.
- W2891195877 hasConcept C71924100 @default.
- W2891195877 hasConcept C90924648 @default.
- W2891195877 hasConceptScore W2891195877C121608353 @default.
- W2891195877 hasConceptScore W2891195877C126322002 @default.
- W2891195877 hasConceptScore W2891195877C143998085 @default.
- W2891195877 hasConceptScore W2891195877C2776256026 @default.
- W2891195877 hasConceptScore W2891195877C2776530083 @default.
- W2891195877 hasConceptScore W2891195877C2776694085 @default.
- W2891195877 hasConceptScore W2891195877C2778424827 @default.
- W2891195877 hasConceptScore W2891195877C2779742542 @default.
- W2891195877 hasConceptScore W2891195877C3019096185 @default.
- W2891195877 hasConceptScore W2891195877C3019992690 @default.
- W2891195877 hasConceptScore W2891195877C71924100 @default.
- W2891195877 hasConceptScore W2891195877C90924648 @default.
- W2891195877 hasIssue "Supplement_1" @default.
- W2891195877 hasLocation W28911958771 @default.
- W2891195877 hasOpenAccess W2891195877 @default.
- W2891195877 hasPrimaryLocation W28911958771 @default.
- W2891195877 hasRelatedWork W171727350 @default.
- W2891195877 hasRelatedWork W2088181646 @default.
- W2891195877 hasRelatedWork W2110300801 @default.
- W2891195877 hasRelatedWork W2168952713 @default.
- W2891195877 hasRelatedWork W2312625876 @default.
- W2891195877 hasRelatedWork W2528998616 @default.
- W2891195877 hasRelatedWork W2590076301 @default.
- W2891195877 hasRelatedWork W2616626113 @default.
- W2891195877 hasRelatedWork W3201835073 @default.
- W2891195877 hasRelatedWork W4308006065 @default.
- W2891195877 hasVolume "31" @default.
- W2891195877 isParatext "false" @default.
- W2891195877 isRetracted "false" @default.
- W2891195877 magId "2891195877" @default.
- W2891195877 workType "article" @default.