FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891461406> ?p ?o ?g. }

• W2891461406 abstract "We found that Vibrio furnissii can utilize aerobactin (AERO) as a xenosiderophore. A homology search of its genome revealed that this bacterium possesses genes encoding an AERO-mediated iron acquisition system similar to that of V. vulnificus. The system consists of the ABC transporter gene vatCDB, the GntR-type transcriptional repressor gene iutR, and the outer membrane receptor gene iutA. The functions of the vatCDB operon and iutA in V. furnissii were confirmed by the inability of the corresponding deletion mutants to utilize AERO. Reverse transcription-quantitative PCR revealed that iutA transcription under iron-limiting conditions was extensively activated by the addition of AERO to the growth medium; therefore, we focused on elucidating this phenomenon. Electrophoretic mobility shift and DNase I footprinting assays revealed that glutathione S-transferase-fused IutR (GST-IutR) bound directly to a specific palindromic sequence in the iutA promoter region. However, GST-IutR did not bind to this sequence when either AERO or ferric AERO was present in the assay mixture. These in vitro findings suggest that, under iron-limiting conditions, iutA transcription in V. furnissii is artfully regulated both by IutR, acting as a direct repressor of iutA, and by AERO, acting as an effector for IutR, leading to the derepression of iutA transcription." @default.
• W2891461406 created "2018-09-27" @default.
• W2891461406 creator A5004365170 @default.
• W2891461406 creator A5036213536 @default.
• W2891461406 creator A5053401826 @default.
• W2891461406 creator A5056589260 @default.
• W2891461406 creator A5064222520 @default.
• W2891461406 creator A5077215453 @default.
• W2891461406 date "2018-09-07" @default.
• W2891461406 modified "2023-09-26" @default.
• W2891461406 title "Transcriptional regulation of the ferric aerobactin receptor gene by a GntR-like repressor IutR in Vibrio furnissii" @default.
• W2891461406 cites W1578338446 @default.
• W2891461406 cites W1931700765 @default.
• W2891461406 cites W1933066607 @default.
• W2891461406 cites W1971226186 @default.
• W2891461406 cites W1972010400 @default.
• W2891461406 cites W1974127479 @default.
• W2891461406 cites W1977680030 @default.
• W2891461406 cites W1982657846 @default.
• W2891461406 cites W1986555537 @default.
• W2891461406 cites W1986962297 @default.
• W2891461406 cites W2006768126 @default.
• W2891461406 cites W2014723793 @default.
• W2891461406 cites W2040249246 @default.
• W2891461406 cites W2069798165 @default.
• W2891461406 cites W2088167775 @default.
• W2891461406 cites W2099143902 @default.
• W2891461406 cites W2104588351 @default.
• W2891461406 cites W2124174825 @default.
• W2891461406 cites W2131282911 @default.
• W2891461406 cites W2133773386 @default.
• W2891461406 cites W2139303349 @default.
• W2891461406 cites W2143226173 @default.
• W2891461406 cites W2149656458 @default.
• W2891461406 cites W2152895717 @default.
• W2891461406 cites W2153117962 @default.
• W2891461406 cites W2157667237 @default.
• W2891461406 cites W2158353541 @default.
• W2891461406 cites W2161425107 @default.
• W2891461406 cites W2557496587 @default.
• W2891461406 cites W2584901038 @default.
• W2891461406 cites W36629840 @default.
• W2891461406 cites W4210964542 @default.
• W2891461406 doi "https://doi.org/10.1093/femsle/fny220" @default.
• W2891461406 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30203068" @default.
• W2891461406 hasPublicationYear "2018" @default.
• W2891461406 type Work @default.
• W2891461406 sameAs 2891461406 @default.
• W2891461406 citedByCount "1" @default.
• W2891461406 countsByYear W28914614062021 @default.
• W2891461406 crossrefType "journal-article" @default.
• W2891461406 hasAuthorship W2891461406A5004365170 @default.
• W2891461406 hasAuthorship W2891461406A5036213536 @default.
• W2891461406 hasAuthorship W2891461406A5053401826 @default.
• W2891461406 hasAuthorship W2891461406A5056589260 @default.
• W2891461406 hasAuthorship W2891461406A5064222520 @default.
• W2891461406 hasAuthorship W2891461406A5077215453 @default.
• W2891461406 hasBestOaLocation W28914614061 @default.
• W2891461406 hasConcept C104317684 @default.
• W2891461406 hasConcept C138885662 @default.
• W2891461406 hasConcept C143065580 @default.
• W2891461406 hasConcept C150194340 @default.
• W2891461406 hasConcept C153911025 @default.
• W2891461406 hasConcept C158448853 @default.
• W2891461406 hasConcept C179926584 @default.
• W2891461406 hasConcept C186310378 @default.
• W2891461406 hasConcept C203075996 @default.
• W2891461406 hasConcept C2778487981 @default.
• W2891461406 hasConcept C2778910516 @default.
• W2891461406 hasConcept C41895202 @default.
• W2891461406 hasConcept C54355233 @default.
• W2891461406 hasConcept C547475151 @default.
• W2891461406 hasConcept C73766848 @default.
• W2891461406 hasConcept C86339819 @default.
• W2891461406 hasConcept C86803240 @default.
• W2891461406 hasConcept C95444343 @default.
• W2891461406 hasConceptScore W2891461406C104317684 @default.
• W2891461406 hasConceptScore W2891461406C138885662 @default.
• W2891461406 hasConceptScore W2891461406C143065580 @default.
• W2891461406 hasConceptScore W2891461406C150194340 @default.
• W2891461406 hasConceptScore W2891461406C153911025 @default.
• W2891461406 hasConceptScore W2891461406C158448853 @default.
• W2891461406 hasConceptScore W2891461406C179926584 @default.
• W2891461406 hasConceptScore W2891461406C186310378 @default.
• W2891461406 hasConceptScore W2891461406C203075996 @default.
• W2891461406 hasConceptScore W2891461406C2778487981 @default.
• W2891461406 hasConceptScore W2891461406C2778910516 @default.
• W2891461406 hasConceptScore W2891461406C41895202 @default.
• W2891461406 hasConceptScore W2891461406C54355233 @default.
• W2891461406 hasConceptScore W2891461406C547475151 @default.
• W2891461406 hasConceptScore W2891461406C73766848 @default.
• W2891461406 hasConceptScore W2891461406C86339819 @default.
• W2891461406 hasConceptScore W2891461406C86803240 @default.
• W2891461406 hasConceptScore W2891461406C95444343 @default.
• W2891461406 hasIssue "20" @default.
• W2891461406 hasLocation W28914614061 @default.
• W2891461406 hasLocation W28914614062 @default.
• W2891461406 hasOpenAccess W2891461406 @default.
• W2891461406 hasPrimaryLocation W28914614061 @default.
• W2891461406 hasRelatedWork W106238709 @default.

• next