Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891314300> ?p ?o ?g. }
- W2891314300 endingPage "1228" @default.
- W2891314300 startingPage "1222" @default.
- W2891314300 abstract "Burkholderia pseudomallei, the etiological agent of melioidosis, has been hypothesized to be endemic throughout the Caribbean, including the impoverished nation of Haiti. However, because of the protean clinical manifestations, presence of asymptomatic infections, and limited medical diagnostic capacity, the identification of active melioidosis cases remains challenging. A seroepidemiological study was conducted using a novel enzyme-linked immunosorbent assay (ELISA) to detect antibodies toward B. pseudomallei in the native population. The performance of an indirect ELISA with purified lipopolysaccharide (LPS) from B. pseudomallei was evaluated using serum collected from rhesus macaques exposed to aerosolized B. pseudomallei. After optimization, serum collected from asymptomatic population members (n = 756) was screened for polyvalent (immunoglobulin M [IgM]/ immunoglobulin G [IgG]/ immunoglobulin A) and monoclonal (IgG or IgM) immunoglobulins against B. pseudomallei LPS. The population seroprevalence was 11.5% (95% confidence interval [CI]: 9.2, 13.8) for polyvalent immunoglobulins, 9.8% (95% CI: 7.7, 11.9) for IgG, and 1.7% (95% CI: 0.8, 2.6%) for IgM. The seroprevalence was not significantly different by gender (P = 0.16), but increased significantly (P < 0.001) with age, yielding an estimated annual seroconversion rate of 1.05% (95% CI: 0.81, 1.3). The detection of both recent (IgM+) and previous (IgG+) exposure to B. pseudomallei provides serological evidence that melioidosis is endemic in Haiti." @default.
- W2891314300 created "2018-09-27" @default.
- W2891314300 creator A5010227373 @default.
- W2891314300 creator A5018324088 @default.
- W2891314300 creator A5020811677 @default.
- W2891314300 creator A5033417581 @default.
- W2891314300 creator A5042611719 @default.
- W2891314300 creator A5053214575 @default.
- W2891314300 creator A5065505722 @default.
- W2891314300 creator A5065887066 @default.
- W2891314300 creator A5081454914 @default.
- W2891314300 date "2018-11-07" @default.
- W2891314300 modified "2023-09-24" @default.
- W2891314300 title "Seroepidemiology of Burkholderia pseudomallei, Etiologic Agent of Melioidosis, in the Ouest and Sud-Est Departments of Haiti" @default.
- W2891314300 cites W1949236270 @default.
- W2891314300 cites W1967263416 @default.
- W2891314300 cites W1970600985 @default.
- W2891314300 cites W1976737249 @default.
- W2891314300 cites W2009225460 @default.
- W2891314300 cites W2021212457 @default.
- W2891314300 cites W2032299211 @default.
- W2891314300 cites W2032971911 @default.
- W2891314300 cites W2050803324 @default.
- W2891314300 cites W2051889688 @default.
- W2891314300 cites W2076553156 @default.
- W2891314300 cites W2101395506 @default.
- W2891314300 cites W2103864740 @default.
- W2891314300 cites W2104112831 @default.
- W2891314300 cites W2108986624 @default.
- W2891314300 cites W2109176599 @default.
- W2891314300 cites W2130623712 @default.
- W2891314300 cites W2142516915 @default.
- W2891314300 cites W2168065215 @default.
- W2891314300 cites W2297862035 @default.
- W2891314300 cites W2345054393 @default.
- W2891314300 cites W2407415576 @default.
- W2891314300 cites W2413464329 @default.
- W2891314300 cites W2414783923 @default.
- W2891314300 cites W2417418565 @default.
- W2891314300 cites W2423416335 @default.
- W2891314300 cites W2580471686 @default.
- W2891314300 cites W2609198670 @default.
- W2891314300 cites W2949442598 @default.
- W2891314300 cites W4211084778 @default.
- W2891314300 cites W4301792462 @default.
- W2891314300 cites W2567501567 @default.
- W2891314300 doi "https://doi.org/10.4269/ajtmh.18-0352" @default.
- W2891314300 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6221251" @default.
- W2891314300 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30226137" @default.
- W2891314300 hasPublicationYear "2018" @default.
- W2891314300 type Work @default.
- W2891314300 sameAs 2891314300 @default.
- W2891314300 citedByCount "5" @default.
- W2891314300 countsByYear W28913143002019 @default.
- W2891314300 countsByYear W28913143002020 @default.
- W2891314300 countsByYear W28913143002023 @default.
- W2891314300 crossrefType "journal-article" @default.
- W2891314300 hasAuthorship W2891314300A5010227373 @default.
- W2891314300 hasAuthorship W2891314300A5018324088 @default.
- W2891314300 hasAuthorship W2891314300A5020811677 @default.
- W2891314300 hasAuthorship W2891314300A5033417581 @default.
- W2891314300 hasAuthorship W2891314300A5042611719 @default.
- W2891314300 hasAuthorship W2891314300A5053214575 @default.
- W2891314300 hasAuthorship W2891314300A5065505722 @default.
- W2891314300 hasAuthorship W2891314300A5065887066 @default.
- W2891314300 hasAuthorship W2891314300A5081454914 @default.
- W2891314300 hasBestOaLocation W28913143001 @default.
- W2891314300 hasConcept C126322002 @default.
- W2891314300 hasConcept C159047783 @default.
- W2891314300 hasConcept C159654299 @default.
- W2891314300 hasConcept C203014093 @default.
- W2891314300 hasConcept C2776553844 @default.
- W2891314300 hasConcept C2777451964 @default.
- W2891314300 hasConcept C2777910003 @default.
- W2891314300 hasConcept C2778494684 @default.
- W2891314300 hasConcept C2779110727 @default.
- W2891314300 hasConcept C2779775996 @default.
- W2891314300 hasConcept C2780898057 @default.
- W2891314300 hasConcept C2908647359 @default.
- W2891314300 hasConcept C45189115 @default.
- W2891314300 hasConcept C523546767 @default.
- W2891314300 hasConcept C54355233 @default.
- W2891314300 hasConcept C71924100 @default.
- W2891314300 hasConcept C86803240 @default.
- W2891314300 hasConcept C89423630 @default.
- W2891314300 hasConcept C99454951 @default.
- W2891314300 hasConceptScore W2891314300C126322002 @default.
- W2891314300 hasConceptScore W2891314300C159047783 @default.
- W2891314300 hasConceptScore W2891314300C159654299 @default.
- W2891314300 hasConceptScore W2891314300C203014093 @default.
- W2891314300 hasConceptScore W2891314300C2776553844 @default.
- W2891314300 hasConceptScore W2891314300C2777451964 @default.
- W2891314300 hasConceptScore W2891314300C2777910003 @default.
- W2891314300 hasConceptScore W2891314300C2778494684 @default.
- W2891314300 hasConceptScore W2891314300C2779110727 @default.
- W2891314300 hasConceptScore W2891314300C2779775996 @default.
- W2891314300 hasConceptScore W2891314300C2780898057 @default.
- W2891314300 hasConceptScore W2891314300C2908647359 @default.