FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891237400> ?p ?o ?g. }

• W2891237400 endingPage "1886" @default.
• W2891237400 startingPage "1876" @default.
• W2891237400 abstract "The glymphatic system is a newly identified waste clearance pathway in brain discovered and investigated predominately using in vivo two-photon confocal microscopy. Magnetic resonance imaging (MRI), in contrast to two-photon confocal microscopy, provides dynamic and real-time pictures of the glymphatic system in whole brain. We employ MRI to investigate the response of the glymphatic system to the rate of infusion of Gd-DTPA (magnevist). Wistar rats were subjected to a surgery of inserting a tube into the cisterna magna for infusion during MRI. Three infusion rates were chosen for 20 min infusions of diluted magnevist into the cerebrospinal fluid (CSF) of rat brain. Glymphatic response was imaged using dynamic MRI 3D measurement for 5 hr. Robust correlations were found in all ventricles between the peak intensities of image enhancement and infusion rates, with additional correlations between the peak times of MRI image enhancement and infusion rates in the fourth ventricle. An infusion rate of 2.92 μL/min induced an evident accumulation of tracer in the fourth ventricle near the cisterna magna. In hippocampal tissue, image enhancements exhibited low correlation with the infusion rates. However, an infusion rate of 1.67 μL/min provided a high image enhancement, but less tracer accumulation near the cisterna magna. Contrast-enhanced MRI provides a suitable tool for investigating image contrast infusion rate response of the glymphatic system in rat brain. Considering both T1 and T2 * effects in response to the infused magnevist into CSF, the infusion rate of 1.67 μL/min appears suitable for MRI study of the glymphatic system in rat." @default.
• W2891237400 created "2018-09-27" @default.
• W2891237400 creator A5000323703 @default.
• W2891237400 creator A5003375036 @default.
• W2891237400 creator A5005508444 @default.
• W2891237400 creator A5015985782 @default.
• W2891237400 creator A5043844658 @default.
• W2891237400 creator A5045152683 @default.
• W2891237400 creator A5066716873 @default.
• W2891237400 creator A5067578492 @default.
• W2891237400 date "2018-09-11" @default.
• W2891237400 modified "2023-10-14" @default.
• W2891237400 title "MRI investigation of glymphatic responses to Gd-DTPA infusion rates" @default.
• W2891237400 cites W1588685142 @default.
• W2891237400 cites W1929045386 @default.
• W2891237400 cites W1932367580 @default.
• W2891237400 cites W1991348431 @default.
• W2891237400 cites W2015800692 @default.
• W2891237400 cites W2021493191 @default.
• W2891237400 cites W2028623620 @default.
• W2891237400 cites W2032220418 @default.
• W2891237400 cites W2042427055 @default.
• W2891237400 cites W2060279158 @default.
• W2891237400 cites W2081061369 @default.
• W2891237400 cites W2094785614 @default.
• W2891237400 cites W2100314515 @default.
• W2891237400 cites W2106493886 @default.
• W2891237400 cites W2112634066 @default.
• W2891237400 cites W2127716652 @default.
• W2891237400 cites W2142067181 @default.
• W2891237400 cites W2157256907 @default.
• W2891237400 cites W2163225965 @default.
• W2891237400 cites W2167183660 @default.
• W2891237400 cites W2414014505 @default.
• W2891237400 cites W2425370520 @default.
• W2891237400 cites W2437502300 @default.
• W2891237400 cites W2508310112 @default.
• W2891237400 cites W2588487507 @default.
• W2891237400 cites W2625314800 @default.
• W2891237400 cites W2750130602 @default.
• W2891237400 cites W2751474624 @default.
• W2891237400 cites W2760815599 @default.
• W2891237400 cites W2766060569 @default.
• W2891237400 doi "https://doi.org/10.1002/jnr.24325" @default.
• W2891237400 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6186187" @default.
• W2891237400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30272825" @default.
• W2891237400 hasPublicationYear "2018" @default.
• W2891237400 type Work @default.
• W2891237400 sameAs 2891237400 @default.
• W2891237400 citedByCount "22" @default.
• W2891237400 countsByYear W28912374002019 @default.
• W2891237400 countsByYear W28912374002020 @default.
• W2891237400 countsByYear W28912374002021 @default.
• W2891237400 countsByYear W28912374002022 @default.
• W2891237400 countsByYear W28912374002023 @default.
• W2891237400 crossrefType "journal-article" @default.
• W2891237400 hasAuthorship W2891237400A5000323703 @default.
• W2891237400 hasAuthorship W2891237400A5003375036 @default.
• W2891237400 hasAuthorship W2891237400A5005508444 @default.
• W2891237400 hasAuthorship W2891237400A5015985782 @default.
• W2891237400 hasAuthorship W2891237400A5043844658 @default.
• W2891237400 hasAuthorship W2891237400A5045152683 @default.
• W2891237400 hasAuthorship W2891237400A5066716873 @default.
• W2891237400 hasAuthorship W2891237400A5067578492 @default.
• W2891237400 hasBestOaLocation W28912374001 @default.
• W2891237400 hasConcept C101054994 @default.
• W2891237400 hasConcept C121332964 @default.
• W2891237400 hasConcept C142724271 @default.
• W2891237400 hasConcept C2779651940 @default.
• W2891237400 hasConcept C2989005 @default.
• W2891237400 hasConcept C46141821 @default.
• W2891237400 hasConcept C71924100 @default.
• W2891237400 hasConceptScore W2891237400C101054994 @default.
• W2891237400 hasConceptScore W2891237400C121332964 @default.
• W2891237400 hasConceptScore W2891237400C142724271 @default.
• W2891237400 hasConceptScore W2891237400C2779651940 @default.
• W2891237400 hasConceptScore W2891237400C2989005 @default.
• W2891237400 hasConceptScore W2891237400C46141821 @default.
• W2891237400 hasConceptScore W2891237400C71924100 @default.
• W2891237400 hasFunder F4320332161 @default.
• W2891237400 hasIssue "12" @default.
• W2891237400 hasLocation W28912374001 @default.
• W2891237400 hasLocation W28912374002 @default.
• W2891237400 hasLocation W28912374003 @default.
• W2891237400 hasOpenAccess W2891237400 @default.
• W2891237400 hasPrimaryLocation W28912374001 @default.
• W2891237400 hasRelatedWork W2095392742 @default.
• W2891237400 hasRelatedWork W2117672931 @default.
• W2891237400 hasRelatedWork W2185080621 @default.
• W2891237400 hasRelatedWork W2224907970 @default.
• W2891237400 hasRelatedWork W2609851299 @default.
• W2891237400 hasRelatedWork W2748952813 @default.
• W2891237400 hasRelatedWork W2783331044 @default.
• W2891237400 hasRelatedWork W2899084033 @default.
• W2891237400 hasRelatedWork W3030043941 @default.
• W2891237400 hasRelatedWork W3032375762 @default.
• W2891237400 hasVolume "96" @default.
• W2891237400 isParatext "false" @default.

• next