Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891387283> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2891387283 endingPage "1760" @default.
- W2891387283 startingPage "1755" @default.
- W2891387283 abstract "Abstract In this work, a novel initial testing assay based on liquid chromatography–mass spectrometry is presented, enabling the detection of peptidic drugs and drug candidates (< 2 kDa) prohibited in sports. The assay covers representatives and metabolites of gonadotropin releasing hormone and its analogs (GnRHs), growth hormone secretagogues (GHS), growth hormone releasing peptides (GHRPs), and the Vasopressin‐analog Desmopressin. The general objective of this work was to reduce sample preparation efforts to a minimum while preserving highest possible sensitivity and specificity of the assay, demonstrating limits of detection between 50 and 200 pg/mL. Here, a “dilute‐and‐inject” strategy provides the simplest conceivable sample preparation procedure. Furthermore, the combination of well‐established strategies for the determination of peptides, such as two‐dimensional liquid chromatography, dimethyl sulfoxide (DMSO)‐assisted electrospray ionization, high resolution mass spectrometric detection and a tailored reporter template, which facilitates data review enormously, provides a high‐throughput initial testing assay for lower molecular mass peptidic and peptide‐related analytes." @default.
- W2891387283 created "2018-09-27" @default.
- W2891387283 creator A5003407357 @default.
- W2891387283 creator A5017490382 @default.
- W2891387283 creator A5026437283 @default.
- W2891387283 creator A5047214155 @default.
- W2891387283 date "2018-11-01" @default.
- W2891387283 modified "2023-09-28" @default.
- W2891387283 title "Recent improvements in sports drug testing concerning the initial testing for peptidic drugs (< 2 kDa) - sample preparation, mass spectrometric detection, and data review" @default.
- W2891387283 cites W2132871018 @default.
- W2891387283 cites W2135970879 @default.
- W2891387283 cites W2147773057 @default.
- W2891387283 cites W2172505200 @default.
- W2891387283 cites W2520413716 @default.
- W2891387283 cites W2606787706 @default.
- W2891387283 cites W2765495891 @default.
- W2891387283 cites W2793277722 @default.
- W2891387283 cites W405674942 @default.
- W2891387283 doi "https://doi.org/10.1002/dta.2503" @default.
- W2891387283 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30239151" @default.
- W2891387283 hasPublicationYear "2018" @default.
- W2891387283 type Work @default.
- W2891387283 sameAs 2891387283 @default.
- W2891387283 citedByCount "20" @default.
- W2891387283 countsByYear W28913872832018 @default.
- W2891387283 countsByYear W28913872832019 @default.
- W2891387283 countsByYear W28913872832020 @default.
- W2891387283 countsByYear W28913872832021 @default.
- W2891387283 countsByYear W28913872832022 @default.
- W2891387283 countsByYear W28913872832023 @default.
- W2891387283 crossrefType "journal-article" @default.
- W2891387283 hasAuthorship W2891387283A5003407357 @default.
- W2891387283 hasAuthorship W2891387283A5017490382 @default.
- W2891387283 hasAuthorship W2891387283A5026437283 @default.
- W2891387283 hasAuthorship W2891387283A5047214155 @default.
- W2891387283 hasConcept C10390740 @default.
- W2891387283 hasConcept C162356407 @default.
- W2891387283 hasConcept C185592680 @default.
- W2891387283 hasConcept C2778576202 @default.
- W2891387283 hasConcept C2779281246 @default.
- W2891387283 hasConcept C40684141 @default.
- W2891387283 hasConcept C43617362 @default.
- W2891387283 hasConcept C55493867 @default.
- W2891387283 hasConceptScore W2891387283C10390740 @default.
- W2891387283 hasConceptScore W2891387283C162356407 @default.
- W2891387283 hasConceptScore W2891387283C185592680 @default.
- W2891387283 hasConceptScore W2891387283C2778576202 @default.
- W2891387283 hasConceptScore W2891387283C2779281246 @default.
- W2891387283 hasConceptScore W2891387283C40684141 @default.
- W2891387283 hasConceptScore W2891387283C43617362 @default.
- W2891387283 hasConceptScore W2891387283C55493867 @default.
- W2891387283 hasIssue "11-12" @default.
- W2891387283 hasLocation W28913872831 @default.
- W2891387283 hasLocation W28913872832 @default.
- W2891387283 hasOpenAccess W2891387283 @default.
- W2891387283 hasPrimaryLocation W28913872831 @default.
- W2891387283 hasRelatedWork W1971951278 @default.
- W2891387283 hasRelatedWork W2005997170 @default.
- W2891387283 hasRelatedWork W2040912236 @default.
- W2891387283 hasRelatedWork W2066558430 @default.
- W2891387283 hasRelatedWork W2074280965 @default.
- W2891387283 hasRelatedWork W2165368246 @default.
- W2891387283 hasRelatedWork W2320312871 @default.
- W2891387283 hasRelatedWork W2371154968 @default.
- W2891387283 hasRelatedWork W2399218251 @default.
- W2891387283 hasRelatedWork W2439381630 @default.
- W2891387283 hasVolume "10" @default.
- W2891387283 isParatext "false" @default.
- W2891387283 isRetracted "false" @default.
- W2891387283 magId "2891387283" @default.
- W2891387283 workType "article" @default.