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- W2891413277 abstract "The study sought to assess the prognostic impact of type 2 diabetes in patients presenting with ventricular tachyarrhythmias on admission.Data regarding the prognostic outcome of diabetics presenting with ventricular tachyarrhythmias is limited.A large retrospective registry was used including all consecutive patients presenting with ventricular tachycardia (VT) and fibrillation (VF) on admission from 2002 to 2016. Patients with type 2 diabetes (diabetics) were compared to non-diabetics applying multivariable Cox regression models and propensity-score matching for evaluation of the primary prognostic endpoint of long-term all-cause mortality at 2 years. Secondary prognostic endpoints were cardiac death at 24 h, in-hospital death at index, all-cause mortality at 30 days, all-cause mortality in patients surviving index hospitalization at 2 years (i.e. after discharge) and rehospitalization due to recurrent ventricular tachyarrhythmias at 2 years.In 2411 unmatched high-risk patients with ventricular tachyarrhythmias, diabetes was present in 25% compared to non-diabetics (75%). Rates of VT (57% vs. 56%) and VF (43% vs. 44%) were comparable in both groups. Multivariable Cox regression models revealed diabetics associated with the primary endpoint of long-term all-cause mortality at 2 years (HR = 1.513; p = 0.001), which was still proven after propensity score matching (46% vs. 33%, log rank p = 0.001; HR = 1.525; p = 0.001). The rates of secondary endpoints were higher for in-hospital death at index, all-cause mortality at 30 days, as well as after discharge, but not for cardiac death at 24 h or rehospitalization due to recurrent ventricular tachyarrhythmias.Presence of type 2 diabetes is independently associated with an increase of all-cause mortality in patients presenting with ventricular tachyarrhythmias on admission." @default.
- W2891413277 created "2018-09-27" @default.
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- W2891413277 date "2018-09-10" @default.
- W2891413277 modified "2023-10-17" @default.
- W2891413277 title "Type 2 diabetes is independently associated with all-cause mortality secondary to ventricular tachyarrhythmias" @default.
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- W2891413277 doi "https://doi.org/10.1186/s12933-018-0768-y" @default.
- W2891413277 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6130079" @default.
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