FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891254780> ?p ?o ?g. }

• W2891254780 endingPage "90" @default.
• W2891254780 startingPage "84" @default.
• W2891254780 abstract "Objective: Antipsychotic use in older patients is associated with many adverse effects, including tardive dyskinesia and extrapyramidal symptoms, which, in turn, increase the risk of falling. Antipsychotics are also associated with metabolic syndrome and cognitive impairment in older patients. Integrated care pathways (ICPs) are designed to manage specific conditions using standardized assessments and measurement-based interventions. This study aims to compare the use of recommended tools to monitor for adverse effects associated with antipsychotics in older patients managed within an ICP and those managed under usual care conditions—i.e., treatment as usual (TAU). Methods: We reviewed and compared the health records of 100 older patients enrolled in an ICP for late-life schizophrenia with those of 100 older patients treated with antipsychotics under TAU conditions. Results: Monitoring rates were significantly higher in the ICP group than in the TAU group for all assessments: extrapyramidal symptoms (94% versus 5%), metabolic disturbances (91% versus 25%), fall risk (82% versus 35%), and cognitive impairment (72% versus 28%). Rates of antipsychotic polypharmacy were also six times higher in the TAU group. Conclusion: Older patients with schizophrenia treated with antipsychotics within an ICP experience higher rates of monitoring and less psychotropic polypharmacy than older patients treated with antipsychotics under TAU conditions. These findings suggest that an ICP can improve the quality of antipsychotic pharmacotherapy in older patients and thus possibly its effectiveness. This needs to be confirmed by a randomized controlled trial. Objective: Antipsychotic use in older patients is associated with many adverse effects, including tardive dyskinesia and extrapyramidal symptoms, which, in turn, increase the risk of falling. Antipsychotics are also associated with metabolic syndrome and cognitive impairment in older patients. Integrated care pathways (ICPs) are designed to manage specific conditions using standardized assessments and measurement-based interventions. This study aims to compare the use of recommended tools to monitor for adverse effects associated with antipsychotics in older patients managed within an ICP and those managed under usual care conditions—i.e., treatment as usual (TAU). Methods: We reviewed and compared the health records of 100 older patients enrolled in an ICP for late-life schizophrenia with those of 100 older patients treated with antipsychotics under TAU conditions. Results: Monitoring rates were significantly higher in the ICP group than in the TAU group for all assessments: extrapyramidal symptoms (94% versus 5%), metabolic disturbances (91% versus 25%), fall risk (82% versus 35%), and cognitive impairment (72% versus 28%). Rates of antipsychotic polypharmacy were also six times higher in the TAU group. Conclusion: Older patients with schizophrenia treated with antipsychotics within an ICP experience higher rates of monitoring and less psychotropic polypharmacy than older patients treated with antipsychotics under TAU conditions. These findings suggest that an ICP can improve the quality of antipsychotic pharmacotherapy in older patients and thus possibly its effectiveness. This needs to be confirmed by a randomized controlled trial." @default.
• W2891254780 created "2018-09-27" @default.
• W2891254780 creator A5017168531 @default.
• W2891254780 creator A5019562259 @default.
• W2891254780 creator A5033504388 @default.
• W2891254780 creator A5064979886 @default.
• W2891254780 creator A5073038475 @default.
• W2891254780 date "2019-01-01" @default.
• W2891254780 modified "2023-09-25" @default.
• W2891254780 title "Using an Integrated Care Pathway for Late-Life Schizophrenia Improves Monitoring of Adverse Effects of Antipsychotics and Reduces Antipsychotic Polypharmacy" @default.
• W2891254780 cites W1765464910 @default.
• W2891254780 cites W1986011584 @default.
• W2891254780 cites W1995307465 @default.
• W2891254780 cites W1997695932 @default.
• W2891254780 cites W1998076638 @default.
• W2891254780 cites W1999689270 @default.
• W2891254780 cites W2046353273 @default.
• W2891254780 cites W2084556419 @default.
• W2891254780 cites W2105915837 @default.
• W2891254780 cites W2116251861 @default.
• W2891254780 cites W2144590229 @default.
• W2891254780 cites W2157959378 @default.
• W2891254780 cites W2161358611 @default.
• W2891254780 cites W2165379748 @default.
• W2891254780 cites W2165758561 @default.
• W2891254780 cites W2171151223 @default.
