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- W2891446394 abstract "Diabetes mellitus (DM) with its micro- and macrocomplications is the leading global epidemic of the 21st century. The aim of the research is to determine possible changes in the complete blood count (CBC) parameters depending on glycemic controlin patients with Type 2 diabetes mellitus (T2DM).The study included a total of 178 patients with T2DM, both gender over the age of 40 years, from the Health Care Center »Dr Milorad Mika Pavlović« Indjija, Serbia. To notice the possible correlation between the CBC parameters and glucose control in T2DM, the subjects were divided in two groups with HbA1c ≤ 7% and with HbA1c>7%. We analysed CBC parameters, parameters of glycoregulation, lipid status using standard biochemical methods, performed anthropometric measurements and collected patients data by questionnaire and electronic patient card.There was statistical difference between HbA1c groups for PMDW (p=0.045), HDL (p=0.0067). Using univariate linear regression it is shown that PCT was correlated with WBC (p=0.0005), neutrophils (p=0.046), monocytes (p=0.003); MPM was associated with MPV (p=0.0005); MPC (p=0.0005), PDW (P=0.0005), GLU0 (p=0.034), HDL-C (p=0.005); PMDW was correlated with HbA1c% (p=0.049), GLU0 (p=0.013), HDL-C (p=0.001), BW (p=0.043) in all patients.Based on our study results it may be concluded that some of the parameters of CBC could be useful tool in following glycemic control of diabetics.Diabetes mellitus (DM) sa mikro i makrokomplikacijama je vodeća globalna epidemija 21. veka. Cilj istraživanja je da se utvrde eventualne promene parametara kompletne krvne slike (KKS) u zavisnosti od glikoregulacije kod pacijenata sa šećernom bolesti tip 2 (DM tip 2).Istraživanjem je obuhvaćeno ukupno 178 pacijenata sa DM tip 2, oba pola, starijih od 40 godina, iz Doma zdravlja »Dr Milorad Mika Pavlović«; Inđija, Srbija. Da bi se utvrdila moguća povezanost između parametara KKS i glikoregulacije u T2DM, ispitanici su podeljeni u dve grupe, sa HbA1c ≤ 7% i sa vrednostima HbA1c>7%. Analizirani su parametri KKS, parametri glikoregulacije, lipidni status korišćenjem standardnih biohemijskih postupaka, a vršena su i antropometrijska merenja. Podaci od pacijenata prikupljeni su putem upitnika i elektronskog kartona pacijenta.Utvrđena je statistički značajna razlika između grupa za PMDW (p=0,045), HDL-C (p=0,0067). Kod svih pacijenata (univarijabilna linearna regresija) rezultati su pokazali daje PCT povezan sa leukocitima (p=0,0005), neutrofilima (p=0,046), monocitima (p=0,003); MPM je u korelaciji sa MPV (p=0,0005); MPC (p=0,0005), PDW (p=0,0005), GLU0 (p=0,034), HDL-C (p=0,005); PMDW je u korelaciji sa HbA1c% (p=0,049), GLU0 (p=0,013), HDL-C (p=0,001), telesnom masom (p=0,043).Na osnovu dobijenih rezultata našeg istraživanja može se zaključiti da postoji povezanost između pojedinih hematoloških parametara i glikoregulacije kod pacijenata sa dijabetesom." @default.
- W2891446394 created "2018-09-27" @default.
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- W2891446394 date "2019-03-03" @default.
- W2891446394 modified "2023-10-14" @default.
- W2891446394 title "Relationship between hematological parameters and glycemic control in type 2 diabetes mellitus patients" @default.
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- W2891446394 doi "https://doi.org/10.2478/jomb-2018-0021" @default.
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