FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891217422> ?p ?o ?g. }

• W2891217422 abstract "Tonsils, lympho-epithelial tissues located at the junction of the oropharynx and nasopharynx, play a key role in surveillance, colonization, and persistence of inhaled and ingested pathogens. In pigs, the tonsils are a reservoir for numerous bacteria and viruses, including host-specific pathogens and potential zoonotic pathogens as well as commensal organisms. However, there are no in depth studies of the development of the tonsillar microbiome in pigs, or any mammal, over time. The goal of this study was to follow the development of the tonsil microbiome in healthy pigs from birth to market weight. Samples were collected using tonsil brushes from 16 piglets (4 each from 4 sows) at newborn, 1, 2, 3 and 4 weeks of age, and from 8 of those piglets at 6, 8, 10, 12, 16 and 19 weeks of age. Bacterial DNA was isolated from each sample and 16S rDNA genes were amplified and sequenced. Sequence analysis showed that members of the Streptococcaceae, Pasteurellaceae and Moraxellaceae were present at all time points and represent the three most abundant families identified. Other community members appeared transiently or increased or decreased significantly with disruption events or stress. We observed four significant shifts in the tonsil community that coincided with well-defined disruption events: weaning plus addition of Carbadox plus movement to the nursery at week 3, removal of Carbadox and addition of Tylan at week 5, removal of Tylan and habitat change at week 9, and habitat change at week 16. Weaning triggered a bloom of Streptococcaeae and decrease of Moraxellaceae. The shift from Carbadox to Tylan led to reduction in Proteobacteria and Streptococcaceae but an increase in other Firmicutes, accompanied by a dramatic increase in community richness. Cessation of Tylan coincided with a return to a less rich community, and a bloom in Clostridiales. The final shift in habitat was accompanied by a decrease in Clostridiales and increase in Proteobacteria. The tonsillar microbiome of older pigs resembled the previously described mature core tonsillar microbiome. This study demonstrates a temporal succession in the development of the pig tonsillar microbiome, and significant community shifts that correlate with disruption events." @default.
• W2891217422 created "2018-09-27" @default.
• W2891217422 creator A5005524285 @default.
• W2891217422 creator A5009099603 @default.
• W2891217422 creator A5021939882 @default.
• W2891217422 creator A5048304520 @default.
• W2891217422 creator A5063801254 @default.
• W2891217422 date "2018-09-19" @default.
• W2891217422 modified "2023-10-12" @default.
• W2891217422 title "Development of the Tonsil Microbiome in Pigs and Effects of Stress on the Microbiome" @default.
• W2891217422 cites W101072784 @default.
• W2891217422 cites W1828784438 @default.
• W2891217422 cites W1926318014 @default.
• W2891217422 cites W1970833521 @default.
• W2891217422 cites W1975261137 @default.
• W2891217422 cites W1979702887 @default.
• W2891217422 cites W1981741918 @default.
• W2891217422 cites W1983516740 @default.
• W2891217422 cites W2005983361 @default.
• W2891217422 cites W2011288206 @default.
• W2891217422 cites W2015129154 @default.
• W2891217422 cites W2023190915 @default.
• W2891217422 cites W2027467762 @default.
• W2891217422 cites W2034285706 @default.
• W2891217422 cites W2037592488 @default.
• W2891217422 cites W2052969143 @default.
• W2891217422 cites W2059022658 @default.
• W2891217422 cites W2063295309 @default.
• W2891217422 cites W2077651352 @default.
• W2891217422 cites W2080283023 @default.
• W2891217422 cites W2083537767 @default.
• W2891217422 cites W2095566926 @default.
• W2891217422 cites W2096205027 @default.
• W2891217422 cites W2099540110 @default.
• W2891217422 cites W2108498631 @default.
• W2891217422 cites W2108718991 @default.
• W2891217422 cites W2117457769 @default.
• W2891217422 cites W2120083902 @default.
• W2891217422 cites W2121392435 @default.
• W2891217422 cites W2127634163 @default.
• W2891217422 cites W2130343619 @default.
• W2891217422 cites W2134830426 @default.
• W2891217422 cites W2138007699 @default.
• W2891217422 cites W2139672978 @default.
• W2891217422 cites W2139884694 @default.
• W2891217422 cites W2150018639 @default.
• W2891217422 cites W2154465191 @default.
• W2891217422 cites W2154919362 @default.
• W2891217422 cites W2155367962 @default.
• W2891217422 cites W2158463067 @default.
• W2891217422 cites W2158907666 @default.
• W2891217422 cites W2166562121 @default.
• W2891217422 cites W2170196186 @default.
• W2891217422 cites W2235109766 @default.
• W2891217422 cites W2424275162 @default.
• W2891217422 cites W2523457784 @default.
• W2891217422 cites W2562882294 @default.
• W2891217422 cites W2607437241 @default.
• W2891217422 cites W2804821005 @default.
• W2891217422 cites W4239679757 @default.
• W2891217422 doi "https://doi.org/10.3389/fvets.2018.00220" @default.
• W2891217422 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6156429" @default.
• W2891217422 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30283792" @default.
• W2891217422 hasPublicationYear "2018" @default.
• W2891217422 type Work @default.
• W2891217422 sameAs 2891217422 @default.
• W2891217422 citedByCount "16" @default.
• W2891217422 countsByYear W28912174222019 @default.
• W2891217422 countsByYear W28912174222020 @default.
• W2891217422 countsByYear W28912174222021 @default.
• W2891217422 countsByYear W28912174222022 @default.
• W2891217422 countsByYear W28912174222023 @default.
• W2891217422 crossrefType "journal-article" @default.
• W2891217422 hasAuthorship W2891217422A5005524285 @default.
• W2891217422 hasAuthorship W2891217422A5009099603 @default.
• W2891217422 hasAuthorship W2891217422A5021939882 @default.
• W2891217422 hasAuthorship W2891217422A5048304520 @default.
• W2891217422 hasAuthorship W2891217422A5063801254 @default.
• W2891217422 hasBestOaLocation W28912174221 @default.
• W2891217422 hasConcept C140793950 @default.
• W2891217422 hasConcept C143121216 @default.
• W2891217422 hasConcept C203014093 @default.
• W2891217422 hasConcept C2777695942 @default.
• W2891217422 hasConcept C2779419017 @default.
• W2891217422 hasConcept C2779676784 @default.
• W2891217422 hasConcept C2780655333 @default.
• W2891217422 hasConcept C2908643440 @default.
• W2891217422 hasConcept C42062724 @default.
• W2891217422 hasConcept C523546767 @default.
• W2891217422 hasConcept C54355233 @default.
• W2891217422 hasConcept C86803240 @default.
• W2891217422 hasConcept C89423630 @default.
• W2891217422 hasConcept C90856448 @default.
• W2891217422 hasConceptScore W2891217422C140793950 @default.
• W2891217422 hasConceptScore W2891217422C143121216 @default.
• W2891217422 hasConceptScore W2891217422C203014093 @default.
• W2891217422 hasConceptScore W2891217422C2777695942 @default.
• W2891217422 hasConceptScore W2891217422C2779419017 @default.
• W2891217422 hasConceptScore W2891217422C2779676784 @default.
• W2891217422 hasConceptScore W2891217422C2780655333 @default.

• next