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- W2891372283 abstract "Abstract Using molecular analysis, we can evaluate coagulopathy like never before. Nevertheless, the Core Laboratory (in house or commercial) provides most tools to making many of these diagnoses, and it is only under certain circumstances, for example, with equivocal values or when we require additional information that may be important for the patient, the patient's family, or family planning, which we should proceed with molecular testing. This chapter will provide an overview of molecular testing for both inherited thrombophilia and bleeding entities. Although molecular testing is available in all the below described entities, it is only in the setting of a prothrombin G20210A mutation where molecular testing is the primary method of diagnosis. Even some of the most common coagulopathic entities, factor V Leiden and von Willebrand disease, can be evaluated in the Core Laboratory via activated protein C resistance and von Willebrand factor activity and antigen levels, respectively." @default.
- W2891372283 created "2018-09-27" @default.
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- W2891372283 date "2019-01-01" @default.
- W2891372283 modified "2023-10-16" @default.
- W2891372283 title "Molecular Testing in Coagulation" @default.
- W2891372283 doi "https://doi.org/10.1016/b978-0-12-813726-0.00161-6" @default.
- W2891372283 hasPublicationYear "2019" @default.
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