• W2891254780 cites W2231488402 @default.
• W2891254780 cites W2242500082 @default.
• W2891254780 cites W2752211098 @default.
• W2891254780 cites W2763920048 @default.
• W2891254780 cites W2763925245 @default.
• W2891254780 cites W2792740246 @default.
• W2891254780 cites W3023707133 @default.
• W2891254780 cites W4248762040 @default.
• W2891254780 cites W4294058577 @default.
• W2891254780 cites W93996663 @default.
• W2891254780 doi "https://doi.org/10.1016/j.jagp.2018.09.003" @default.
• W2891254780 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30396766" @default.
• W2891254780 hasPublicationYear "2019" @default.
• W2891254780 type Work @default.
• W2891254780 sameAs 2891254780 @default.
• W2891254780 citedByCount "6" @default.
• W2891254780 countsByYear W28912547802021 @default.
• W2891254780 countsByYear W28912547802022 @default.
• W2891254780 crossrefType "journal-article" @default.
• W2891254780 hasAuthorship W2891254780A5017168531 @default.
• W2891254780 hasAuthorship W2891254780A5019562259 @default.
• W2891254780 hasAuthorship W2891254780A5033504388 @default.
• W2891254780 hasAuthorship W2891254780A5064979886 @default.
• W2891254780 hasAuthorship W2891254780A5073038475 @default.
• W2891254780 hasConcept C118552586 @default.
• W2891254780 hasConcept C126322002 @default.
• W2891254780 hasConcept C159110408 @default.
• W2891254780 hasConcept C187212893 @default.
• W2891254780 hasConcept C197934379 @default.
• W2891254780 hasConcept C2776412080 @default.
• W2891254780 hasConcept C2779134260 @default.
• W2891254780 hasConcept C2779158372 @default.
• W2891254780 hasConcept C2779734285 @default.
• W2891254780 hasConcept C2779951463 @default.
• W2891254780 hasConcept C2780405171 @default.
• W2891254780 hasConcept C2780494398 @default.
• W2891254780 hasConcept C2780616385 @default.
• W2891254780 hasConcept C2780864610 @default.
• W2891254780 hasConcept C36434225 @default.
• W2891254780 hasConcept C71924100 @default.
• W2891254780 hasConceptScore W2891254780C118552586 @default.
• W2891254780 hasConceptScore W2891254780C126322002 @default.
• W2891254780 hasConceptScore W2891254780C159110408 @default.
• W2891254780 hasConceptScore W2891254780C187212893 @default.
• W2891254780 hasConceptScore W2891254780C197934379 @default.
• W2891254780 hasConceptScore W2891254780C2776412080 @default.
• W2891254780 hasConceptScore W2891254780C2779134260 @default.
• W2891254780 hasConceptScore W2891254780C2779158372 @default.
• W2891254780 hasConceptScore W2891254780C2779734285 @default.
• W2891254780 hasConceptScore W2891254780C2779951463 @default.
• W2891254780 hasConceptScore W2891254780C2780405171 @default.
• W2891254780 hasConceptScore W2891254780C2780494398 @default.
• W2891254780 hasConceptScore W2891254780C2780616385 @default.
• W2891254780 hasConceptScore W2891254780C2780864610 @default.
• W2891254780 hasConceptScore W2891254780C36434225 @default.
• W2891254780 hasConceptScore W2891254780C71924100 @default.
• W2891254780 hasIssue "1" @default.
• W2891254780 hasLocation W28912547801 @default.
• W2891254780 hasLocation W28912547802 @default.
• W2891254780 hasOpenAccess W2891254780 @default.
• W2891254780 hasPrimaryLocation W28912547801 @default.
• W2891254780 hasRelatedWork W141644431 @default.
• W2891254780 hasRelatedWork W1567719012 @default.
• W2891254780 hasRelatedWork W1990712459 @default.
• W2891254780 hasRelatedWork W1995128563 @default.
• W2891254780 hasRelatedWork W2016392487 @default.
• W2891254780 hasRelatedWork W2070662185 @default.
• W2891254780 hasRelatedWork W2076320623 @default.
• W2891254780 hasRelatedWork W2340061843 @default.
• W2891254780 hasRelatedWork W2398599796 @default.
• W2891254780 hasRelatedWork W2891254780 @default.
• W2891254780 hasVolume "27" @default.

• next