Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891299305> ?p ?o ?g. }
- W2891299305 abstract "Closed-loop resuscitation can improve personalization of care, decrease workload and bring expert knowledge in isolated areas. We have developed a new device to control the administration of fluid or simultaneous co-administration of fluid and norepinephrine using arterial pressure.We evaluated the performance of our prototype in a rodent model of haemorrhagic shock. After haemorrhagic shock, rats were randomized to five experimental groups: three were resuscitated with fluid and two with co-administration of fluid and norepinephrine. Among groups resuscitated with fluid, one was resuscitated by a physician and two were resuscitated according to two different closed-loop algorithms. Among groups resuscitated with fluid and norepinephrine, one was resuscitated by a physician and the other one by the closed-loop device. The precision of arterial pressure during the resuscitation period was assessed using rising time, time passed in the target area and performance error calculations.Groups resuscitated with fluid had similar performances and passed as much time in the target area of 80-90 mmHg as the manual group [manual: 76.8% (67.9-78.2), closed-loop: 64.6% (45.7-72.9) and 80.9% (59.1-85.3)]. Rats resuscitated with fluid and norepinephrine using closed-loop passed similar time in target area than manual group [closed-loop: 74.4% (58.4-84.5) vs. manual: 60.1% (46.1-72.4)] but had shorter rising time to reach target area [160 s (106-187) vs. 434 s (254-1081)] than those resuscitated by a physician. Rats resuscitated with co-administration of fluid and norepinephrine required less fluid and had less hemodilution than rats resuscitated with fluid alone. Lactate decrease was similar between groups resuscitated with fluid alone and fluid with norepinephrine.This study assessed extensively the performances of several algorithms for closed-loop resuscitation of haemorrhagic shock with fluid alone and with co-administration of fluid and norepinephrine. The performance of the closed-loop algorithms tested was similar to physician-guided treatment with considerable saving of work for the caregiver. Arterial pressure closed-loop guided algorithms can be extended to combined administration of fluid and norepinephrine." @default.
- W2891299305 created "2018-09-27" @default.
- W2891299305 creator A5002418559 @default.
- W2891299305 creator A5009935736 @default.
- W2891299305 creator A5040000226 @default.
- W2891299305 creator A5040447631 @default.
- W2891299305 creator A5042087592 @default.
- W2891299305 creator A5055297294 @default.
- W2891299305 creator A5070317004 @default.
- W2891299305 creator A5088096181 @default.
- W2891299305 date "2018-09-17" @default.
- W2891299305 modified "2023-10-18" @default.
- W2891299305 title "Performance of closed-loop resuscitation of haemorrhagic shock with fluid alone or in combination with norepinephrine: an experimental study" @default.
- W2891299305 cites W139109914 @default.
- W2891299305 cites W1630835083 @default.
- W2891299305 cites W1885078077 @default.
- W2891299305 cites W1971410089 @default.
- W2891299305 cites W1972267629 @default.
- W2891299305 cites W1979650981 @default.
- W2891299305 cites W1986855353 @default.
- W2891299305 cites W1990650554 @default.
- W2891299305 cites W1996446238 @default.
- W2891299305 cites W2001131888 @default.
- W2891299305 cites W2007254392 @default.
- W2891299305 cites W2038873307 @default.
- W2891299305 cites W2043742363 @default.
- W2891299305 cites W2062176705 @default.
- W2891299305 cites W2066521846 @default.
- W2891299305 cites W2071582480 @default.
- W2891299305 cites W2153892207 @default.
- W2891299305 cites W2178166836 @default.
- W2891299305 cites W2338438098 @default.
- W2891299305 cites W2345256390 @default.
- W2891299305 cites W2407419311 @default.
- W2891299305 cites W2568246828 @default.
- W2891299305 cites W2730416821 @default.
- W2891299305 cites W2766980868 @default.
- W2891299305 cites W88508713 @default.
- W2891299305 doi "https://doi.org/10.1186/s13613-018-0436-0" @default.
- W2891299305 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6141407" @default.
- W2891299305 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30225814" @default.
- W2891299305 hasPublicationYear "2018" @default.
- W2891299305 type Work @default.
- W2891299305 sameAs 2891299305 @default.
- W2891299305 citedByCount "27" @default.
- W2891299305 countsByYear W28912993052019 @default.
- W2891299305 countsByYear W28912993052020 @default.
- W2891299305 countsByYear W28912993052021 @default.
- W2891299305 countsByYear W28912993052022 @default.
- W2891299305 countsByYear W28912993052023 @default.
- W2891299305 crossrefType "journal-article" @default.
- W2891299305 hasAuthorship W2891299305A5002418559 @default.
- W2891299305 hasAuthorship W2891299305A5009935736 @default.
- W2891299305 hasAuthorship W2891299305A5040000226 @default.
- W2891299305 hasAuthorship W2891299305A5040447631 @default.
- W2891299305 hasAuthorship W2891299305A5042087592 @default.
- W2891299305 hasAuthorship W2891299305A5055297294 @default.
- W2891299305 hasAuthorship W2891299305A5070317004 @default.
- W2891299305 hasAuthorship W2891299305A5088096181 @default.
- W2891299305 hasBestOaLocation W28912993051 @default.
- W2891299305 hasConcept C126322002 @default.
- W2891299305 hasConcept C127413603 @default.
- W2891299305 hasConcept C133731056 @default.
- W2891299305 hasConcept C2778165595 @default.
- W2891299305 hasConcept C2778514916 @default.
- W2891299305 hasConcept C2781300812 @default.
- W2891299305 hasConcept C3019251811 @default.
- W2891299305 hasConcept C42219234 @default.
- W2891299305 hasConcept C513476851 @default.
- W2891299305 hasConcept C71924100 @default.
- W2891299305 hasConceptScore W2891299305C126322002 @default.
- W2891299305 hasConceptScore W2891299305C127413603 @default.
- W2891299305 hasConceptScore W2891299305C133731056 @default.
- W2891299305 hasConceptScore W2891299305C2778165595 @default.
- W2891299305 hasConceptScore W2891299305C2778514916 @default.
- W2891299305 hasConceptScore W2891299305C2781300812 @default.
- W2891299305 hasConceptScore W2891299305C3019251811 @default.
- W2891299305 hasConceptScore W2891299305C42219234 @default.
- W2891299305 hasConceptScore W2891299305C513476851 @default.
- W2891299305 hasConceptScore W2891299305C71924100 @default.
- W2891299305 hasIssue "1" @default.
- W2891299305 hasLocation W28912993051 @default.
- W2891299305 hasLocation W28912993052 @default.
- W2891299305 hasLocation W28912993053 @default.
- W2891299305 hasLocation W28912993054 @default.
- W2891299305 hasLocation W28912993055 @default.
- W2891299305 hasLocation W28912993056 @default.
- W2891299305 hasLocation W28912993057 @default.
- W2891299305 hasOpenAccess W2891299305 @default.
- W2891299305 hasPrimaryLocation W28912993051 @default.
- W2891299305 hasRelatedWork W1993975100 @default.
- W2891299305 hasRelatedWork W2036907831 @default.
- W2891299305 hasRelatedWork W2086754639 @default.
- W2891299305 hasRelatedWork W2087737319 @default.
- W2891299305 hasRelatedWork W2167641578 @default.
- W2891299305 hasRelatedWork W2365513417 @default.
- W2891299305 hasRelatedWork W2368125093 @default.
- W2891299305 hasRelatedWork W2372304092 @default.
- W2891299305 hasRelatedWork W2379999974 @default.
- W2891299305 hasRelatedWork W2417461381 @default.