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- W2891451275 abstract "Abstract Good sleep plays a central role in healthy brain functioning and in overall health. The vitality of sleep is just as important to animals as it is to humans. The fact that animals from frogs to great apes sleep provides evidence that sleep serves a basic physiological need in all living beings. Sleep can be assessed by detecting electrical brain waves using electroencephalography (EEG) or polysomnography. On EEG, it can be appreciated that sleep is broken into two broad categories: rapid eye movement (REM) sleep and non-REM sleep (NREM). NREM is further divided into light sleep and slow-wave sleep. When any of these is disrupted, in the short term, there can be consequences such as poor memory, difficulty concentrating, and daytime sleepiness. Chronic disruption of sleep can lead to obesity, hypertension, and diabetes. Translatability to human sleep of studying sleep in rats, dogs, or monkeys is discussed. Given the importance of sleep, evaluation of compounds' effects on sleep should be a part of drug discovery and development." @default.
- W2891451275 created "2018-09-27" @default.
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- W2891451275 date "2019-01-01" @default.
- W2891451275 modified "2023-10-16" @default.
- W2891451275 title "Sleep and Sleep Disruption" @default.
- W2891451275 doi "https://doi.org/10.1016/b978-0-12-812206-8.00006-6" @default.
- W2891451275 hasPublicationYear "2019" @default.
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