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- W2891392105 abstract "Four ring-A seco-cucurbitane triterpenoids, colocynthenins A-D (1-4), together with seven known cucurbitane triterpenoids (5-11), were isolated from the fruits of Citrullus colocynthis. Their structures and absolute configurations were elucidated based on spectroscopic analysis and quantum chemical ECD calculations. Compound 1 possesses an unprecedented 2,11-lactone moiety, while compound 2 is the first reported cucurbitane triterpenoid with an unusual cyano group. Compounds 1 and 3 showed acetylcholinesterase inhibitory activities in a standard in vitro assay, with IC50 values of 2.6 and 3.1 μM, respectively." @default.
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- W2891392105 date "2018-09-05" @default.
- W2891392105 modified "2023-10-12" @default.
- W2891392105 title "Colocynthenins A–D, Ring-A <i>seco</i>-Cucurbitane Triterpenoids from the Fruits of <i>Citrullus colocynthis</i>" @default.
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- W2891392105 doi "https://doi.org/10.1021/acs.jnatprod.8b00461" @default.
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