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- W2891394773 abstract "Susceptibility testing of fungi against antifungal drugs commonly used for therapy is a key component of the care of patients with invasive fungal infections. Antifungal susceptibility testing (AFST) has progressed in recent decades to finally become standardized and available as both Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility Testing (EUCAST) reference methods and in commercial manual/automated phenotypic methods. In clinical practice, the Sensititre YeastOne and Etest methods are widely used for AFST, particularly for sterile site isolates of Candida. Nevertheless, AFST is moving toward new phenotypic methods, such as matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS), that are capable of providing rapid, and potentially more actionable, results for the treating clinician. Our objective is to summarize updated data on phenotypic methods for AFST of Candida and Aspergillus species and to assess their significance in view of opposing, but emerging, molecular genotypic methods." @default.
- W2891394773 created "2018-09-27" @default.
- W2891394773 creator A5084427308 @default.
- W2891394773 date "2018-09-15" @default.
- W2891394773 modified "2023-09-30" @default.
- W2891394773 title "Susceptibility Testing of Fungi to Antifungal Drugs" @default.
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- W2891394773 doi "https://doi.org/10.3390/jof4030110" @default.
- W2891394773 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6162686" @default.
- W2891394773 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30223554" @default.
- W2891394773 hasPublicationYear "2018" @default.
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