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- W2891421425 abstract "Intra-periodontal pocket drug delivery systems, such as liquid crystalline systems, are widely utilized improving the drug release control and the therapy. Propolis is used in the treatment of periodontal diseases, reducing the inflammatory and infectious conditions. Iron oxide magnetic nanoparticles (MNPs) can improve the treatment when an alternating external magnetic field (AEMF) is applied, increasing the local temperature. The aim of this study was to develop a liquid crystalline system containing MNPs for intra-periodontal pocket propolis release. MNPs were prepared using iron salts and the morphological, size, thermal, x-ray diffraction, magnetometry, and Mössbauer spectroscopy analyses were performed. Cytotoxicity studies using Artemia salina and fibroblasts were also accomplished. The systems were prepared using polyoxyethylene (10) oleyl ether, isopropyl myristate, purified water, and characterized by polarized optical microscopy, rheometry, and in vitro drug release profile using a periodontal pocket simulator apparatus. The antifungal activity of the systems was investigated against Candida spp. using an AEMF. MNPs displayed nanometric size, were monodisperse, and they displayed very low cytotoxicity. Microscopically homogeneous formulations were obtained displaying important physicochemical and biological properties. The system displayed prolonged release of propolis and important in vitro fungicide activity, which was increased when the AEMF was applied, indicating a potentially alternative therapy for the treatment of the periodontal disease." @default.
- W2891421425 created "2018-09-27" @default.
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- W2891421425 date "2018-09-12" @default.
- W2891421425 modified "2023-10-04" @default.
- W2891421425 title "Thermal Magnetic Field Activated Propolis Release From Liquid Crystalline System Based on Magnetic Nanoparticles" @default.
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- W2891421425 cites W1705080725 @default.
- W2891421425 cites W1783213284 @default.
- W2891421425 cites W1798031430 @default.
- W2891421425 cites W1964633767 @default.
- W2891421425 cites W1971474475 @default.
- W2891421425 cites W1973933728 @default.
- W2891421425 cites W1974174795 @default.
- W2891421425 cites W1977072597 @default.
- W2891421425 cites W1978980358 @default.
- W2891421425 cites W1980434776 @default.
- W2891421425 cites W1980595924 @default.
- W2891421425 cites W1981039947 @default.
- W2891421425 cites W1988359000 @default.
- W2891421425 cites W1990823750 @default.
- W2891421425 cites W1994080141 @default.
- W2891421425 cites W1995465307 @default.
- W2891421425 cites W1997051735 @default.
- W2891421425 cites W1997761785 @default.
- W2891421425 cites W2000930067 @default.
- W2891421425 cites W2002516695 @default.
- W2891421425 cites W2004055720 @default.
- W2891421425 cites W2014190354 @default.
- W2891421425 cites W2021632712 @default.
- W2891421425 cites W2032664626 @default.
- W2891421425 cites W2035640123 @default.
- W2891421425 cites W2038194129 @default.
- W2891421425 cites W2039489160 @default.
- W2891421425 cites W2039724979 @default.
- W2891421425 cites W2043598314 @default.
- W2891421425 cites W2046058810 @default.
- W2891421425 cites W2051183893 @default.
- W2891421425 cites W2060194702 @default.
- W2891421425 cites W2064558058 @default.
- W2891421425 cites W2074000195 @default.
- W2891421425 cites W2081840436 @default.
- W2891421425 cites W2083005545 @default.
- W2891421425 cites W2092757890 @default.
- W2891421425 cites W2094605768 @default.
- W2891421425 cites W2095005430 @default.
- W2891421425 cites W2104814850 @default.
- W2891421425 cites W2114696795 @default.
- W2891421425 cites W2115439624 @default.
- W2891421425 cites W2117326659 @default.
- W2891421425 cites W2117457888 @default.
- W2891421425 cites W2125313424 @default.
- W2891421425 cites W2125399207 @default.
- W2891421425 cites W2126346850 @default.
- W2891421425 cites W2130977758 @default.
- W2891421425 cites W2137137814 @default.
- W2891421425 cites W2137267593 @default.
- W2891421425 cites W2141376351 @default.
- W2891421425 cites W2141479958 @default.
- W2891421425 cites W2141824074 @default.
- W2891421425 cites W2143745126 @default.
- W2891421425 cites W2146482929 @default.
- W2891421425 cites W2149819749 @default.
- W2891421425 cites W2151260845 @default.
- W2891421425 cites W2153197371 @default.
- W2891421425 cites W2158118026 @default.
- W2891421425 cites W2159097326 @default.
- W2891421425 cites W2159326694 @default.
- W2891421425 cites W2232227669 @default.
- W2891421425 cites W2235017840 @default.
- W2891421425 cites W2370764125 @default.
- W2891421425 cites W2406484772 @default.
- W2891421425 cites W2464700236 @default.
- W2891421425 cites W2519095460 @default.
- W2891421425 cites W2566603197 @default.
- W2891421425 cites W2602858717 @default.
- W2891421425 cites W2604364368 @default.
- W2891421425 cites W2621225149 @default.
- W2891421425 cites W2736269864 @default.
- W2891421425 cites W2767122866 @default.
- W2891421425 cites W2769709841 @default.
- W2891421425 cites W3007599434 @default.
- W2891421425 cites W4211210212 @default.
- W2891421425 cites W54782832 @default.
- W2891421425 doi "https://doi.org/10.1208/s12249-018-1163-4" @default.
- W2891421425 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30209790" @default.
- W2891421425 hasPublicationYear "2018" @default.